Pierce™ Traut's Reagent (2-iminothiolane)
Pierce™ Traut's Reagent (2-iminothiolane)
Thermo Scientific™

Pierce™ Traut's Reagent (2-iminothiolane)

Thermo Scientific Pierce Traut's Reagent (2-iminothiolane) is a small thiolation compound that reacts with primary amines (e.g., lysine side chains)Read more
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Catalog number 26101
Price (CNY)/ Each
Price:3,244.00
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Quantity:
500 mg
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Price (CNY)/ Each
Price:3,244.00
Add to cart
Pierce™ Traut's Reagent (2-iminothiolane)
Catalog number26101
Price (CNY)/ Each
Price:3,244.00
-
Add to cart
Thermo Scientific Pierce Traut's Reagent (2-iminothiolane) is a small thiolation compound that reacts with primary amines (e.g., lysine side chains) to add a small spacer arm (8.1 angstroms) terminated by a free sulfhydryl group.

Features of Thermo Scientific Pierce Traut's Reagent (2-iminothiolane):

Simple—one-step conversion of amines to sulfhydryls
Specific—selective and spontaneous modification of primary amines at pH 7-10
• Preserves positive charge to maintain protein solubility

Traut's Reagent (2-iminothiolane or 2-IT) is a cyclic thioimidate compound for thiolation (sulfhydryl addition). Traut's Reagent reacts with primary amines (—NH2) to introduce sulfhydryl (—SH) groups while maintaining charge properties similar to the original amino group. Once added, sulfhydryl groups can be specifically targeted for reaction in a variety of useful labeling, crosslinking and immobilization procedures.

Flexible—incorporates a five-atom spacer arm to reduce steric hindrance
Soluble—preserves the original positive charge to preserve protein solubility

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Pierce™ SATA
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityAmine
Label or DyeSulfhydryl Group
Label TypeConjugating Groups
Product LinePierce™
SpacerShort (<10 Å)
FormPowder
Quantity500 mg
SolubilityDMF, DMSO
Product TypeThiophilic Adsorption Kit
Unit SizeEach
Contents & Storage
Storage: Upon receipt store product at 4°C with desiccant. Product shipped at ambient temperature