Product References
A semi-automated pipeline for quantifying drusen-like deposits in human induced pluripotent stem cell-derived retinal pigment epithelium cells.
SLAS technology
Hall J,Daniszewski M,Cheung S,Shobhana K,Kumar H,Liang HH,Beetham H,Cho E,Abbott C,Hewitt AW,Simpson KJ,Guymer RH,Paull D,Pébay A,Lidgerwood GE
33-9100 was used in Immunohistochemistry to develop an imaging and analysis pipeline that quantifies the number of drusen-like deposits, and accurately and reproducibly provides the location and composition of these deposits.
Sat Jun 01 00:00:00 EDT 2024
Analyzing Trophoblast Fusion Using Immunofluorescence and Split Protein Complementation Assays.
Methods in molecular biology (Clifton, N.J.)
Jaremek A,Renaud SJ
33-9100 was used in Immunocytochemistry to describe protocols for measuring trophoblast fusion using immunofluorescence and an assay employing complementary parts of a split green fluorescent protein that self-reassociates and generates a fluorescent signal following cell fusion.
Thu Nov 30 00:00:00 EST 2023
CD206+ macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia.
Cell reports
Hattori Y,Kato D,Murayama F,Koike S,Asai H,Yamasaki A,Naito Y,Kawaguchi A,Konishi H,Prinz M,Masuda T,Wake H,Miyata T
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to demonstrate that the "roof plate→ventricle→pallium" route is an essential path for microglial colonization into the embryonic mouse brain.
Tue Feb 28 00:00:00 EST 2023
Sperm morphological abnormalities in autosomal dominant polycystic kidney disease are associated with the Hippo signaling pathway via PC1.
Frontiers in endocrinology
Shi WH,Zhou ZY,Ye MJ,Qin NX,Jiang ZR,Zhou XY,Xu NX,Cao XL,Chen SC,Huang HF,Xu CM
33-9100 was used in Immunocytochemistry to report thirteen ADPKD males with infertility and investigated the sperm morphological defects associated with PC1 disruption.
Thu May 18 00:00:00 EDT 2023
Coxsackievirus B3 infects and disrupts human induced-pluripotent stem cell derived brain-like endothelial cells.
Frontiers in cellular and infection microbiology
Mamana J,Humber GM,Espinal ER,Seo S,Vollmuth N,Sin J,Kim BJ
33-9100 was used in Immunocytochemistry-immunofluorescence to elucidate the unique effects of CVB3 infection on the BBB and shed light on potential mechanisms by which the virus can initiate infections in the brain.
Fri May 05 00:00:00 EDT 2023
A ratchet-like apical constriction drives cell ingression during the mouse gastrulation EMT.
eLife
Francou A,Anderson KV,Hadjantonakis AK
33-9100 was used in Immunocytochemistry-immunofluorescence to show that loss of function analyses demonstrated a requirement for Crumbs2 in myosin II localization and activity at apical junctions, and as a candidate regulator of actomyosin anisotropy.
Wed May 10 00:00:00 EDT 2023
A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip.
Frontiers in pharmacology
Sengupta A,Dorn A,Jamshidi M,Schwob M,Hassan W,De Maddalena LL,Hugi A,Stucki AO,Dorn P,Marti TM,Wisser O,Stucki JD,Krebs T,Hobi N,Guenat OT
33-9100 was used in Immunocytochemistry-immunofluorescence to suggest an important synergistic effect on the air-blood barrier sensitivity, cytotoxicity and inflammation, when air-liquid interface and cyclic stretch culture conditions are combined.
Wed Jun 21 00:00:00 EDT 2023
Regenerative potential and limitations in a zebrafish model of hyperglycemia-induced nerve degeneration.
Developmental dynamics : an official publication of the American Association of Anatomists
Sargent S,Brennan A,Clark JK
33-9100 was used in Immunohistochemistry to optimize the hyperglycemic-induction protocol, characterize deficits in nerve structure and behavioral function, and then examine the regenerative potential following recovery from the hyperglycemic state.
Thu Jun 01 00:00:00 EDT 2023
Mutating novel interaction sites in NRP1 reduces SARS-CoV-2 spike protein internalization.
iScience
Pal D,De K,Yates TB,Kolape J,Muchero W
33-9100 was used in Immunocytochemistry to show that cysteine residues located in the vestigial plasminogen-apple-nematode (PAN) domain of NRP1 are necessary for SARS-CoV-2 spike protein internalization.
Fri Apr 21 00:00:00 EDT 2023
An intrinsic purine metabolite AICAR blocks lung tumour growth by targeting oncoprotein mucin 1.
British journal of cancer
Aftab F,Rodriguez-Fuguet A,Silva L,Kobayashi IS,Sun J,Politi K,Levantini E,Zhang W,Kobayashi SS,Zhang WC
33-9100 was used in Proximity Ligation Assay (PLA) to investigate the inhibitory effects of AICAR on MUC1 activity in EGFR-mutant lung cancer cells.
Mon May 01 00:00:00 EDT 2023
Restorative effects of Lactobacillus rhamnosus LR-32 on the gut microbiota, barrier integrity, and 5-HT metabolism in reducing feather-pecking behavior in laying hens with antibiotic-induced dysbiosis.
Frontiers in microbiology
Huang C,Yue Q,Sun L,Di K,Yang D,Hao E,Wang D,Chen Y,Shi L,Zhou R,Zhao G,Chen H
33-9100 was used in Western Blot to indicate that dietary supplementation with Lactobacillus rhamnosus LR-32 can reduce antibiotic-induced FP in laying hens and is a promising treatment to improve the welfare of domestic birds.
Wed Sep 20 00:00:00 EDT 2023
Wnt9 directs zebrafish heart tube assembly via a combination of canonical and non-canonical pathway signaling.
Development (Cambridge, England)
Paolini A,Sharipova D,Lange T,Abdelilah-Seyfried S
33-9100 was used in Immunohistochemistry to demonstrate how these morphogens activate a combination of downstream pathways to direct cardiac morphogenesis.
Fri Sep 15 00:00:00 EDT 2023
Usefulness of a humanized tricellular static transwell blood-brain barrier model as a microphysiological system for drug development applications. - A case study based on the benchmark evaluations of blood-brain barrier microphysiological system.
Regenerative therapy
Nakayama-Kitamura K,Shigemoto-Mogami Y,Toyoda H,Mihara I,Moriguchi H,Naraoka H,Furihata T,Ishida S,Sato K
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to provide the SOPs with the flow chart including entire procedure and how to apply each SOP.
Wed Mar 01 00:00:00 EST 2023
Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids.
Nature microbiology
Rybak-Wolf A,Wyler E,Pentimalli TM,Legnini I,Oliveras Martinez A,Glažar P,Loewa A,Kim SJ,Kaufer BB,Woehler A,Landthaler M,Rajewsky N
33-9100 was used in Immunohistochemistry (Frozen) to characterize HSV-1 infection of human brain organoids by combining single-cell RNA sequencing, electrophysiology and immunostaining.
Sat Jul 01 00:00:00 EDT 2023
Functional Blood-Brain Barrier Model with Tight Connected Minitissue by Liquid Substrates Culture.
Advanced healthcare materials
Liu N,Zhu Y,Yu K,Gu Z,Lv S,Chen Y,He C,Fu J,He Y
33-9100 was used in Immunocytochemistry to present a new blood-brain barrier (BBB) model with a high-cell spatial density and tightly connected biomimetic minitissue.
Wed Feb 01 00:00:00 EST 2023
Corneal Edema in Inducible Slc4a11 Knockout Is Initiated by Mitochondrial Superoxide Induced Src Kinase Activation.
Cells
Ogando DG,Kim ET,Li S,Bonanno JA
33-9100 was used in Simple Western - Size to investigate the link between oxidative stress and the failure of pump and barrier functions and to test different approaches to revert the process.
