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Peptide sequence: GSQLGEFWLG NDNIHALTAQ GSSELRVDLV DFEGNHQFAK YKSFKVADEA
Sequence homology: Cow: 85%; Dog: 92%; Guinea Pig: 79%; Horse: 82%; Human: 100%; Mouse: 77%; Pig: 93%; Rat: 86%
M-Ficolin (Ficolin-1) is a non-serum protein that is expressed in leukocytes and lung. M-Ficolin precipitates with mannose-binding lectin (MBL)-associated serine proteases (MASP)-1 and MASP-2, indicating that M-Ficolin forms complexes with MASP-1 and MASP-2, recognizes certain types of bacteria and subsequently activates the lectin pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Collagen/fibrinogen domain-containing protein 1; Ficolin-1; Ficolin-A; Ficolin-alpha; M-ficolin
Gene Aliases: FCN1; FCNM
UniProt ID: (Human) O00602
Entrez Gene ID: (Human) 2219
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