CaptureSelect™ Factor X Affinity Matrix
CaptureSelect™ Factor X Affinity Matrix
Thermo Scientific™

CaptureSelect™ Factor X Affinity Matrix

Thermo Scientific™ CaptureSelect™ Factor X Affinity Matrix was specifically designed for the purification of human Factor X from plasma and recombinant sources.
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Catalog NumberQuantity
294370205050 mL
29437020055 mL
294370201010 mL
1943702250250 mL
194370201L1 L
194370205L5 L
Catalog number 2943702050
Price (CNY)/ Each
Price:125,741.00
Online offer:100,592.80Web orders only. Excludes Supply Centers.
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Quantity:
50 mL
Price (CNY)/ Each
Online offer:100,592.80Web orders only. Excludes Supply Centers.
Add to cart
CaptureSelect™ Factor X Affinity Matrix
Catalog number2943702050
Price (CNY)/ Each
Online offer:100,592.80Web orders only. Excludes Supply Centers.
-
Add to cart

CaptureSelect Factor X Affinity Matrix was specifically designed for the purification of human Factor X from plasma and recombinant sources.

Features of the CaptureSelect Factor X Affinity Matrix include:

  • Highly selective for human Factor X with no affinity for other human plasma proteins
  • Binds both Factor X and Factor Xa in the presence of calcium
  • Enables efficient purification of Factor X with high yields and retained activity
  • Mild elution at neutral pH using EDTA
  • Offers excellent scalability
  • Non-animal-derived

Coagulation Factor X is a vitamin K-dependent, liver-produced serine protease that serves as the first enzyme in the coagulation cascade to form fibrin. It is a two-chain glycoprotein with a molecular weight of approximately 59 kDa. Factor X normally circulates in the plasma as an inactive molecule with activation of Factor X involved in both the intrinsic and extrinsic coagulation pathways.

Free of animal components

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

Main characteristics

  • Matrix: agarose-based
  • Average particle size: 65 ± 10 μm
  • Ligand: CaptureSelect Factor X affinity ligand
  • Ligand coupling method: epoxide
  • Binding capacity: >10 mg/mL resin
  • Binding conditions: 50 mM Tris, 150 mM NaCl, 5 mM CaCl2, pH 7
  • Elution conditions: 50 mM Tris, 150 mM NaCl, 5 mM EDTA, pH 7
  • Flow characteristics: 50–200 cm/h (up to 2 bar)
  • Formulation buffer: 20% (v/v) ethanol
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Binding Capacity>10 mg/mL
Flow Rate50 to 200 cm/hr. (Up to 2 bar)
MatrixAgarose-based
Shipping ConditionWet Ice
Particle Size65 ±10 μm
FormAgarose Bead
Product LineCaptureSelect™
Quantity50 mL
TargetProtein
TypeAffinity Matrix
Ligand TypeFactor X affinity ligand
Stationary PhaseFactor X
Column TypeAgarose Resin
Unit SizeEach
Contents & Storage
Store in refrigerator (2°C to 8°C).