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Highest antigen sequence indentity to the following orthologs: Mouse (48%), Rat (48%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-64102. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ITLN1 has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. ITLN1 increases AKT phosphorylation in the absence and presence of insulin. ITLN1 may play a role in the defense system against microorganisms. ITLN1 may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. ITLN1 may be involved in iron metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Endothelial lectin HL-1; FLJ20022; Galactofuranose-binding lectin; intelectin 1 (galactofuranose binding); Intelectin-1; Intestinal lactoferrin receptor; ITLN-1; Omentin
基因别名: hIntL; HL-1; HL1; INTL; ITLN; ITLN1; LFR; omentin; UNQ640/PRO1270
UniProt ID: (Human) Q8WWA0
Entrez Gene ID: (Human) 55600