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Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58225. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
PTER is a mammalian homolog to bacterial phosphotriesterases, enzymes that hydrolyze phosphotriester-containing organophosphate pesticides. It is expressed primarily in the proximal renal tubules and the gene has been localized in humans to chromosomal band 10p12 by in situ hybridization. PTER, in addition to FTO, MC4R, and NPC1 has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations. At least two isoforms of PTER are known to exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hPHRP; Parathion hydrolase-related protein; Phosphotriesterase-related protein; resiniferatoxin-binding, phosphotriesterase-related
基因别名: HPHRP; PTER; RPR-1
UniProt ID: (Human) Q96BW5
Entrez Gene ID: (Human) 9317