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Application
FIGURE: 1 / 3
ACADL Antibody (PA5-109332) in IHC (P)
Immunohistochemistry analysis of ACADL in paraffin-embedded human kidney tissue. Samples were heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4, 20 minutes) and blocked in 5% BSA (30 min, room temperature), incubated with ACADL polyclonal antibody (Product # PA5-109332) at a dilution of 1:50 (30 min, room temperature), and followed by HRP conjugate, DAB and hematoxylin (mounted with DPX).
Product Details
PA5-109332
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein within Human ACADL aa 218-430
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2854743
Product Specific Information
Positive Control: SH-SY5Y cell, human kidney tissue, F9.
Target Information
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acyl-Coenzyme A dehydrogenase, long chain; LCAD; Long-chain specific acyl-CoA dehydrogenase, mitochondrial
Gene Aliases: ACAD4; ACADL; LCAD
UniProt ID: (Human) P28330
Entrez Gene ID: (Human) 33
temperature homeostasis
fatty acid beta-oxidation
carnitine metabolic process, CoA-linked
fatty acid beta-oxidation using acyl-CoA dehydrogenase
carnitine catabolic process
long-chain fatty acid catabolic process
cellular lipid catabolic process
negative regulation of fatty acid biosynthetic process
negative regulation of fatty acid oxidation
protein homotetramerization
lipid homeostasis
oxidation-reduction process
regulation of cholesterol metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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