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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SOX10 Antibodies

          Invitrogen

          SOX10 Polyclonal Antibody

          View all (49) SOX10 antibodies

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          Cite SOX10 Polyclonal Antibody

          • Antibody Testing Data (1)
          SOX10 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          SOX10 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          SOX10 Antibody (PA5-112860) in WB

          Western Blot analysis of SOX10 in Recombinant protein using a SOX10 polyclonal antibody (Product # PA5-112860) at a concentration of 3.4 µg/ml. A goat anti rabbit polyclonal secondary antibody was used at a dilution of 1:50,000. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SOX10 Antibody in Western Blot (WB)

          Product Details

          PA5-112860

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:5,000
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Zebrafish

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Zebrafish HMG-box transcription factor Sox10 protein (1-485AA)

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          5 mg/mL

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.03% ProClin 300

          Storage conditions

          -20°C or -80°C if preferred

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2867594

          Target Information

          SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: cls; colorless; colourless; colourless/sox10; golas; gos; MGC15649; sox10b; SRY; SRY (sex determining region Y)-box 10; SRY-box containing gene 10

          View more View less

          Gene Aliases: cls/sox10; zgc:100757

          View more View less

          Entrez Gene ID: (Zebrafish) 140616

          View more View less

          Function(s)
          core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter neural crest cell migration morphogenesis of an epithelium peripheral nervous system development glial cell differentiation positive regulation of gene expression neural crest cell development Schwann cell differentiation Schwann cell development olfactory bulb development glial cell development myelination in peripheral nervous system melanocyte differentiation pigmentation positive regulation of transcription from RNA polymerase II promoter developmental pigmentation enteric nervous system development oligodendrocyte differentiation semicircular canal morphogenesis inner ear development otolith development negative regulation of neurogenesis pigment cell differentiation retina development in camera-type eye otic vesicle morphogenesis cranial skeletal system development
          It has to be done as per old AB suggested Products section.
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