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Highest antigen sequence indentity to the following orthologs: Mouse (81%), Rat (81%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59529. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin-Tcf signaling pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dvl-binding protein; hNkd; hNkd1; naked cuticle-1; Naked-1; Protein naked cuticle homolog 1
基因别名: Naked1; NKD; NKD1; PP7246
UniProt ID: (Human) Q969G9
Entrez Gene ID: (Human) 85407