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Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57958. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Axonemal beta dynein heavy chain 5; Ciliary dynein heavy chain 5; Dynein axonemal heavy chain 5; dynein, axonemal, heavy chain 5; dynein, axonemal, heavy polypeptide 5
基因别名: CILD3; DNAH5; DNAHC5; HL1; KIAA1603; KTGNR; PCD
UniProt ID: (Human) Q8TE73
Entrez Gene ID: (Human) 1767