Product References
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
Cell
Tracy TE,Madero-Pérez J,Swaney DL,Chang TS,Moritz M,Konrad C,Ward ME,Stevenson E,Hüttenhain R,Kauwe G,Mercedes M,Sweetland-Martin L,Chen X,Mok SA,Wong MY,Telpoukhovskaia M,Min SW,Wang C,Sohn PD,Martin J,Zhou Y,Luo W,Trojanowski JQ,Lee VMY,Gong S,Manfredi G,Coppola G,Krogan NJ,Geschwind DH,Gan L
A-21355 was used in Proximity Ligation Assay (PLA) to demonstrate Tau’s role in neuronal function and disease and highlight potential therapeutic targets to block Tau-mediated pathogenesis.
Thu Feb 17 00:00:00 EST 2022
GRP78 Overexpression Triggers PINK1-IP3R-Mediated Neuroprotective Mitophagy.
Biomedicines
Leiva-Rodríguez T,Romeo-Guitart D,Herrando-Grabulosa M,Muñoz-Guardiola P,Polo M,Bañuls C,Petegnief V,Bosch A,Lizcano JM,Apostolova N,Forés J,Casas C
A-21355 was used in Immunohistochemistry (Frozen) to study how the overexpression of GRP78 promoted motoneuronal neuroprotection after root avulsion by carrying out a comparative unbiased proteomic analysis and pharmacological and genetic interventions.
Wed Aug 18 00:00:00 EDT 2021
GRP78 Overexpression Triggers PINK1-IP3R-Mediated Neuroprotective Mitophagy.
Biomedicines
Leiva-Rodríguez T,Romeo-Guitart D,Herrando-Grabulosa M,Muñoz-Guardiola P,Polo M,Bañuls C,Petegnief V,Bosch A,Lizcano JM,Apostolova N,Forés J,Casas C
A-21355 was used in Immunohistochemistry (Frozen) to study how the overexpression of GRP78 promoted motoneuronal neuroprotection after root avulsion by carrying out a comparative unbiased proteomic analysis and pharmacological and genetic interventions.
Wed Aug 18 00:00:00 EDT 2021
Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome.
Frontiers in cell and developmental biology
Gella A,Prada-Dacasa P,Carrascal M,Urpi A,González-Torres M,Abian J,Sanz E,Quintana A
A-21355 was used in Western Blotting to show a marked reduction of complex I N-module subunit abundance and an increase in the levels of the assembly factor NDUFA2.
Mon Sep 28 00:00:00 EDT 2020
Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome.
Frontiers in cell and developmental biology
Gella A,Prada-Dacasa P,Carrascal M,Urpi A,González-Torres M,Abian J,Sanz E,Quintana A
A-21355 was used in Western Blotting to show a marked reduction of complex I N-module subunit abundance and an increase in the levels of the assembly factor NDUFA2.
Mon Sep 28 00:00:00 EDT 2020
OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation.
Nature communications
Sharanek A,Burban A,Laaper M,Heckel E,Joyal JS,Soleimani VD,Jahani-Asl A
Published figure using ATPIF1 monoclonal antibody (Product # A-21355) in Immunocytochemistry
Mon Aug 17 00:00:00 EDT 2020
OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation.
Nature communications
Sharanek A,Burban A,Laaper M,Heckel E,Joyal JS,Soleimani VD,Jahani-Asl A
Published figure using ATPIF1 monoclonal antibody (Product # A-21355) in Immunocytochemistry
Mon Aug 17 00:00:00 EDT 2020
Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release.
JCI insight
Obata Y,Kita S,Koyama Y,Fukuda S,Takeda H,Takahashi M,Fujishima Y,Nagao H,Masuda S,Tanaka Y,Nakamura Y,Nishizawa H,Funahashi T,Ranscht B,Izumi Y,Bamba T,Fukusaki E,Hanayama R,Shimada S,Maeda N,Shimomura I
A-21355 was used in Immunocytochemistry-immunoflourescence to demonstrate that the adiponectin/T-cadherin system enhances exosome biogenesis and secretion, leading to the decrease of cellular ceramides.
Thu Apr 19 00:00:00 EDT 2018
Endosome-mitochondria interactions are modulated by iron release from transferrin.
The Journal of cell biology
Das A,Nag S,Mason AB,Barroso MM
A21355 was used in immunocytochemistry to study the interactions between transferrin-containing endosomes and mitochondria in epithelial cells
Mon Sep 26 00:00:00 EDT 2016
GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge.
Molecular biology of the cell
Xing M,Peterman MC,Davis RL,Oegema K,Shiau AK,Field SJ
A21355 was used in immunocytochemistry to investigate the role of the phosphatidylinositol-4-phosphate/GOLPH3/myosin 18A/F-actin pathway to directional cell migration
Thu Dec 01 00:00:00 EST 2016
IF1, a natural inhibitor of mitochondrial ATP synthase, is not essential for the normal growth and breeding of mice.
Bioscience reports
Nakamura J,Fujikawa M,Yoshida M
A-21355 was used in Immunocytochemistry-immunoflourescence to establish that IF1 is not an essential protein for mice despite its ubiquitous presence in eukaryotes.
Tue Sep 17 00:00:00 EDT 2013
Equine chorionic gonadotropin alters luteal cell morphologic features related to progesterone synthesis.
Theriogenology
Rigoglio NN,Fátima LA,Hanassaka JY,Pinto GL,Machado AS,Gimenes LU,Baruselli PS,Rennó FP,Moura CE,Watanabe IS,Papa PC
A-21355 was used in immunohistochemistry (paraffin) to test if eCG alters the content of luteal cells and mitochondria related to hormone production.
Fri Mar 01 00:00:00 EST 2013
Arenavirus infection induces discrete cytosolic structures for RNA replication.
Journal of virology
Baird NL,York J,Nunberg JH
A-21355 was used in western blot to identify and study cytosolic structures involved in arenavirus replication and transcription.
Mon Oct 01 00:00:00 EDT 2012
Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses.
DNA repair
Lauritzen KH,Cheng C,Wiksen H,Bergersen LH,Klungland A
A-21355 was used in immunohistochemistry - paraffin section to investigate the effects of mitochondrial DNA damage on hippocampal neurons.
Fri Jun 10 00:00:00 EDT 2011