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Highest antigen sequence indentity to the following orthologs: Mouse (28%), Rat (28%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84180. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Lymphocyte effector toxicity activation ligand; MGC125309; N2DL-4; NKG2D ligand 4; RAE-1-like transcript 4; RAE1 like transcript 4; Retinoic acid early transcript 1E; UL16 binding protein 4; UL16-binding protein 4; ULBP 4; ULBP4MGC125308
基因别名: bA350J20.7; LETAL; N2DL-4; N2DL4; NKG2DL4; RAET1E; RAET1E2; RL-4; ULBP4; UNQ1867/PRO4303
UniProt ID: (Human) Q8TD07
Entrez Gene ID: (Human) 135250