A part of the JAK/STAT Pathway, STAT3 (Signal Transducer and Activator of Transcription 3) is phosphorylated at Tyr705 by the Janus family of tyrosine kinases.
For use in combination with the GFP-STAT3 physiological protein substrate (PV5212) and the LanthaScreen™ STAT3 GripTite™ cell line (K1488) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.
规格
偶联物
Tb (Terbium)/GFP (EmGFP)
数量
1 mg
产品规格
384-well Plate
激发/发射
340⁄490, 520
反应性
Human
运输条件
Dry Ice
读值
End Point
反应性 abrv
Hu
目标酶
Tyrosine Kinases
技术
TR-FRET
已验证激酶
JAK1, JAK2, JAK3, TYK2
内容与储存
Terbium-labeled anti-STAT3 [pTyr705] antibody in HEPES buffered saline. Store at -20°C.