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Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66004. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is required for the assembly of axonemal inner and outer dynein arms and plays a role in assembling dynein complexes for transport into cilia. Defects in this gene are a cause of primary ciliary dyskinesia type 2 (CILD2). Several transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: dynein; dynein (axonemal) assembly factor 3; Dynein axonemal assembly factor 3; dynein, axonemal, assembly factor 3; UPF0470 protein C19orf51
基因别名: C19orf51; CILD2; DAB1; DNAAF3; PCD; PF22
UniProt ID: (Human) Q8N9W5
Entrez Gene ID: (Human) 352909