Search Thermo Fisher Scientific
Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140270. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cadherin family member 4; Desmoglein-1; Desmosomal glycoprotein 1; DG1; Pemphigus foliaceus antigen
基因别名: CDHF4; DG1; DSG; DSG1; EPKHE; EPKHIA; PPKS1; SPPK1
UniProt ID: (Human) Q02413
Entrez Gene ID: (Human) 1828