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PEP-137 is an 18 amino acid synthetic peptide whose sequences are derived from human RanBP2 protein. The sequence of this peptide is (amino to carboxy terminus): M (1)-R-R-S-K-A-D-V-E-R-Y-I-A-S-V-Q-G-S (18)-C
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human RanBP2, catalog # PA1-082. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
RanBP2 interacts with the small GTP-binding protein Ran and forms a large multiprotein complex involved in many biological processes such as mRNA processing, nuclear transport, cell cycle control and postmitotic nuclear reassembly. The protein is identified by western blotting as an apparent molecular mass of 360 kD. It is involved in nucleation of microtubule and control of cell growth by interacting with many protein factors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 358 kDa nucleoporin; acute necrotizing encephalopathy 1 (autosomal dominant); E3 SUMO-protein ligase RanBP2; Nuclear pore complex protein Nup358; nucleoporin 358; Nucleoporin Nup358; P270; Ran-binding protein 2; RanBP2; RBP2; transformation-related protein 2
基因别名: ADANE; ANE1; IIAE3; NUP358; RANBP2; TRP1; TRP2
UniProt ID: (Human) P49792
Entrez Gene ID: (Human) 5903