Product References
The dystonia gene THAP1 controls DNA double-strand break repair choice.
Molecular cell
Shinoda K,Zong D,Callen E,Wu W,Dumitrache LC,Belinky F,Chari R,Wong N,Ishikawa M,Stanlie A,Multhaupt-Buell T,Sharma N,Ozelius L,Ehrlich M,McKinnon PJ,Nussenzweig A
315-15 was used in Sample Preparation (FC/FACS) to report that the transcription factors THAP1, YY1, and HCF1 bind directly to the SHLD1 promoter, where they cooperatively maintain the low basal expression of SHLD1, thereby ensuring a proper balance between end protection and resection during double-strand DNA breaks repair.
Thu Jun 17 00:00:00 EDT 2021
TRIM14 Promotes Noncanonical NF-κB Activation by Modulating p100/p52 Stability via Selective Autophagy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Chen M,Zhao Z,Meng Q,Liang P,Su Z,Wu Y,Huang J,Cui J
Wed Jan 01 00:00:00 EST 2020
TRIM14 Promotes Noncanonical NF-κB Activation by Modulating p100/p52 Stability via Selective Autophagy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Chen M,Zhao Z,Meng Q,Liang P,Su Z,Wu Y,Huang J,Cui J
Wed Jan 01 00:00:00 EST 2020
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.
Cell
Gupta R,Somyajit K,Narita T,Maskey E,Stanlie A,Kremer M,Typas D,Lammers M,Mailand N,Nussenzweig A,Lukas J,Choudhary C
Thu May 03 00:00:00 EDT 2018
The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes.
Cell research
Chen J,Cai Z,Bai M,Yu X,Zhang C,Cao C,Hu X,Wang L,Su R,Wang D,Wang L,Yao Y,Ye R,Hou B,Yu Y,Yu S,Li J,Xue Y
Mon Oct 01 00:00:00 EDT 2018
The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes.
Cell research
Chen J,Cai Z,Bai M,Yu X,Zhang C,Cao C,Hu X,Wang L,Su R,Wang D,Wang L,Yao Y,Ye R,Hou B,Yu Y,Yu S,Li J,Xue Y
Mon Oct 01 00:00:00 EDT 2018
Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function.
Proceedings of the National Academy of Sciences of the United States of America
Andreani V,Ramamoorthy S,Pandey A,Lupar E,Nutt SL,Lämmermann T,Grosschedl R
Tue Oct 09 00:00:00 EDT 2018
Generation of an osteoblast-based artificial niche that supports in vitro B lymphopoiesis.
Experimental & molecular medicine
Yu J,Choi S,Kim H,Lee N,Yun H,Kim S,Jeong ST,Rho J
Fri Nov 24 00:00:00 EST 2017
Platelets Mediate Host Defense against Staphylococcus aureus through Direct Bactericidal Activity and by Enhancing Macrophage Activities.
Journal of immunology (Baltimore, Md. : 1950)
Ali RA,Wuescher LM,Dona KR,Worth RG
Sun Jan 01 00:00:00 EST 2017
Rel B-modified dendritic cells possess tolerogenic phenotype and functions on lupus splenic lymphocytes in vitro.
Immunology
Wu H,Lo Y,Chan A,Law KS,Mok MY
Thu Sep 01 00:00:00 EDT 2016
Tolerogenic Phenotype of IFN-γ-Induced IDO+ Dendritic Cells Is Maintained via an Autocrine IDO-Kynurenine/AhR-IDO Loop.
Journal of immunology (Baltimore, Md. : 1950)
Li Q,Harden JL,Anderson CD,Egilmez NK
Mon Aug 01 00:00:00 EDT 2016
Constitutive CD40 Signaling Calibrates Differentiation Outcomes in Responding B Cells via Multiple Molecular Pathways.
Journal of immunology (Baltimore, Md. : 1950)
Basu S,Kaw S,D'Souza L,Vaidya T,Bal V,Rath S,George A
Mon Aug 01 00:00:00 EDT 2016
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity.
Nature
Carmi Y,Spitzer MH,Linde IL,Burt BM,Prestwood TR,Perlman N,Davidson MG,Kenkel JA,Segal E,Pusapati GV,Bhattacharya N,Engleman EG
Thu May 07 00:00:00 EDT 2015
Comparative Biochemical and Functional Analysis of Viral and Human Secreted Tumor Necrosis Factor (TNF) Decoy Receptors.
The Journal of biological chemistry
Pontejo SM,Alejo A,Alcami A
Fri Jun 26 00:00:00 EDT 2015
FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Clatworthy MR,Harford SK,Mathews RJ,Smith KG
Tue Dec 16 00:00:00 EST 2014
Phosphatase Wip1 is essential for the maturation and homeostasis of medullary thymic epithelial cells in mice.
Journal of immunology (Baltimore, Md. : 1950)
Sun L,Li H,Luo H,Zhang L,Hu X,Yang T,Sun C,Chen H,Zhang L,Zhao Y
Sun Sep 15 00:00:00 EDT 2013
MiR-210 is induced by Oct-2, regulates B cells, and inhibits autoantibody production.
