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The Human ADAM9 ELISA quantitates Hu ADAM9 in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu ADAM9.
原理方法
The Human ADAM9 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : ADAM9, CORD9, KIAA0021, MCMP, MDC9, MLTNG
基因ID : (Human) 8754
基因符号 : ADAM9
蛋白别名 : a disintegrin and metalloproteinase, ADAM, ADAMs, MDC 9, metalloendopeptidases, OTTHUMP00000216481, OTTHUMP00000216484, OTTHUMP00000216485, ADAM 9, ADAM metallopeptidase domain 9 (meltrin gamma), Cellular disintegrin-related protein, cone rod dystrophy 9, Disintegrin and metalloproteinase domain-containing protein 9, Meltrin-gamma, Metalloprotease/disintegrin/cysteine-rich protein 9, Myeloma cell metalloproteinase
UniProt ID (Human) Q13443