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产品信息
PEP-0856
产品规格
种属反应
Human
分类
Synthetic
类型
Peptide
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Dry ice
产品详细信息
This peptide corresponds to 17 amino acids near the center of human Transthyretin.
PEP-0856 can be used as a blocking peptide with polyclonal antibody PA5-20742.
靶标信息
Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.
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生物信息学
蛋白别名: Amyloidosis I; ATTR; carpal tunnel syndrome 1; epididymis luminal protein 111; pre-albumin; Prealbumin; prealbumin, amyloidosis type I; TBPA; thyroxine-binding prealbumin; Transthyretin
基因别名: CTS; CTS1; HEL111; HsT2651; PALB; TBPA; TTR
UniProt ID: (Human) P02766
Entrez Gene ID: (Human) 7276
