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Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82765. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD339; jagged canonical Notch ligand 1; Jagged1; Protein jagged-1
基因别名: AGS; AHD; AWS; CD339; HJ1; JAG1; JAGL1
UniProt ID: (Human) P78504
Entrez Gene ID: (Human) 182