Thu Jun 01 00:00:00 EDT 2023
Corneal Edema in Inducible Slc4a11 Knockout Is Initiated by Mitochondrial Superoxide Induced Src Kinase Activation.
Cells
Ogando DG,Kim ET,Li S,Bonanno JA
33-9100 was used in Simple Western - Size to investigate the link between oxidative stress and the failure of pump and barrier functions and to test different approaches to revert the process.
Thu Jun 01 00:00:00 EDT 2023
A platform to reproducibly evaluate human colon permeability and damage.
Scientific reports
Marr EE,Mulhern TJ,Welch M,Keegan P,Caballero-Franco C,Johnson BG,Kasaian M,Azizgolshani H,Petrie T,Charest J,Wiellette E
33-9100 was used in Immunocytochemistry-immunofluorescence to develop an Inflammatory Bowel Disease-relevant model through cytokine induced damage that can support studies of disease mechanisms and putative therapeutics.
Thu Jun 01 00:00:00 EDT 2023
The pro-inflammatory response to influenza A virus infection is fueled by endothelial cells.
Life science alliance
Bauer L,Rijsbergen LC,Leijten L,Benavides FF,Noack D,Lamers MM,Haagmans BL,de Vries RD,de Swart RL,van Riel D
33-9100 was used in Immunocytochemistry to show that LMECs are abortively infected by IAV but can fuel the inflammatory response.
Sat Jul 01 00:00:00 EDT 2023
Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration.
Nature methods
Song MJ,Quinn R,Nguyen E,Hampton C,Sharma R,Park TS,Koster C,Voss T,Tristan C,Weber C,Singh A,Dejene R,Bose D,Chen YC,Derr P,Derr K,Michael S,Barone F,Chen G,Boehm M,Maminishkis A,Singec I,Ferrer M,Bharti K
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to engineer a native-like three-dimensional (3D) oBRB tissue (3D-oBRB) by bioprinting endothelial cells, pericytes, and fibroblasts on the basal side of a biodegradable scaffold and establishing an RPE monolayer on top.
Sun Jan 01 00:00:00 EST 2023
S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung.
Acta pharmaceutica Sinica. B
Hao M,Fu R,Tai J,Tian Z,Yuan X,Chen Y,Wang M,Jiang H,Ji M,Lai F,Xue N,Bai L,Zhu Y,Lv X,Chen X,Jin J
33-9100 was used in Immunocytochemistry to suggest that S1PR1 might be a promising drug target for IPF therapy.
Wed Mar 01 00:00:00 EST 2023
Angiotensin receptor blockade with olmesartan alleviates brain pathology in obese OLETF rats.
Clinical and experimental pharmacology & physiology
Rodriguez-Ortiz CJ,Thorwald MA,Rodriguez R,Mejias-Ortega M,Kieu Z,Maitra N,Hawkins C,Valenzuela J,Peng M,Nishiyama A,Ortiz RM,Kitazawa M
33-9100 was used in Western Blotting to demonstrate that the progression of MetS in OLETF rats is associated with deterioration of various aspects of neuronal integrity that may manifest neurodegenerative conditions and that overactivation of angiotensin receptor directly or indirectly contributes to these detriments.
Wed Mar 01 00:00:00 EST 2023
Angiotensin receptor blockade with olmesartan alleviates brain pathology in obese OLETF rats.
Clinical and experimental pharmacology & physiology
Rodriguez-Ortiz CJ,Thorwald MA,Rodriguez R,Mejias-Ortega M,Kieu Z,Maitra N,Hawkins C,Valenzuela J,Peng M,Nishiyama A,Ortiz RM,Kitazawa M
33-9100 was used in Western Blotting to demonstrate that the progression of MetS in OLETF rats is associated with deterioration of various aspects of neuronal integrity that may manifest neurodegenerative conditions and that overactivation of angiotensin receptor directly or indirectly contributes to these detriments.
Wed Mar 01 00:00:00 EST 2023
Xanthine oxidase, a therapeutic target of realgar for non-small cell lung cancer.
Heliyon
Guo R,Gong X,Li K,Qiu Z,Yang L,Wan Y,Yao X,Long C,Xu J,Li K,Liu J,Liu J
33-9100 was used in Western Blotting to identify the molecular targets of realgar against NSCLC and explore their therapeutic mechanisms based on a network pharmacology approach and experimental validations.
Sun Jan 01 00:00:00 EST 2023
Tau tubulin kinase 1 and 2 regulate ciliogenesis and human pluripotent stem cells-derived neural rosettes.
Scientific reports
Binó L,Čajánek L
33-9100 was used in Immunocytochemistry-immunofluorescence to analyze the consequences of primary cilia modulation for human pluripotent stem cells (hPSCs) proliferation and differentiation.
Wed Aug 09 00:00:00 EDT 2023
Micromolded honeycomb scaffold design to support the generation of a bilayered RPE and photoreceptor cell construct.
Bioactive materials
Lee IK,Xie R,Luz-Madrigal A,Min S,Zhu J,Jin J,Edwards KL,Phillips MJ,Ludwig AL,Gamm DM,Gong S,Ma Z
33-9100 was used in Immunocytochemistry-immunofluorescence to develop microfabricated, honeycomb-patterned, biodegradable poly(glycerol sebacate) (PGS) scaffolds to deliver organized, adjacent layers of RPE and PRs to the subretinal space.
Fri Dec 01 00:00:00 EST 2023
Derivation of Sendai-Virus-Reprogrammed Human iPSCs-Neuronal Precursors: In Vitro and In Vivo Post-grafting Safety Characterization.
Cell transplantation
Shigyo M,Kobayashi Y,Platoshyn O,Marsala S,Kato T,Takamura N,Yoshida K,Kishino A,Bravo-Hernandez M,Juhas S,Juhasova J,Studenovska H,Proks V,Ciacci JD,Marsala M
33-9100 was used in Flow cytometry/Cell sorting to demonstrate the effective use of in vitro manual-selection protocol to generate safe and expandable NPCs from hiPSCs cells.
Mon Mar 27 00:00:00 EDT 2023
The Effect of High Molecular Weight Hyaluronic Acid and Latanoprost Eyedrops on Tear Functions and Ocular Surface Status in C57/BL6 Mice.
Journal of clinical medicine
Dogru M,Kojima T,Higa K,Igarashi A,Kudo H,Müller-Lierheim WGK,Tsubota K,Negishi K
33-9100 was used in Immunohistochemistry to show that Comfort Shield (CS) + Latanoprost (LP) formulation appeared to induce less inflammation, less corneal vital staining, and a better barrier status with an IOP lowering effect comparable to the commercial LP eye drops.
Mon Jan 09 00:00:00 EST 2023
A foundational approach to culture and analyze malnourished organoids.
Gut microbes
Perlman M,Senger S,Verma S,Carey J,Faherty CS
33-9100 was used in Immunohistochemistry to evaluate the effect of malnourishment on barrier formation and the ability of the bacterial pathogen Shigella flexneri to infect the GI epithelium.
Fri Dec 01 00:00:00 EST 2023
An in vitro model for vitamin A transport across the human blood-brain barrier.
eLife
Est CB,Murphy RM
33-9100 was used in Immunocytochemistry to describe herein provide a platform for deeper exploration of the regulatory mechanisms of retinol trafficking to the human brain.
Tue Nov 07 00:00:00 EST 2023
An in vitro model for vitamin A transport across the human blood-brain barrier.
eLife
Est CB,Murphy RM
33-9100 was used in Immunocytochemistry to describe herein provide a platform for deeper exploration of the regulatory mechanisms of retinol trafficking to the human brain.
