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Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65833. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: High sulfur keratin-associated protein 11.1; Keratin-associated protein 11-1
基因别名: HACL-1; HACL1; KAP11.1; KRTAP11-1; KRTAP11.1
UniProt ID: (Human) Q8IUC1
Entrez Gene ID: (Human) 337880