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Highest antigen sequence indentity to the following orthologs: Mouse (65%), Rat (65%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56557. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: basic, SAP and coiled-coil domain; Megakaryoblastic leukemia 1 protein; Megakaryocytic acute leukemia protein; mixed lineage leukemia; MKL/myocardin-like protein 1; MRTF-A; Myocardin-related transcription factor A
基因别名: BSAC; KIAA1438; MAL; MKL1; MRTF-A; MRTFA
UniProt ID: (Human) Q969V6
Entrez Gene ID: (Human) 57591