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Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60733. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AF4/FMR2 family member 3; AF4/FMR2 family, member 3; lymphoid nuclear protein 4; Lymphoid nuclear protein related to AF4; MLLT2-related protein; Protein LAF-4
基因别名: AFF3; LAF4; MLLT2-like
UniProt ID: (Human) P51826
Entrez Gene ID: (Human) 3899