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产品信息
PEP-0898
产品规格
种属反应
Human
分类
Synthetic
类型
Peptide
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
产品详细信息
This peptide corresponds to 14 amino acids near the center of human MAK10.
PEP-0898 can be used as a blocking peptide with polyclonal antibody PA5-20784.
靶标信息
The MAK10 gene encodes a 733-amino acid protein with several regions of similarity to T cell receptor alpha-subunit V (variable) regions in yeast. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult, remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury. The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development. This complex functionally co-assembles in mammalian cells to regulate cell proliferation and is essential for embryonic development, at least in part through the regulation of target of rapamycin (TOR) signaling events. At least two isoforms of MAK10 are known to exist.
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生物信息学
蛋白别名: corneal wound healing-related protein; Embryonic growth-associated protein homolog; MAK10 homolog, amino-acid N-acetyltransferase subunit; N-alpha-acetyltransferase 35, NatC auxiliary subunit; Protein MAK10 homolog; RP11-379P1.1
基因别名: bA379P1.1; EGAP; MAK10; MAK10P; NAA35
UniProt ID: (Human) Q5VZE5
Entrez Gene ID: (Human) 60560
