Vanquish™ Online 2D-LC Systems

Improve the analysis of complex samples or simplify the separation of difficult-to-resolve analytes with Thermo Scientific™ Vanquish™ Online 2D-LC Systems. Select from one of four configurations focused on online SPE or various heart-cutting two-dimensional liquid chromatography (LC-LC) workflows. The modular instrument can use modules from the Vanquish Core HPLC, Vanquish Flex UHPLC or Vanquish Horizon UHPLC systems, retaining the performance, robustness, and ease of use of the Vanquish platform, while offering maximum application flexibility.

View Vanquish Online 2D-LC resources ∣ HPLC Support Center

Add separation power, gain more information

• Flexible configurations with the modular instrument design to tailor a system for your application needs
• Confidence to confirm peak verification, purity and identity of complex samples by LC-LC
• Smooth adoption of two-dimensional liquid chromatography workflow utilizing downloadable software templates

Vanquish™ Online SPE HPLC and UHPLC Systems
Ensure analyte pre-concentration and sample clean-up in an automated repeatable workflow while saving solvent and time.

Vanquish™ Loop Heart-Cut 2D-LC Systems
Collect one or multiple fractions of the first-dimension separation in a sample loop and transfer the cut-out fraction(s) in an automated workflow to an orthogonal column chemistry for confidence in peak purity.

Vanquish™ Trap Heart-Cut 2D-LC Systems
Transfer single fractions from the first-dimension column to a trap column before transferring to the second dimension column, allowing you to achieve mobile phase compatibility between dimensions to support multiple combinations of ¹D and ²D methods for simplified multi-dimensional liquid chromatography method development.

Vanquish™ Simple Switch™ 2D-LC Systems
For labs looking to do it all in one system, this innovative configuration utilizes the unique Thermo Scientific™ Vanquish™ Dual Split Sampler to efficiently utilize the instrumentation and enable users to seamlessly switch between a Vanquish trap-based heart-cut 2D-LC system and a Thermo Scientific™ Vanquish™ Duo for Dual LC system for confidence and improved productivity within one system.