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Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59695. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
CKAP1 binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cytoskeleton associated protein 1; Cytoskeleton-associated protein 1; Cytoskeleton-associated protein CKAPI; Tubulin-folding cofactor B; Tubulin-specific chaperone B
基因别名: CG22; CKAP1; CKAPI; TBCB
UniProt ID: (Human) Q99426
Entrez Gene ID: (Human) 1155