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Highest antigen sequence indentity to the following orthologs: Mouse (74%), Rat (74%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52665. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BM600 150kD subunit; E170; Epiligrin; Epiligrin 170 kDa subunit; epiligrin alpha 3 subunit; Epiligrin subunit alpha; kalinin 165kD subunit; Kalinin subunit alpha; LAM3, alpha-3 subunit; laminin 5, alpha-3 subunit; laminin A3; Laminin subunit alpha-3; laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin); Laminin-5; laminin-5 alpha 3 chain; Laminin-5 subunit alpha; Laminin-6 subunit alpha; Laminin-7 subunit alpha; nicein 150kD subunit; Nicein subunit alpha
基因别名: BM600; E170; LAMA3; LAMNA; LOCS
UniProt ID: (Human) Q16787
Entrez Gene ID: (Human) 3909