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产品信息
210-12P80H-100UG
产品规格
已发表种属
Mouse
Expression System
HEK293 cells
分类
Recombinant
类型
Protein
偶联物
形式
Lyophilized
保存条件
-20°C
运输条件
Ambient
产品详细信息
210-12P80H-100UG will be provided as 2 x 50 µg (210-12P80H-50UG).
210-12P80H-1MG will be provided as 20 x 50 µg (210-12P80H-50UG).
210-12P80H-250UG will be provided as 5 x 50 µg (210-12P80H-50UG).
210-12P80H-500UG will be provided as 5 x 100 µg (210-12P80H-50UG).
Recombinant Murine IL-12 p80 is an 80.0 kDa, disulfide linked homodimer of two p40 chains of IL-12 that consists of 626 amino acid residues and less than 5% of the IL-12 p40 monomer.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
靶标信息
IL-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicates that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23, or it can form the homodimer designated IL-12 p80. Elevated levels of IL-12 p80 correlate to macrophage recruitment and increased inflammation in asthma and respiratory viral infection models.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
