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Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 22 kDa actin-binding protein; DKFZp686B01212; DKFZp686P11128; Protein WS3-10; sm22 alpha; SM22-alpha; Smooth muscle protein 22-alpha; Transgelin; transgelin variant 2
基因别名: SM22; SMCC; TAGLN; TAGLN1; WS3-10
UniProt ID: (Human) Q01995
Entrez Gene ID: (Human) 6876