Tue Nov 07 00:00:00 EST 2023
Nuclear export inhibition jumbles epithelial-mesenchymal states and gives rise to migratory disorder in healthy epithelia.
eLife
Krull CM,Li H,Pathak A
33-9100 was used in Immunocytochemistry-immunofluorescence to propose an expanded E-M model, which may help further understand fundamental biological phenomena and inform pathological treatments.
Tue Feb 21 00:00:00 EST 2023
Cell cycle dynamics control fluidity of the developing mouse neuroepithelium.
Nature physics
Bocanegra-Moreno L,Singh A,Hannezo E,Zagorski M,Kicheva A
33-9100 was used in Immunohistochemistry to find that at early developmental stages, the epithelium in the developing mouse spinal cord maintains both high junctional tension and high fluidity.
Thu Sep 28 00:00:00 EDT 2023
Monitoring Effects of Membrane Traffic Via Changes in Cell Polarity and Morphogenesis in Three-Dimensional Human Pluripotent Stem Cell Cysts.
Methods in molecular biology (Clifton, N.J.)
Hamed MM,Taniguchi K,Duncan MC
33-9100 was used in Immunohistochemistry, ELISA, Immunocytochemistry, Western Blot to generate hPSC-cysts, a 3-D hPSC-based model of human epiblast lumen formation, which provides unique opportunities to examine the role of membrane traffic during epithelial morphogenesis.
Thu Dec 15 00:00:00 EST 2022
Establishing an Efficient Electroporation-Based Method to Manipulate Target Gene Expression in the Axolotl Brain.
Cell transplantation
Fu S,Peng C,Zeng YY,Qiu Y,Liu Y,Fei JF
33-9100 was used in Immunohistochemistry to establish a rapid and efficient electroporation-based gene manipulation approach allowing for investigation of gene function in the process of axolotl brain regeneration.
Thu Nov 02 00:00:00 EDT 2023
Defined Differentiation of Human Pluripotent Stem Cells to Brain Microvascular Endothelial-Like Cells for Modeling the Blood-Brain Barrier.
Methods in molecular biology (Clifton, N.J.)
Foreman KL,Shusta EV,Palecek SP
33-9100 was used in Immunocytochemistry to provide a detailed, step-by-step protocol for differentiation of human pluripotent stem cells (hPSCs) to cells exhibiting key characteristics of BMECs, including paracellular and transcellular transport resistance and transporter function that enable modeling the human BBB.
Mon Jun 12 00:00:00 EDT 2023
HNF1β-associated cyst development and electrolyte disturbances are not explained by BAIAP2L2 expression.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Tholen LE,Schigt H,Kleuskens SGE,Bos C,Spruijt CG,Willemsen B,Vermeulen M,Hoenderop JGJ,de Baaij JHF
33-9100 was used in Immunocytochemistry to report that mice lacking BAIAP2L2.
Sun Jan 01 00:00:00 EST 2023
A mechanism of melanogenesis mediated by E-cadherin downregulation and its involvement in solar lentigines.
International journal of cosmetic science
Inoue D,Narita T,Ono T,Ishikawa K,Maeno K,Aoki H,Motoyama A,Shibata T
33-9100 was used in Immunocytochemistry to show that E-cadherin downregulation triggers various downstream melanocytic processes, such as the secretion of melanocytic factors and melanogenesis.
Fri Dec 01 00:00:00 EST 2023
Brain blood vessel autoantibodies in patients with NMDA and GABAA receptor encephalitis: identification of unconventional Myosin-X as target antigen.
Frontiers in cellular neuroscience
Li LY,Kreye J,Burek M,Cordero-Gomez C,Barthel PC,Sánchez-Sendín E,Kornau HC,Schmitz D,Scharf M,Meybohm P,Reincke SM,Prüss H,Höltje M
33-9100 was used in Western Blotting to conclude that autoantibodies to blood vessels occur in autoimmune encephalitis patients and might contribute to a disruption of the blood-brain barrier thereby suggesting a potential pathophysiological relevance of these antibodies.
Fri Feb 17 00:00:00 EST 2023
Comparative Expression Profiling Reveals the Regulatory Effects of Dietary Mannan Oligosaccharides on the Intestinal Immune Response of Juvenile Megalobrama amblycephala against Aeromonas hydrophila Infection.
International journal of molecular sciences
Zhao X,Wang X,Li H,Liu Y,Zheng Y,Li H,Zhang M,Cheng H,Xu J,Chen X,Ding Z
33-9100 was used in Western Blot to clarify the regulatory mechanism of MOS on the intestinal immunity of M. amblycephala and lay the theoretical foundation for the prevention and protection of fish bacterial diseases.
Sun Jan 22 00:00:00 EST 2023
Normal saline remodels the omentum and stimulates its receptivity for transcoelomic metastasis.
JCI insight
Akasaka H,Lee W,Ko SY,Lengyel E,Naora H
33-9100 was used in Immunocytochemistry-immunofluorescence to suggest that normal saline stimulates the receptivity of the omentum for cancer cells and that the risk of colonization can be minimized by using a biocompatible crystalloid for lavage procedures.
Thu Jun 22 00:00:00 EDT 2023
Intestinal vitamin D receptor protects against extraintestinal breast cancer tumorigenesis.
Gut microbes
Zhang YG,Xia Y,Zhang J,Deb S,Garrett S,Sun J
33-9100 was used in Immunohistochemistry to provide insights into the mechanism by which intestinal VDR dysfunction and gut dysbiosis lead to a high risk of extraintestinal tumorigenesis.
Fri Apr 21 00:00:00 EDT 2023
Intestinal vitamin D receptor protects against extraintestinal breast cancer tumorigenesis.
Gut microbes
Zhang YG,Xia Y,Zhang J,Deb S,Garrett S,Sun J
33-9100 was used in Immunohistochemistry to provide insights into the mechanism by which intestinal VDR dysfunction and gut dysbiosis lead to a high risk of extraintestinal tumorigenesis.
Fri Apr 21 00:00:00 EDT 2023
Development of a CRISPRi Human Retinal Pigmented Epithelium Model for Functional Study of Age-Related Macular Degeneration Genes.
International journal of molecular sciences
Wang JH,Urrutia-Cabrera D,Lees JG,Mesa Mora S,Nguyen T,Hung SSC,Hewitt AW,Lim SY,Edwards TL,Wong RCB
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to highlight the potential for using CRISPRi to study age-related macular degeneration (AMD) genetics, and the CRISPRi RPE platform generated here provided a useful in vitro tool for functional studies of AMD-associated genes.
Wed Feb 08 00:00:00 EST 2023
Transcriptional Signature of Valproic Acid-Induced Neural Tube Defects in Human Spinal Cord Organoids.
International journal of stem cells
Lee JH,Shaker MR,Park SH,Sun W
33-9100 was used in Immunohistochemistry to demonstrate that hSCOs provide a valuable biological resource for dissecting the molecular pathways underlying the currently unknown human neurulation process using destructive biological analysis tools.
Thu Nov 30 00:00:00 EST 2023
Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes.
iScience
Zubiaga L,Briand O,Auger F,Touche V,Hubert T,Thevenet J,Marciniak C,Quenon A,Bonner C,Peschard S,Raverdy V,Daoudi M,Kerr-Conte J,Pasquetti G,Koepsell H,Zdzieblo D,Mühlemann M,Thorens B,Delzenne ND,Bindels LB,Deprez B,Vantyghem MC,Laferrère B,Staels B,Huglo D,Lestavel S,Pattou F
33-9100 was used in Immunohistochemistry (PFA fixed) to show that MET transiently reduced the apical density of sodium-glucose transporter 1 (SGLT1) and decreased the absorption of glucose, without changes in the mRNA levels of the transporter.
