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Highest antigen sequence indentity to the following orthologs: Mouse (51%), Rat (51%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56337. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CUL-7; Cullin-7
基因别名: 3M1; CUL7; dJ20C7.5; KIAA0076
UniProt ID: (Human) Q14999
Entrez Gene ID: (Human) 9820