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Product Details
PA5-116331
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 82-108 amino acids from the Central region of human TTPA
Conjugate
Unconjugated
Form
Liquid
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2900965
Target Information
This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-tocopherol transfer protein; Alpha-TTP; tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency)
Gene Aliases: alphaTTP; ATTP; AVED; TPP1; TTP1; TTPA
UniProt ID: (Human) P49638
Entrez Gene ID: (Human) 7274
embryonic placenta development
lipid metabolic process
transport
response to nutrient
response to pH
response to toxic substance
vitamin E metabolic process
intermembrane transport
vitamin transport
intracellular pH reduction
negative regulation of cell death
negative regulation of establishment of blood-brain barrier
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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