Fri Apr 21 00:00:00 EDT 2023
Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes.
iScience
Zubiaga L,Briand O,Auger F,Touche V,Hubert T,Thevenet J,Marciniak C,Quenon A,Bonner C,Peschard S,Raverdy V,Daoudi M,Kerr-Conte J,Pasquetti G,Koepsell H,Zdzieblo D,Mühlemann M,Thorens B,Delzenne ND,Bindels LB,Deprez B,Vantyghem MC,Laferrère B,Staels B,Huglo D,Lestavel S,Pattou F
33-9100 was used in Immunohistochemistry (PFA fixed) to show that MET transiently reduced the apical density of sodium-glucose transporter 1 (SGLT1) and decreased the absorption of glucose, without changes in the mRNA levels of the transporter.
Fri Apr 21 00:00:00 EDT 2023
Type I and III interferons shape the retinal cytokine network and barrier function in an in vitro model of ocular toxoplasmosis.
Frontiers in immunology
Geiller B,Greigert V,Hillenbrand CA,Gommenginger C,Beal L,Brunet J,Filisetti D,Villard O,Denis J,Pfaff AW
33-9100 was used in Immunocytochemistry-immunofluorescence to show that stimulation with type I and III interferons did not limit parasite proliferation in retinal cells we tested.
Mon May 22 00:00:00 EDT 2023
Porous honeycomb film membranes enhance endothelial barrier integrity in human vascular wall bilayer model compared to standard track-etched membranes.
Journal of biomedical materials research. Part A
Ebrahim NA,Mwizerwa ON,Ekwueme EC,Muss TE,Ersland EE,Oba T,Oku K,Nishino M,Hikimoto D,Miyoshi H,Tomotoshi K,Neville CM,Sundback CA
33-9100 was used in Immunocytochemistry to compare endothelial barrier integrity in vascular wall bilayer models with human ECs and SMCs statically cultured on opposite sides of HCFs and TEMs (5 µm pores) for up to 12 days.
Mon May 01 00:00:00 EDT 2023
Human intestinal epithelial cells can internalize luminal fungi via LC3-associated phagocytosis.
Frontiers in immunology
Cohen-Kedar S,Shaham Barda E,Rabinowitz KM,Keizer D,Abu-Taha H,Schwartz S,Kaboub K,Baram L,Sadot E,White I,Wasserberg N,Wolff-Bar M,Levy-Barda A,Dotan I
33-9100 was used in Immunocytochemistry-immunofluorescence to determine whether human intestinal epithelial cells (IECs) phagocytose β-glucan-containing fungal particles via LC3-associated phagocytosis (LAP).
Fri Mar 31 00:00:00 EDT 2023
Matriptase-dependent epidermal pre-neoplasm in zebrafish embryos caused by a combination of hypotonic stress and epithelial polarity defects.
PLoS genetics
Hatzold J,Nett V,Brantsch S,Zhang JL,Armistead J,Wessendorf H,Stephens R,Humbert PO,Iden S,Hammerschmidt M
33-9100 was used in Immunohistochemistry to identify epithelial polarity defects and systemic hypotonic stress as another mode of aberrant Matriptase activation in the embryonic zebrafish epidermis in vivo.
Tue Aug 01 00:00:00 EDT 2023
Electrical synapse structure requires distinct isoforms of a postsynaptic scaffold.
PLoS genetics
Michel JC,Grivette MMB,Harshfield AT,Huynh L,Komons AP,Loomis B,McKinnis K,Miller BT,Nguyen EQ,Huang TW,Lauf S,Michel ES,Michel ME,Kissinger JS,Marsh AJ,Crow WE,Kaye LE,Lasseigne AM,Lukowicz-Bedford RM,Farnsworth DR,Martin EA,Miller AC
33-9100 was used in Immunohistochemistry to propose that ESD molecular complexity arises both from the diversity of unique genes and from distinct isoforms encoded by single genes.
Wed Nov 01 00:00:00 EDT 2023
Dodecaploid Xenopus longipes provides insight into the emergence of size scaling relationships during development.
Current biology : CB
Miller KE,Cadart C,Heald R
33-9100 was used in Immunocytochemistry to indicate that scaling of cell size to ploidy is not due to abrupt changes in cell division timing, that different size scaling regimes occur during embryogenesis, and that the developmental program of Xenopus is remarkably consistent across a wide range of genome and egg sizes.
Mon Apr 10 00:00:00 EDT 2023
DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction.
Journal of biomedical science
Chou HC,Cheng CM,Yang CH,Lin TY,Liu YW,Tan TH,Chen YR
33-9100 was used in Western Blotting to reveal that DUSP3 is an important TJ regulatory protein and its decrease may be involved in progression of epithelial cancers.
Wed Jun 15 00:00:00 EDT 2022
Enteric nervous system modulation of luminal pH modifies the microbial environment to promote intestinal health.
PLoS pathogens
Hamilton MK,Wall ES,Robinson CD,Guillemin K,Eisen JS
33-9100 was used in Immunohistochemistry to investigated how the enteric nervous system shapes the intestinal environment in the absence of microbiota and associated inflammatory responses.
Tue Feb 01 00:00:00 EST 2022
Streptococcal autolysin promotes dysfunction of swine tracheal epithelium by interacting with vimentin.
PLoS pathogens
Meng Y,Wang Q,Ma Z,Li W,Niu K,Zhu T,Lin H,Lu C,Fan H
33-9100 was used in Western Blotting to investigate the mechanism through which Streptococcus suis serotype 2 penetrates the respiratory barrier.
Mon Aug 01 00:00:00 EDT 2022
Gli1 Regulates the Postnatal Acquisition of Peripheral Nerve Architecture.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Zotter B,Dagan O,Brady J,Baloui H,Samanta J,Salzer JL
33-9100 was used in Immunohistochemistry-immunofluorescence to delineate how peripheral nerves acquire their distinctive organization during normal development, and highlight mechanisms that may regulate their reorganization in pathologic settings, including peripheral neuropathies and nerve injury.
Wed Jan 12 00:00:00 EST 2022
KIF12 Variants and Disturbed Hepatocyte Polarity in Children with a Phenotypic Spectrum of Cholestatic Liver Disease.
The Journal of pediatrics
Stalke A,Sgodda M,Cantz T,Skawran B,Lainka E,Hartleben B,Baumann U,Pfister ED
33-9100 was used in Immunohistochemistry to report 6 cases with a likely pathogenic KIF12 variant from 4 unrelated families with different phenotypes and disease courses.
Sat Jan 01 00:00:00 EST 2022
Effects of butyrate- on ruminal Ca2+ transport: evidence for the involvement of apically expressed TRPV3 and TRPV4 channels.
Pflugers Archiv : European journal of physiology
Liebe F,Liebe H,Sponder G,Mergler S,Stumpff F
33-9100 was used in Immunohistochemistry to show that stimulation by SCFA may involve cytosolic acidification (bTRPV3) and cell swelling (bTRPV4).
Tue Mar 01 00:00:00 EST 2022
Cell-Fibronectin Interactions and Actomyosin Contractility Regulate the Segmentation Clock and Spatio-Temporal Somite Cleft Formation during Chick Embryo Somitogenesis.
Cells
Gomes de Almeida P,Rifes P,Martins-Jesus AP,Pinheiro GG,Andrade RP,Thorsteinsdóttir S
33-9100 was used in Immunohistochemistry to suggest that the fibronectin-integrin-ROCK-NM II axis regulates segmentation clock dynamics and dictates the spatio-temporal localization of somitic clefts.
Wed Jun 22 00:00:00 EDT 2022
A combination of Vitreoscilla filiformis extract and Vichy volcanic mineralizing water strengthens the skin defenses and skin barrier.
Journal of the European Academy of Dermatology and Venereology : JEADV
Gueniche A,Valois A,Kerob D,Rasmont V,Nielsen M
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to conclude that the combination of VfeV plus VVMW has properties to strengthen the skin barrier by stimulating skin differentiation and tight junctions, biochemical defenses by stimulating antimicrobial peptides, and cellular immune defenses by increasing the IL-10/IL-12 ratio and by protecting Langerhans cells challenged by ultraviolet radiation.
