Search Thermo Fisher Scientific
Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111019. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 domain-containing receptor family, and the low density lipoprotein receptor family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of this locus and Alzheimer's Disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ21930; FLJ39258; LDLR relative with 11 ligand-binding repeats; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; mosaic protein LR11; SorLA; SorLA-1; Sortilin-related receptor; sortilin-related receptor, L(DLR class) A repeats containing; Sorting protein-related receptor containing LDLR class A repeats
基因别名: C11orf32; gp250; LR11; LRP9; SORL1; SORLA; SorLA-1
UniProt ID: (Human) Q92673
Entrez Gene ID: (Human) 6653