Journal of immunology (Baltimore, Md. : 1950)
Mok Y,Schwierzeck V,Thomas DC,Vigorito E,Rayner TF,Jarvis LB,Prosser HM,Bradley A,Withers DR,Mårtensson IL,Corcoran LM,Blenkiron C,Miska EA,Lyons PA,Smith KGC
Sun Sep 15 00:00:00 EDT 2013
The histone methyltransferase MMSET regulates class switch recombination.
Journal of immunology (Baltimore, Md. : 1950)
Pei H,Wu X,Liu T,Yu K,Jelinek DF,Lou Z
Tue Jan 15 00:00:00 EST 2013
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
The Journal of experimental medicine
Yang D,Postnikov YV,Li Y,Tewary P,de la Rosa G,Wei F,Klinman D,Gioannini T,Weiss JP,Furusawa T,Bustin M,Oppenheim JJ
Mon Jan 16 00:00:00 EST 2012
A composite MyD88/CD40 switch synergistically activates mouse and human dendritic cells for enhanced antitumor efficacy.
The Journal of clinical investigation
Narayanan P,Lapteva N,Seethammagari M,Levitt JM,Slawin KM,Spencer DM
Fri Apr 01 00:00:00 EDT 2011
14-3-3sigma regulates B-cell homeostasis through stabilization of FOXO1.
Proceedings of the National Academy of Sciences of the United States of America
Su YW,Hao Z,Hirao A,Yamamoto K,Lin WJ,Young A,Duncan GS,Yoshida H,Wakeham A,Lang PA,Murakami K,Hermeking H,Vogelstein B,Ohashi P,Mak TW
Tue Jan 25 00:00:00 EST 2011
Induction of B-cell lymphoma by UVB radiation in p53 haploinsufficient mice.
BMC cancer
Puebla-Osorio N,Miyahara Y,Coimbatore S,Limón-Flores AY,Kazimi N,Ullrich SE,Zhu C
Wed Jan 26 00:00:00 EST 2011
The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
Immunity
Suzuki K,Maruya M,Kawamoto S,Sitnik K,Kitamura H,Agace WW,Fagarasan S
Fri Jul 23 00:00:00 EDT 2010
Anti-CD40L immune complexes potently activate platelets in vitro and cause thrombosis in FCGR2A transgenic mice.
Journal of immunology (Baltimore, Md. : 1950)
Robles-Carrillo L,Meyer T,Hatfield M,Desai H,Dávila M,Langer F,Amaya M,Garber E,Francis JL,Hsu YM,Amirkhosravi A
Sun Aug 01 00:00:00 EDT 2010
Differential requirement of MALT1 for BAFF-induced outcomes in B cell subsets.
The Journal of experimental medicine
Tusche MW,Ward LA,Vu F,McCarthy D,Quintela-Fandino M,Ruland J,Gommerman JL,Mak TW
Mon Nov 23 00:00:00 EST 2009
Activation, immune polarization, and graft-versus-leukemia activity of donor T cells are regulated by specific subsets of donor bone marrow antigen-presenting cells in allogeneic hemopoietic stem cell transplantation.
Journal of immunology (Baltimore, Md. : 1950)
Li JM,Southerland LT,Lu Y,Darlak KA,Giver CR,McMillin DW,Harris WA,Jaye DL,Waller EK
Tue Dec 15 00:00:00 EST 2009
Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation.
Journal of immunology (Baltimore, Md. : 1950)
Franchi L,Eigenbrod T,Núñez G
Wed Jul 15 00:00:00 EDT 2009
A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2.
Journal of immunology (Baltimore, Md. : 1950)
Izhak L,Wildbaum G,Zohar Y,Anunu R,Klapper L,Elkeles A,Seagal J,Yefenof E,Ayalon-Soffer M,Karin N
Wed Jul 01 00:00:00 EDT 2009
Organ-derived dendritic cells have differential effects on alloreactive T cells.
Blood
Kim TD,Terwey TH,Zakrzewski JL,Suh D,Kochman AA,Chen ME,King CG,Borsotti C,Grubin J,Smith OM,Heller G,Liu C,Murphy GF,Alpdogan O,van den Brink MR
Sat Mar 01 00:00:00 EST 2008
Galectin-1 promotes immunoglobulin production during plasma cell differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Tsai CM,Chiu YK,Hsu TL,Lin IY,Hsieh SL,Lin KI
Wed Oct 01 00:00:00 EDT 2008
Induction of the formyl peptide receptor 2 in microglia by IFN-gamma and synergy with CD40 ligand.
Journal of immunology (Baltimore, Md. : 1950)
Chen K,Iribarren P,Huang J,Zhang L,Gong W,Cho EH,Lockett S,Dunlop NM,Wang JM
Thu Feb 01 00:00:00 EST 2007
Regulation of reactive oxygen species by Atm is essential for proper response to DNA double-strand breaks in lymphocytes.
Journal of immunology (Baltimore, Md. : 1950)
Ito K,Takubo K,Arai F,Satoh H,Matsuoka S,Ohmura M,Naka K,Azuma M,Miyamoto K,Hosokawa K,Ikeda Y,Mak TW,Suda T,Hirao A
Mon Jan 01 00:00:00 EST 2007
IL-6 plays a unique role in initiating c-Maf expression during early stage of CD4 T cell activation.
Journal of immunology (Baltimore, Md. : 1950)
Yang Y,Ochando J,Yopp A,Bromberg JS,Ding Y
Tue Mar 01 00:00:00 EST 2005
