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Things change rapidly in the business of drug discovery: assay techniques, instrument technologies, bioinformatics, staff, facilities, research goals, government regulations... budgets. The solution is here now: Thermo Scientific™ Dimension4 Modular Automation Platform consists of software and hardware components that enable you to rapidly develop any size of automated lab system, from workstation to production line. Dimension4 provides an automation platform that meets all your needs—flexibility, scalability, reconfigurability, reliability, ultra high throughput, now and for years to come.
Problem: Automate a cellular ion channel assay that requires room temperature storage for both 30 compound sample plates and 30 assay cell plates, simultaneous compound addition to all wells, and whole plate imaging
Solution: Develop a workstation built on a single Dimension4 Modular Table section, two Microplate Hotels, a Robbins Scientific Hydra96 liquid handler, an Applied Biosystems Northstar reader, and a CataLyst-5 plate mover—all controlled by Thermo Scientific Polara software
Problem: Add temperature-controlled incubation for the cell plates and increase your walkaway time
Solution: Connect another Modular Table section and integrate a Thermo Scientific Cytomat series carousel incubator and additional Microplate Hotels
Problem: Suppose that you must add temperature-controlled incubation for the cell plates and increase your walkaway time?
Solution: Connect another Modular Table section and integrate a Thermo Scientific Cytomat series carousel incubator and additional Microplate Hotels
Problem: Expand this application to include automated compound preparation and cell plating functions
Solution: Connect additional Dimension4 Modular Table sections, mount the CataLyst-5 on a linear track, integrate a second liquid handler and additional microplate storage units, and upgrade the Polara software to accommodate the new instrument
Problem: A new bioassay technology requires a different reader and a five-fold increase in microplate throughput
Solution: Rapidly swap readers, and replace the CataLyst-5 with Dimension4 Flip Movers and Linear Plate Transport