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COQ6 (Coenzyme Q10 monooxygenase 6) is also named as CGI-10 and belongs to the ubiH/COQ6 family. It is an evolutionarily conserved flavin-dependent monooxygenase required for biosynthesis of coenzyme Q10, or ubiquinone. It has 3 isoforms with the molecular mass of 51 kDa, 43 kDa and 49 kDa. In inner ear, Coq6 is expressed in spiral ganglion, stria vascularis cells, and spiral ligament. Defects in COQ6 are the cause of coenzyme Q10 deficiency, primary, type 6 (COQ10D6).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Coenzyme Q10 monooxygenase 6; coenzyme Q6 homolog, monooxygenase; coenzyme Q6 monooxygenase; Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial
基因别名: 5930427M12Rik; AW742344; CGI-10; CGI10; COQ10D6; COQ6
UniProt ID: (Human) Q9Y2Z9, (Mouse) Q8R1S0
Entrez Gene ID: (Human) 51004, (Mouse) 217707