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产品信息
100-27-25UG
应用
建议稀释比
已发表文章
产品规格
种属
Human
已发表种属
Human,
Mouse,
Rat
Expression System
E. coli
氨基酸序列
MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT
分子量
22.7 kDa
分类
Recombinant
类型
Protein
纯度
≥ 95% by SDS-PAGE gel and HPLC analyses.
内毒素浓度
<1 EU/µg
活性
Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 10^5 units/mg.
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
-20°C
运输条件
Ambient
产品详细信息
100-27-1MG will be provided as 4 x 250 µg (100-27-250UG).
100-27-500UG will be provided as 2 x 250 µg (100-27-250UG).
Recombinant Human FGF-17 is a 22.7 kDa protein consisting of 195 amino acid residues.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
靶标信息
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was shown to be prominently expressed in the cerebellum and cortex. The mouse homolog of this gene was localized to specific sites in the midline structures of the forebrain, the midbrain-hindbrain junction, developing skeleton and developing arteries, which suggests a role in central nervous system, bone and vascular development. This gene was referred to as FGF-13 in reference 2, however, its amino acid sequence and chromosomal localization are identical to FGF17.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FGF; FGF-17; Fibroblast growth factor; Fibroblast growth factor 17
基因别名: FGF-13; FGF-17; FGF17; HH20; UNQ161/PRO187
UniProt ID: (Human) O60258
Entrez Gene ID: (Human) 8822
