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Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67019. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
WEE1, which is classified as a Ser/Thr kinase by sequence analysis, has been shown to inactivate multiple CDKs by tyrosine phosphorylation. Wee1 protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp686I18166; FLJ16446; WEE1 homolog; WEE1+ homolog; Wee1-like protein kinase; Wee1A kinase; WEE1hu
基因别名: WEE1; WEE1A; WEE1hu
UniProt ID: (Human) P30291
Entrez Gene ID: (Human) 7465