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产品信息
RP-109770
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
SVTLKLYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSYGLESIQR
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145059. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
LHCGR encodes the receptor for both luteinizing hormone and choriogonadotropin. It is family 1 of G-protein coupled receptors, FSH/LSH/TSH superfamily, and its basic function is acting as luteinizing hormone/choriogonadotropin receptor (gonadotropin receptor). Regulating the development and function of Leyding cells in males. It also plays a role in male secondary sexual characterdevelopment. Mutations in this gonadotropinreceptor results in disorders of male secondary sexual characteristic development, such as familial male precocious puperty and male pseudohermaphtoditism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HCG receptor; hypergonadotropic hypogonadism; LH/CG-R; LHR; Luteinizing hormone receptor; Lutropin receptor; Lutropin-choriogonadotropic hormone receptor; lutropin/choriogonadotropin receptor
基因别名: HHG; LCGR; LGR2; LH/CG-R; LH/CGR; LHCGR; LHR; LHRHR; LSH-R; ULG5
UniProt ID: (Human) P22888
Entrez Gene ID: (Human) 3973