Sat Jan 01 00:00:00 EST 2022
Reemployment of Kupffer's vesicle cells into axial and paraxial mesoderm via transdifferentiation.
Development, growth & differentiation
Ikeda T,Inamori K,Kawanishi T,Takeda H
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to indicate that differentiated KV-epithelial cells possess unique plasticity in that they are reemployed into mesodermal lineages through transdifferentiation after they complete their initial role in KV.
Fri Apr 01 00:00:00 EDT 2022
Astrocytic VEGFA: An essential mediator in blood-brain-barrier disruption in Parkinson's disease.
Glia
Lan G,Wang P,Chan RB,Liu Z,Yu Z,Liu X,Yang Y,Zhang J
33-9100 was used in Western Blotting to illustrate that oligomeric α-syn is critically involved in PD-associated BBB disruption, in a process that is mediated by astrocyte-derived VEGFA.
Tue Feb 01 00:00:00 EST 2022
Hydrogels to Support Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells.
Brain sciences
Wei Y,Alexandre U,Ma X
33-9100 was used in Immunocytochemistry-immunofluorescence to show that fibrin is a suitable scaffold for hESC-RPE transplantation, which could be a new grafting material for tissue engineering RPE cells.
Fri Nov 25 00:00:00 EST 2022
Differential toxicity to murine small and large intestinal epithelium induced by oncology drugs.
Communications biology
Bieber JM,Sanman LE,Sun X,Hammerlindl H,Bao F,Roth MA,Koleske ML,Huang L,Aweeka F,Wu LF,Altschuler SJ
33-9100 was used in Immunocytochemistry to establish the ability to use murine small and large intestine-derived monolayers to screen drugs for toxicity.
Thu Jan 27 00:00:00 EST 2022
Nanoscale segregation of channel and barrier claudins enables paracellular ion flux.
Nature communications
Gonschior H,Schmied C,Van der Veen RE,Eichhorst J,Himmerkus N,Piontek J,Günzel D,Bleich M,Furuse M,Haucke V,Lehmann M
33-9100 was used in Immunocytochemistry to suggest that nanoscale segregation of distinct channel-forming claudins enables barrier function combined with specific paracellular ion flux across tight junctions.
Thu Aug 25 00:00:00 EDT 2022
Differential expression and localization of tight junction proteins in the goat epididymis.
Journal of animal science and technology
Kim SW,Jeong YD,Lee GY,Lee J,Lee JY,Kim CL,Ko YG,Lee SS,Kim B
33-9100 was used in Western Blot, Immunohistochemistry to suggest that the distinct expression patterns of TJ proteins are essential for regulating components of the luminal contents in the epididymal epithelium and for forming adequate luminal conditions that are necessary for the maturation, protection, transport, and storage of spermatozoa in the goat epididymis.
Sun May 01 00:00:00 EDT 2022
Differential expression and localization of tight junction proteins in the goat epididymis.
Journal of animal science and technology
Kim SW,Jeong YD,Lee GY,Lee J,Lee JY,Kim CL,Ko YG,Lee SS,Kim B
33-9100 was used in Western Blot, Immunohistochemistry to suggest that the distinct expression patterns of TJ proteins are essential for regulating components of the luminal contents in the epididymal epithelium and for forming adequate luminal conditions that are necessary for the maturation, protection, transport, and storage of spermatozoa in the goat epididymis.
Sun May 01 00:00:00 EDT 2022
The disconnect2 mutation disrupts the tjp1b gene that is required for electrical synapse formation.
microPublication biology
Michel JC,Lasseigne AM,Marsh AJ,Miller AC
33-9100 was used in Immunohistochemistry to investigate electrical synapse formation in vivo we used forward genetics to disrupt genes affecting Mauthner cell electrical synapses in larval zebrafish.
Tue Sep 12 00:00:00 EDT 2023
Activation of Wnt/β-catenin pathway mitigates blood-brain barrier dysfunction in Alzheimer's disease.
Brain : a journal of neurology
Wang Q,Huang X,Su Y,Yin G,Wang S,Yu B,Li H,Qi J,Chen H,Zeng W,Zhang K,Verkhratsky A,Niu J,Yi C
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to show dysfunctional blood-brain barrier in patients with Alzheimer's disease reflected by perivascular accumulation of blood-derived fibrinogen in the hippocampus and cortex, accompanied by decreased tight junction proteins Claudin-5 and glucose transporter Glut-1 in the brain endothelial cells.
Mon Dec 19 00:00:00 EST 2022
Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces.
Cell host & microbe
Maeda K,Zachos NC,Orzalli MH,Schmieder SS,Chang D,Bugda Gwilt K,Doucet M,Baetz NW,Lee S,Crawford SE,Estes MK,Kagan JC,Turner JR,Lencer WI
33-9100 was used in Immunocytochemistry-immunofluorescence to find that in response to the entry of certain viruses and bacterial toxins into the epithelial cells via the apical membrane, PARD6B and aPKC, two components of the PARD6B-aPKC-Cdc42 apical polarity complex, undergo rapid proteasome-dependent degradation.
Wed Feb 09 00:00:00 EST 2022
The ACE2 Receptor for Coronavirus Entry Is Localized at Apical Cell-Cell Junctions of Epithelial Cells.
Cells
Rouaud F,Méan I,Citi S
33-9100 was used in Western Blotting to identify ACE2, ADAM17 and CD9 as new epithelial junctional transmembrane proteins and suggest that the cytokine-enhanced endocytic internalization of junction-associated protein complexes comprising ACE2 may promote coronavirus entry.
Fri Feb 11 00:00:00 EST 2022
Canine Epidermal Keratinocytes (CPEK) Grown in Monolayer Are Not Representative of Normal Canine Keratinocytes for Permeability Studies: Pilot Studies.
Veterinary sciences
Marsella R,Wilkes R,Ahrens K
33-9100 was used in Immunocytochemistry-immunofluorescence to compare transepithelial electric resistance (TEER) and tight junction (TJ) expression in canine progenitor epidermal keratinocytes (CPEK) and normal keratinocytes (NK) harvested from biopsies of normal dogs.
Tue Jan 11 00:00:00 EST 2022
Schizophrenia-derived hiPSC brain microvascular endothelial-like cells show impairments in angiogenesis and blood-brain barrier function.
Molecular psychiatry
Casas BS,Vitória G,Prieto CP,Casas M,Chacón C,Uhrig M,Ezquer F,Ezquer M,Rehen SK,Palma V
33-9100 was used in Immunocytochemistry-immunofluorescence to describe an intrinsic failure of SZP BEC for proper barrier function.
Thu Sep 01 00:00:00 EDT 2022
Addition of Chk1 inhibitor and BMP4 cooperatively promotes retinal tissue formation in self-organizing human pluripotent stem cell differentiation culture.
Regenerative therapy
Yamasaki S,Kuwahara A,Kishino A,Kimura T,Takahashi M,Mandai M
33-9100 was used in Immunohistochemistry to find that combined use of rhBMP4 and a Chk1 inhibitor cooperatively promoted retinal differentiation from hPSCs.
Tue Mar 01 00:00:00 EST 2022
CYP1B1 Augments the Mesenchymal, Claudin-Low, and Chemoresistant Phenotypes of Triple-Negative Breast Cancer Cells.
International journal of molecular sciences
Hollis PR,Mobley RJ,Bhuju J,Abell AN,Sutter CH,Sutter TR
33-9100 was used in Immunocytochemistry-immunofluorescence to report on in vitro studies in triple-negative breast cancer cell lines, where knockdown (KD) of CYP1B1 was used to determine the influence of its expression on invasive cell phenotypes.
