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Highest antigen sequence indentity to the following orthologs: Mouse (81%), Rat (81%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54281. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The LIM-only (LMO) proteins are nuclear factors characterized by a conserved LIM domain. The LIM domain contains a cysteine-rich zinc-binding motif, present in a variety of transcription factors, including the LIM homeobox (LHX) proteins expressed in the central nervous system. The deduced LMO7 protein is comprised of 1,349 amino acid residues, contains a characteristic zinc finger domain and a 3-prime UTR which possesses a short interspersed nucleotide element (SINE). RT-PCR detects predominant expression of LMO7 in heart, lung, skeletal muscle, and kidney, moderate expression in liver, ovary, brain, pancreas, and testis, and little to no expression in spleen. Research indicates that LMO7 is an afadin- and alpha-actinin-binding protein that connects the nectin-afadin and E-cadherin-catenin systems through alpha-actinin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: F-box only protein 20; F-box protein Fbx20; LIM domain only 7 protein; LIM domain only protein 7; LMO-7; LOMP; LOMP protein; RP11-332E3.2; zinc-finger domain-containing protein
基因别名: FBX20; FBXO20; KIAA0858; LMO7; LOMP
UniProt ID: (Human) Q8WWI1
Entrez Gene ID: (Human) 4008