POROS™ CaptureSelect™ C1-InhXL Affinity Resin
POROS™ CaptureSelect™ C1-InhXL Affinity Resin
Thermo Scientific™

POROS™ CaptureSelect™ C1-InhXL Affinity Resin

Thermo Scientific™ POROS™ CaptureSelect™ C1-InhXL Affinity Resin is intended for the purification of human C1 esterase inhibitor from recombinant and plasma/serum sources.
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货号数量
A6543625 mL
A6543750 mL
A65439250 mL
A654401 L
A654415 L
A6544210 L
货号 A65436
价格(CNY)/ Each
价格29,000.00
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数量:
25 mL
价格(CNY)/ Each
价格29,000.00
添加至购物车
POROS™ CaptureSelect™ C1-InhXL Affinity Resin
货号A65436
价格(CNY)/ Each
价格29,000.00
-
添加至购物车

POROS CaptureSelect C1-InhXL Affinity Resin is intended for the purification of human C1 esterase inhibitor from recombinant and plasma/serum sources. C1 esterase inhibitor is a protease inhibitor belonging to the serpin superfamily that inhibits the spontaneous activation of the complement system. The CaptureSelect C1-InhXL affinity ligand is highly selective for human C1 inhibitor and coupled to the high-performing POROS resin, allowing for an efficient and scalable purification process, with high purity and yield obtained in a single step. The large pore structure of the POROS beads enables higher flowrates and efficient binding of larger biomolecules.

Features of POROS CaptureSelect C1-InhXL Affinity Resin include:

  • Efficient purification of C1 esterase inhibitor with high yield
  • Mild pH elution condition to retain activity
  • High binding capacity at high flow rates
  • Excellent scalability
  • Non-animal derived

Free of animal components

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

Main characteristics

  • Resin: cross-linked poly(styrene-divinylbenzene) POROS beads
  • Average particle size: 50 μm
  • Ligand: single-domain [VHH] antibody fragment
  • Binding capacity: 20–25 g C1-Inhibitor/L resin
  • Elution conditions: 50 mM sodium acetate, 1.0 M MgCl2, pH 5.0
  • Regeneration conditions: acidic stripping condition with 0.5 M acetic acid, pH 2
  • Mechanical resistance: 100 bar (1450 psi, 10 MPa)
  • Formulation buffer: 18% (v/v) ethanol
仅供科研使用。不可用于诊断程序。
规格
结合功能20 to 25 g C1-Inhibitor/L resin
运输条件Wet Ice
粒径50 μm
形式树脂浆液
产品线POROS™ CaptureSelect™
数量25 mL
适用于(应用)Protein purification
靶标C1 Esterase Inhibitor
类型Affinity Resin
Unit SizeEach
内容与储存
Store at 2°C to 8°C.