Fri Aug 26 00:00:00 EDT 2022
Short-term and bystander effects of radiation on murine submandibular glands.
Disease models & mechanisms
Uchida H,Ingalls MH,Maruyama EO,Johnston CJ,Hernady E,Faustoferri RC,Ovitt CE
33-9100 was used in Immunohistochemistry (Paraffin) to investigate the mechanisms of cellular damage induced by radiation treatment.
Tue Nov 01 00:00:00 EDT 2022
Differences in Behavior between Normal and Atopic Keratinocytes in Culture: Pilot Studies.
Veterinary sciences
Marsella R,Ahrens K,Wilkes R
33-9100 was used in Immunocytochemistry-immunofluorescence to investigate TEER in normal and atopic keratinocytes.
Thu Jun 30 00:00:00 EDT 2022
A Model of Human Small Airway on a Chip for Studies of Subacute Effects of Inhalation Toxicants.
Toxicological sciences : an official journal of the Society of Toxicology
Sakolish C,Georgescu A,Huh DD,Rusyn I
33-9100 was used in Immunocytochemistry to demonstrate a device that can be easily manufactured while allowing for the production of a differentiated lung tissue and generate quantitative, high-content data that were indicative of aberrant changes in biochemical (lactate dehydrogenase), barrier (dextran permeability), functional (ciliary beating), and molecular (imaging for various markers) phenotypes of the small airway epithelium due to inhalational exposures.
Thu May 26 00:00:00 EDT 2022
Development of an electrospun poly(ε-caprolactone)/collagen-based human amniotic membrane powder scaffold for culturing retinal pigment epithelial cells.
Scientific reports
Majidnia E,Ahmadian M,Salehi H,Amirpour N
33-9100 was used in Immunocytochemistry-immunofluorescence to indicate that PCL-30HAMP fibrous scaffold has a great potential to be used in retinal tissue engineering applications.
Tue Apr 19 00:00:00 EDT 2022
DAPLE orchestrates apical actomyosin assembly from junctional polarity complexes.
The Journal of cell biology
Marivin A,Ho RX,Garcia-Marcos M
33-9100 was used in Immunohistochemistry to establish DAPLE as a direct molecular link between junctional polarity complexes and the formation of apical cytoskeletal assemblies that support epithelial cell shape.
Mon May 02 00:00:00 EDT 2022
Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression.
American journal of physiology. Cell physiology
Koumangoye R,Penny P,Delpire E
33-9100 was used in Immunocytochemistry to investigate whether the loss of Na+-K+-2Cl- cotransporter function affects paracellular ion transport and epithelial barrier function.
Sat Oct 01 00:00:00 EDT 2022
FYN regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization via its effect on Arp3 in the mouse testis.
Frontiers in immunology
Yang Y,Yao M,Zeng J,Zheng D,Li Q,Ni Y,Xiao X
33-9100 was used in Immunohistochemistry-immunofluorescence to show that it is also possible for viruses to break through the BTB and enter the immunoprivileged testicular microenvironment via this mechanism.
Mon Aug 29 00:00:00 EDT 2022
Force-dependent remodeling of cytoplasmic ZO-1 condensates contributes to cell-cell adhesion through enhancing tight junctions.
iScience
Kinoshita N,Yamamoto TS,Yasue N,Takagi C,Fujimori T,Ueno N
33-9100 was used in Immunocytochemistry-immunofluorescence to propose that the force-dependent regulation of ZO-1 condensation contributes to the establishment of robust cell-cell adhesion during early development.
Fri Feb 18 00:00:00 EST 2022
Two-stage degradation and novel functional endothelium characteristics of a 3-D printed bioresorbable scaffold.
Bioactive materials
Yin T,Du R,Wang Y,Huang J,Ge S,Huang Y,Tan Y,Liu Q,Chen Z,Feng H,Du J,Wang Y,Wang G
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to investigate the inflexion point of degradation, the response of blood vessels, and the pathophysiological process of vascular, as results of such studies will be of great value for the design of next generation of bioresorbable scaffolds.
Fri Apr 01 00:00:00 EDT 2022
ZO-1 Guides Tight Junction Assembly and Epithelial Morphogenesis via Cytoskeletal Tension-Dependent and -Independent Functions.
Cells
Haas AJ,Zihni C,Krug SM,Maraspini R,Otani T,Furuse M,Honigmann A,Balda MS,Matter K
33-9100 was used in Western Blotting to reveal that reciprocal regulation between ZO-1 and cell mechanics controls tight junction assembly and epithelial morphogenesis, and that, in a second, tension-independent step, ZO-1 is required to assemble morphologically and structurally fully assembled and functionally normal tight junctions.
Fri Nov 25 00:00:00 EST 2022
Rotavirus activates MLKL-mediated host cellular necroptosis concomitantly with apoptosis to facilitate dissemination of viral progeny.
Molecular microbiology
Mukhopadhyay U,Patra U,Chandra P,Saha P,Gope A,Dutta M,Chawla-Sarkar M
33-9100 was used in Immunocytochemistry-immunofluorescence to show that MLKL is one of the dominant mediators of cell death following RV infection.
Fri Apr 01 00:00:00 EDT 2022
Novel insight into the role of clusterin on intraocular pressure regulation by modifying actin polymerization and extracellular matrix remodeling in the trabecular meshwork.
Journal of cellular physiology
Soundararajan A,Wang T,Ghag SA,Kang MH,Pattabiraman PP
33-9100 was used in Western Blotting to provide comprehensive mechanistic evidence for the role of clusterin in the modulation of intraocular pressure by regulating the trabecular meshwork, actin cytoskeleton, and the extracellular matrix.
Fri Jul 01 00:00:00 EDT 2022
Biofabrication of synthetic human liver tissue with advanced programmable functions.
iScience
Florentino RM,Morita K,Haep N,Motomura T,Diaz-Aragon R,Faccioli LAP,Collin de l'Hortet A,Cetin Z,Frau C,Vernetti L,Amler AK,Thomas A,Lam T,Kloke L,Takeishi K,Taylor DL,Fox IJ,Soto-Gutierrez A
33-9100 was used in Immunocytochemistry-immunofluorescence to create synthetic human liver tissue with programmable genetically enhanced functions by generating human induced pluripotent stem cells (iPSCs) and using CRISPR-Cas9 synergistic activation mediator to enhance the expression of CYP3A4 and UGT1A1 genes.
Thu Dec 22 00:00:00 EST 2022
Routine culture and study of adult human brain cells from neurosurgical specimens.
Nature protocols
Park TI,Smyth LCD,Aalderink M,Woolf ZR,Rustenhoven J,Lee K,Jansson D,Smith A,Feng S,Correia J,Heppner P,Schweder P,Mee E,Dragunow M
33-9100 was used in Immunocytochemistry to enable the investigation of human brain cells and facilitate translation of neuroscience research to the clinic.
Tue Feb 01 00:00:00 EST 2022
The natural antisense transcript HAS2-AS1 regulates breast cancer cells aggressiveness independently from hyaluronan metabolism.
Matrix biology : journal of the International Society for Matrix Biology
Parnigoni A,Caon I,Teo WX,Hua SH,Moretto P,Bartolini B,Viola M,Karousou E,Yip GW,Götte M,Heldin P,Passi A,Vigetti D
33-9100 was used in Immunocytochemistry to reveal that the overexpression of either the full-length HAS2-AS1 or its exon 2 long or short isoforms alone, strongly reduced cell viability, migration, and invasion, whereas HAS2-AS1 silencing increased cell aggressiveness.
Sun May 01 00:00:00 EDT 2022
Heterogeneity of Potassium Channels in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium.
Stem cells translational medicine
Korkka I,Skottman H,Nymark S
33-9100 was used in Immunocytochemistry to suggest that in the hESC-RPE, the characteristics of the delayed rectifier and M-currents resemble native adult RPE, while A-type and Kir currents resemble native hfRPE or cultured primary RPE.
