Tau ELISA Kits

ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Tau are available for Human and Mouse which can be quantified in various samples, including supernatant, cerebrospinal fluid, cell lysate, brain homogenate, plasma.

... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Tau are available for Human and Mouse which can be quantified in various samples, including supernatant, cerebrospinal fluid, cell lysate, brain homogenate, plasma.

Invitrogen ELISA kits exist in two formats: Uncoated and... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Tau are available for Human and Mouse which can be quantified in various samples, including supernatant, cerebrospinal fluid, cell lysate, brain homogenate, plasma.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Tau are available for Human and Mouse which can be quantified in various samples, including supernatant, cerebrospinal fluid, cell lysate, brain homogenate, plasma.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits are ready-to-use and quality tested for sensitivity, specificity, precision and lot-to-lot consistency.

Tau detection is also available using highly-sensitive ProQuantum Immunoassays. These assays provide a fast, easy workflow with no wash steps, and are detectable with any real-time PCR instrument.

Can't find what you're looking for? Try the ELISA Builder to design your own assay based on target type and experimental needs. We also offer custom ELISA development services.

靶标信息

Tau is a neuronal microtubule-associated protein found predominantly on axons. The function of Tau is to promote tubulin polymerization and stabilize microtubules. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization. In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain. Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, ultimately leading to the degeneration of the affected neurons. Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II. Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

同义词

AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Tau ELISA Kits

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