CellSensor™ AP-1-bla HEK293T Cell Line
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Thermo Scientific™

CellSensor™ AP-1-bla HEK293T Cell Line

The CellSensor™ AP-1-bla HEK 293T Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stablyRead more
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Catalog number K1658
Price (CNY)/ Each
Price:160,738.00
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Price (CNY)/ Each
Price:160,738.00
Add to cart
CellSensor™ AP-1-bla HEK293T Cell Line
Catalog numberK1658
Price (CNY)/ Each
Price:160,738.00
-
Add to cart

The CellSensor™ AP-1-bla HEK 293T Cell Line contains a beta-lactamase reporter gene under control of the AP-1 response element stably integrated into HEK 293T cells. The cell line was created through sorting by FACS of cells responsive to stimulation of the AP-1 pathway with phorbol 12-myristate 13-acetate (PMA). The cell line was validated for DMSO tolerance, incubation time with stimulant, and substrate loading conditions. The AP-1-bla HEK 293T cell line responds to agonist treatment as expected from literature and can be adapted for high throughput screening for agonists or antagonists of the AP-1 pathway with compound libraries. Candidate drugs can also be tested for dose response against this cell line. Academic and non-profit customers, please inquire for special pricing.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
Assay EntryCell-based beta lactamase reporter gene
Cell StateDividing Cells
Product LineCellSensor™
Quantity1 Vial
Target EntryEGFR, ERK1/2, p38, MEK, MAPK pathway, c-MET, JNK, RON, RAF
System TypeCellSensor™
Druggable TargetSignaling Pathway
Unit SizeEach
Contents & Storage
CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.