Wed Jul 20 00:00:00 EDT 2022
Lactic acid from vaginal microbiota enhances cervicovaginal epithelial barrier integrity by promoting tight junction protein expression.
Microbiome
Delgado-Diaz DJ,Jesaveluk B,Hayward JA,Tyssen D,Alisoltani A,Potgieter M,Bell L,Ross E,Iranzadeh A,Allali I,Dabee S,Barnabas S,Gamieldien H,Blackburn JM,Mulder N,Smith SB,Edwards VL,Burgener AD,Bekker LG,Ravel J,Passmore JS,Masson L,Hearps AC,Tachedjian G
33-9100 was used in Western Blotting to reveal a novel ability of vaginal lactic acid to enhance genital epithelial barrier integrity that may help prevent invasion by sexually transmitted pathogens.
Wed Aug 31 00:00:00 EDT 2022
Organotypic sinonasal airway culture systems are predictive of the mucociliary phenotype produced by bronchial airway epithelial cells.
Scientific reports
Delhove J,Alawami M,Macowan M,Lester SE,Nguyen PT,Jersmann HPA,Reynolds PN,Roscioli E
33-9100 was used in Western Blotting to apply a tissue engineering approach to generate organotypic sinonasal AEC (nAEC) epithelia to determine whether they are predictive of bronchial AEC (bAEC) models.
Thu Nov 10 00:00:00 EST 2022
Novel Compound Heterozygous Variations in MPDZ Gene Caused Isolated Bilateral Macular Coloboma in a Chinese Family.
Cells
Zhang S,Zhang F,Wang J,Yang S,Ren Y,Rui X,Xia X,Sheng X
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to study how MPDZ plays an essential role in the occurrence and maintenance of the macula, and the novel compound heterozygous variations were responsible for an autosomal recessive macular deficiency in this Chinese family.
Mon Nov 14 00:00:00 EST 2022
Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia.
Nature biomedical engineering
Cruz NM,Reddy R,McFaline-Figueroa JL,Tran C,Fu H,Freedman BS
33-9100 was used in Immunocytochemistry to show that human cilia mediate a critical switch in hedgehog signalling during organoid differentiation, and that they constitutively release extracellular vesicles containing signalling molecules associated with ciliopathy phenotypes.
Fri Apr 01 00:00:00 EDT 2022
Transport of cationic liposomes in a human blood brain barrier model: Role of the stereochemistry of the gemini amphiphile on liposome biological features.
Journal of colloid and interface science
Simonis B,Vignone D,Gonzalez Paz O,Donati E,Falchetti ML,Bombelli C,Cellucci A,Auciello G,Fini I,Galantini L,Syeda RZ,Mazzonna M,Mongiardi MP,Buonocore F,Ceccacci F,Di Marco A,Mancini G
33-9100 was used in Immunocytochemistry to create liposomes containing cationic diastereomeric gemini amphiphiles, which were found to enhance their permeability across the Blood-Brain Barrier (BBB) through energy-dependent transport and endocytosis mechanisms in in vitro BBB models, indicating their potential significance in advancing brain delivery strategies for central nervous system diseases.
Thu Dec 01 00:00:00 EST 2022
Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function.
Nature neuroscience
Liu CC,Zhao J,Fu Y,Inoue Y,Ren Y,Chen Y,Doss SV,Shue F,Jeevaratnam S,Bastea L,Wang N,Martens YA,Qiao W,Wang M,Zhao N,Jia L,Yamazaki Y,Yamazaki A,Rosenberg CL,Wang Z,Kong D,Li Z,Kuchenbecker LA,Trottier ZA,Felton L,Rogers J,Quicksall ZS,Linares C,Knight J,Chen Y,Kurti A,Kanekiyo T,Fryer JD,Asmann YW,Storz P,Wang X,Peng J,Zhang B,Kim BYS,Bu G
33-9100 was used in Immunohistochemistry to demonstrate pathogenic effects of peripheral apoE4, providing a strong rationale for targeting peripheral apoE to treat Alzheimer's disease.
Mon Aug 01 00:00:00 EDT 2022
A medium composition containing normal resting glucose that supports differentiation of primary human airway cells.
Scientific reports
Morgan R,Manfredi C,Easley KF,Watkins LD,Hunt WR,Goudy SL,Sorscher EJ,Koval M,Molina SA
33-9100 was used in Immunocytochemistry to demonstrate that normal glucose containing medium supports differentiation of primary nasal and lung epithelial cells at ALI, is well suited for metabolic studies, and avoids pitfalls associated with exposure to high glucose.
Thu Jan 27 00:00:00 EST 2022
Engineering rotating apical-out airway organoid for assessing respiratory cilia motility.
iScience
Wijesekara P,Yadav P,Perkins LA,Stolz DB,Franks JM,Watkins SC,Reinoso Jacome E,Brody SL,Horani A,Xu J,Barati Farimani A,Ren X
33-9100 was used in Immunohistochemistry to describe a robust approach for reproducible engineering of apical-out airway organoid (AOAO) from a defined number of cells.
Fri Aug 19 00:00:00 EDT 2022
Inhibition of retinoid X receptor improved the morphology, localization of desmosomal proteins and paracellular permeability in three-dimensional cultures of mouse keratinocytes.
Microscopy (Oxford, England)
Ishikawa S,Nikaido M,Otani T,Ogata K,Iida H,Inai Y,Tamaoki S,Inai T
33-9100 was used in Immunocytochemistry-immunofluorescence to find that treatment of K38 3D culture with HX531 improves cellular morphology by reducing intercellular spaces, increasing desmosomal and tight junction proteins as well as transepithelial electrical resistance.
Mon Jun 06 00:00:00 EDT 2022
Curcumin Mitigates TNFα-Induced Caco-2 Cell Monolayer Permeabilization Through Modulation of NF-κB, ERK1/2, and JNK Pathways.
Molecular nutrition & food research
Iglesias DE,Cremonini E,Oteiza PI,Fraga CG
33-9100 was used in Western Blotting to study the capacity of curcumin to inhibit tumor necrosis alpha (TNFα)-induced inflammation, oxidative stress, and loss of intestinal barrier integrity, characterizing the underlying mechanisms.Caco-2 cell monolayers are incubated with TNFα (10 ng mL-1 ), in the absence or presence of curcumin.
Tue Nov 01 00:00:00 EDT 2022
Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration.
Nature communications
Senabouth A,Daniszewski M,Lidgerwood GE,Liang HH,Hernández D,Mirzaei M,Keenan SN,Zhang R,Han X,Neavin D,Rooney L,Lopez Sanchez MIG,Gulluyan L,Paulo JA,Clarke L,Kearns LS,Gnanasambandapillai V,Chan CL,Nguyen U,Steinmann AM,McCloy RA,Farbehi N,Gupta VK,Mackey DA,Bylsma G,Verma N,MacGregor S,Watt MJ,Guymer RH,Powell JE,Hewitt AW,Pébay A
33-9100 was used in Immunocytochemistry to uncover important differences in retinal pigment epithelium homeostasis associated with geographic atrophy.
Tue Jul 26 00:00:00 EDT 2022
Extracellular Alterations in pH and K+ Modify the Murine Brain Endothelial Cell Total and Phospho-Proteome.
Pharmaceutics
Wahl JR,Vivek A,Palomino SM,Almuslim M,Cottier KE,Langlais PR,Streicher JM,Vanderah TW,Liktor-Busa E,Largent-Milnes TM
33-9100 was used in Immunocytochemistry-immunoflourescence to demonstrate relocalization and functional alteration to proteins associated with the actin cytoskeleton and endothelial tight junctions.
Fri Jul 15 00:00:00 EDT 2022
Canid herpesvirus 1 Preferentially Infects Polarized Madin-Darby Canine Kidney Cells from the Basolateral Surface.
