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Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59592. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
CRLF1 encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: class I cytokine receptor; CLF-1; Cytokine receptor-like factor 1; cytokine type 1 receptor CRLP-1; Cytokine-like factor 1; ZcytoR5
基因别名: CISS; CISS1; CLF; CLF-1; CRLF1; NR6; UNQ288/PRO327; zcytor5
UniProt ID: (Human) O75462
Entrez Gene ID: (Human) 9244