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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • COX4 Antibodies

          Invitrogen

          COX4 Monoclonal Antibody (K.473.4)

          Advanced Verification
          6 Published Figures
          18 References
          View all (35) COX4 antibodies

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          Cite COX4 Monoclonal Antibody (K.473.4)

          • Antibody Testing Data (5)
          • Published Figures (6)
          • Advanced Verification (1)
          COX4 Antibody in Immunocytochemistry (ICC/IF)
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          COX4 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 12

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          COX4 Antibody (MA5-15078) in ICC/IF

          Immunofluorescent analysis of COX IV in HeLa cells using a COX IV monoclonal antibody (Product # MA5-15078) (green). Actin filaments are labeled with a fluorescent red phalloidin. DNA is labeled using a fluorescent blue dye. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          COX4 Antibody in Immunocytochemistry (ICC/IF)
          COX4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          COX4 Antibody in Western Blot (WB)
          COX4 Antibody in Western Blot (WB)
          COX4 Antibody in Western Blot (WB)
          COX4 Antibody in Immunocytochemistry (ICC/IF)
          COX4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          COX4 Antibody in Western Blot (WB)
          COX4 Antibody in Western Blot (WB)
          COX4 Antibody in Western Blot (WB)
          COX4 Antibody in Western Blot (WB)
          COX4 Antibody
          COX4 Monoclonal Antibody (K.473.4)

          Product Details

          MA5-15078

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          View 11 publications 11 publications

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:2,000
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          1:200-1:800
          View 4 publications 4 publications

          Flow Cytometry (Flow)

          1:400-1:1,600
          -

          Immunoprecipitation (IP)

          1:100
          -

          Affinity Purification (AP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Bovine, Human, Non-human primate, Pig, Rat, Zebrafish

          Published species

          C. elegans, Human, Mouse, Non-human primate, Rat, Rhesus monkey

          Host/Isotype

          Rabbit / IgG

          Class

          Monoclonal

          Type

          Antibody

          Clone

          K.473.4

          Immunogen

          Synthetic peptide corresponding to residues surrounding Lys29 of human COX IV
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          331 µg/mL

          Purification

          Antigen affinity chromatography, Protein A

          Storage buffer

          0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

          Contains

          <0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10987478

          Product Specific Information

          It is not recommended to aliquot this antibody.

          Target Information

          Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX4 (COX4I1) is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: cox iv; COX IV-1; Cox4-1; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; cytochrome c oxidase subunit IV; Cytochrome c oxidase subunit IV isoform 1; cytochrome c oxidase subunit IV precursor EC 1.9.3.1; cytochrome c oxidase, subunit 4a; cytochrome c oxidase, subunit IV; cytochrome c oxidase, subunit IVa; cytochrome c oxydase subunit 4; FLJ23483; MGC72016

          View more View less

          Gene Aliases: COX IV-1; COX4; COX4-1; Cox4a; COX4I1; COXIV; COXIV-1; mg:bb02d03; zgc:110058

          View more View less

          UniProt ID: (Bovine) P00423, (Human) P13073, (Rat) P10888

          View more View less

          Entrez Gene ID: (Bovine) 281090, (Human) 1327, (Pig) 100624067, (Rat) 29445, (Zebrafish) 326975

          View more View less

          Function(s)
          cytochrome-c oxidase activity protein binding oxidase
          Process(es)
          hydrogen ion transmembrane transport generation of precursor metabolites and energy mitochondrial electron transport, cytochrome c to oxygen response to nutrient response to hypoxia
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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