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产品信息
PRC1066
应用
建议稀释比
已发表文章
产品规格
种属
Rat
Expression System
E. coli
氨基酸序列
APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK
分子量
7.8 kDa
分类
Recombinant
类型
Protein
纯度
>98% by SDS-PAGE
内毒素浓度
<0.1 ng/µg
活性
ED50 = 10 - 100 ng/mL; determined by the dose-dependent chemotaxis of rat neutrophils.
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
4° C
运输条件
Wet ice (domestic); Wet or Dry ice (international)
产品详细信息
Carrier-Free
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Recombinant rat GRO should be reconstituted in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Recombinant rat GRO is also soluble in most buffered solutions. Further dilutions should be made in buffered solution with carrier protein such as PBS with 1% BSA.
Storage: This lyophilized preparation is stable at 2°C to 8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2°C to 8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeated freeze/thaw cycles.
靶标信息
CXCL1, CXCL2, and CXCL3, also known respectively as GRO alpha, GRO beta (MIP-2 alpha) and GRO gamma (MIP-2 beta), are members of the CXC subfamily of chemokines. Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are potent neutrophil attractants and activators. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 1; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); CINC-1; CXC; CXC motif chemokine; CXCL; CXCL-1; Cytokine-induced neutrophil chemoattractant 1; gro; GRO a; GRO α; GROalpha; Growth-regulated alpha protein; GROα; NAP3; Platelet-derived growth factor-inducible protein KC
基因别名: CINC-1; Cinc1; Cxcl1; Gro; Gro1; Scyb1
UniProt ID: (Rat) P14095
Entrez Gene ID: (Rat) 81503
