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Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65840. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Associates with the NF-kappa-B complex and suppresses its transcriptional activity (PubMed:15799966).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: COMM domain-containing protein 7; RP11-503P21.3
基因别名: C20orf92; COMMD7; dJ1085F17.3
UniProt ID: (Human) Q86VX2
Entrez Gene ID: (Human) 149951