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Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-64219. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: c-myc promoter binding protein; C-myc promoter-binding protein; DENN domain-containing protein 4A; DENN/MADD domain containing 4A
基因别名: DENND4A; IRLB; MYCPBP
UniProt ID: (Human) Q7Z401
Entrez Gene ID: (Human) 10260