Thermo Scientific Pierce TSAT is tris-(succinimidyl) aminotriacetate, a novel trifunctional crosslinker that contains three short spacers arms linked to a central nitrogen atom, each ending in an amine-reactive NHS-ester group.
Features of TSAT:
•
Reactive groups: NHS ester (three ends)
•
Reactive towards: amino groups (primary amines)
• NHS ester couples to amines at pH 7-9 form stable amide bonds
• Trifunctional amine-reactive crosslinking agent
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
Applications:• Preparation of multicomponent aggregates
• Polyerization of protein interactions for nearest-neighbor studies
• Core molecule for the construction of dendritic polymers
Product References:Crosslinker Application Guide -- search for recent literature references for this product
Related ProductsTSAT (tris-(succinimidyl)aminotriacetate)