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Highest antigen sequence indentity to the following orthologs: Mouse (73%), Rat (73%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145118. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
NLRC4 encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CARD, LRR, and NACHT-containing protein; caspase recruitment domain family, member 12; Caspase recruitment domain-containing protein 12; CED-4-like protein Clan; Ice protease-activating factor; ICE-protease activating factor; Ipaf; NLR family CARD domain-containing protein 4; NLR family, CARD domain containing 4; NOD-like receptor C4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4
基因别名: AIFEC; CARD12; CLAN; CLAN1; CLANA; CLANB; CLANC; CLAND; CLR2.1; FCAS4; IPAF; NLRC4; UNQ6189/PRO20215
UniProt ID: (Human) Q9NPP4
Entrez Gene ID: (Human) 58484