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Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52400. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. The encoded protein modulates the activation of ARF genes by CYTH1. This protein interacts with CYTH1 and SNX27 proteins and may act to sequester CYTH1 protein in the cytoplasm.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CASP; Cbp HE; CYBR; Cytohesin binder and regulator; cytohesin binding protein HE; cytohesin-1 interacting protein; Cytohesin-associated scaffolding protein; Cytohesin-binding protein HE; Cytohesin-interacting protein; Pleckstrin homology Sec7 and coiled-coil domains-binding protein; pleckstrin homology, Sec7 and coiled-coil domains, binding protein; pleckstrin homology, Sec7 and coiled/coil domains, binding protein; Sec7
基因别名: B3-1; CASP; CYBR; CYTHIP; CYTIP; HE; PSCDBP
UniProt ID: (Human) O60759
Entrez Gene ID: (Human) 9595