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Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60287. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon-gamma-G-gamma-A-delta-beta-3'.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: beta globin chain; Beta-globin; hemoglobin beta; Hemoglobin beta chain; Hemoglobin subunit beta; hemoglobin, beta
基因别名: beta-globin; CD113t-C; HBB
UniProt ID: (Human) P68871
Entrez Gene ID: (Human) 3043