Viruses
Eisa M,Micky S,Pearson A
33-9100 was used in Immunocytochemistry to elucidate that CHV-1 infects polarized MDCK cells from the basolateral side in a preferential manner, to give overall higher viral tiers.
Tue Jun 14 00:00:00 EDT 2022
Immunosuppressants Tacrolimus and Sirolimus revert the cardiac antifibrotic properties of p38-MAPK inhibition in 3D-multicellular human iPSC-heart organoids.
Frontiers in cell and developmental biology
Tian Y,Tsujisaka Y,Li VY,Tani K,Lucena-Cacace A,Yoshida Y
33-9100 was used in Immunocytochemistry-immunofluorescence to find that the inhibition of the p38-MAPK pathway significantly reduces COL1A1 depositions.
Tue Nov 29 00:00:00 EST 2022
Peripartal treatment with low-dose sertraline accelerates mammary gland involution and has minimal effects on maternal and offspring bone.
Physiological reports
Sheftel CM,Sartori LC,Hunt ER,Manuel RSJ,Bell AM,Domingues RR,Wake LA,Scharpf BR,Vezina CM,Charles JF,Hernandez LL
33-9100 was used in Immunohistochemistry to indicate that peripartum sertraline treatment may be a safer SSRI for maternal and offspring bone rather than fluoxetine.
Tue Mar 01 00:00:00 EST 2022
A chemically-defined plastic scaffold for the xeno-free production of human pluripotent stem cells.
Scientific reports
Shimizu E,Iguchi H,Le MNT,Nakamura Y,Kobayashi D,Arai Y,Takakura K,Benno S,Yoshida N,Tsukahara M,Haneda S,Hasegawa K
33-9100 was used in Immunocytochemistry to develop a chemically synthetic culture substrate for human pluripotent stem cell attachment and maintenance.
Tue Feb 15 00:00:00 EST 2022
Stage-Specific Generation of Human Pluripotent Stem Cell Derived Lung Models to Measure CFTR Function.
Current protocols
Ngan SY,Quach HT,Laselva O,Huang EN,Mangos M,Xia S,Bear CE,Wong AP
33-9100 was used in Immunocytochemistry-immunofluorescence to optimize previously published protocols to efficiently generate three developmental stages of the lung model (fetal lung epithelial progenitors, fLEP; immature airway epithelial spheroid, AES; air-liquid interface culture, ALI), and demonstrate its potential for cystic fibrosis (CF) drug discovery platforms.
Sat Jan 01 00:00:00 EST 2022
Oxidative stress differentially impacts apical and basolateral secretion of angiogenic factors from human iPSC-derived retinal pigment epithelium cells.
Scientific reports
Chen L,Perera ND,Karoukis AJ,Feathers KL,Ali RR,Thompson DA,Fahim AT
33-9100 was used in Immunocytochemistry to lay a foundation for investigations of dysfunctional RPE polarized protein secretion in AMD and other chorioretinal degenerative disorders.
Tue Jul 26 00:00:00 EDT 2022
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication.
Nature cell biology
Tanaka J,Senpuku H,Ogawa M,Yasuhara R,Ohnuma S,Takamatsu K,Watanabe T,Mabuchi Y,Nakamura S,Ishida S,Sadaoka T,Takaki T,Shirota T,Shimane T,Inoue T,Sakai T,Mori M,Tsuji T,Saito I,Mishima K
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to show that human induced salivary glands (hiSGs) generated from human induced pluripotent stem cells can be infected with SARS-CoV-2.
Tue Nov 01 00:00:00 EDT 2022
Evaluation of a Rapid and Simple Method for Assessing Retinal Vessel Structures in Adult Zebrafish.
International journal of molecular sciences
Lee YR,Son M,Kim YS,Kim JS,Kim CH,Jung SH
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to provide a rapid and convenient method for the study of retinal vasculature disease in the zebrafish animal model.
Thu Dec 01 00:00:00 EST 2022
Simple and efficient protocol to isolate and culture brain microvascular endothelial cells from newborn mice.
Frontiers in cellular neuroscience
Nicolicht-Amorim P,Delgado-Garcia LM,Nakamura TKE,Courbassier NR,Mosini AC,Porcionatto MA
Simple and efficient protocol to isolate and culture brain microvascular endothelial cells from newborn mice
Wed Nov 02 00:00:00 EDT 2022
Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.
Nature
Pastushenko I,Mauri F,Song Y,de Cock F,Meeusen B,Swedlund B,Impens F,Van Haver D,Opitz M,Thery M,Bareche Y,Lapouge G,Vermeersch M,Van Eycke YR,Balsat C,Decaestecker C,Sokolow Y,Hassid S,Perez-Bustillo A,Agreda-Moreno B,Rios-Buceta L,Jaen P,Redondo P,Sieira-Gil R,Millan-Cayetano JF,Sanmatrtin O,D'Haene N,Moers V,Rozzi M,Blondeau J,Lemaire S,Scozzaro S,Janssens V,De Troya M,Dubois C,Pérez-Morga D,Salmon I,Sotiriou C,Helmbacher F,Blanpain C
33-9100 was used in Immunohistochemistry to demonstrate that deletion of Fat1, which encodes a protocadherin, promotes malignant progression by controlling cell polarity and adhesion between tumour cells, and between tumour cells and the extracellular matrix.
Fri Jan 01 00:00:00 EST 2021
A cellular and spatial map of the choroid plexus across brain ventricles and ages.
Cell
Dani N,Herbst RH,McCabe C,Green GS,Kaiser K,Head JP,Cui J,Shipley FB,Jang A,Dionne D,Nguyen L,Rodman C,Riesenfeld SJ,Prochazka J,Prochazkova M,Sedlacek R,Zhang F,Bryja V,Rozenblatt-Rosen O,Habib N,Regev A,Lehtinen MK
33-9100 was used in Immunohistochemistry to reveal cellular diversity, architecture and signaling across ventricles during development, maturation, and aging of the ChP-brain barrier.
Thu May 27 00:00:00 EDT 2021
SARS-CoV-2 crosses the blood-brain barrier accompanied with basement membrane disruption without tight junctions alteration.
Signal transduction and targeted therapy
Zhang L,Zhou L,Bao L,Liu J,Zhu H,Lv Q,Liu R,Chen W,Tong W,Wei Q,Xu Y,Deng W,Gao H,Xue J,Song Z,Yu P,Han Y,Zhang Y,Sun X,Yu X,Qin C
33-9100 was used in Immunohistochemistry to elucidate whether and how SARS-CoV-2 crosses the blood-brain barrier.
Mon Sep 06 00:00:00 EDT 2021
Cell fate coordinates mechano-osmotic forces in intestinal crypt formation.
Nature cell biology
Yang Q,Xue SL,Chan CJ,Rempfler M,Vischi D,Maurer-Gutierrez F,Hiiragi T,Hannezo E,Liberali P
33-9100 was used in Immunohistochemistry to demonstrate that crypt formation coincides with a stark reduction in lumen volume.
Thu Jul 01 00:00:00 EDT 2021
Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells.
Cell stem cell
Breunig M,Merkle J,Wagner M,Melzer MK,Barth TFE,Engleitner T,Krumm J,Wiedenmann S,Cohrs CM,Perkhofer L,Jain G,Krüger J,Hermann PC,Schmid M,Madácsy T,Varga Á,Griger J,Azoitei N,Müller M,Wessely O,Robey PG,Heller S,Dantes Z,Reichert M,Günes C,Bolenz C,Kuhn F,Maléth J,Speier S,Liebau S,Sipos B,Kuster B,Seufferlein T,Rad R,Meier M,Hohwieler M,Kleger A
33-9100 was used in Immunocytochemistry-immunoflourescence to show that PDLOs enable in vitro and in vivo studies of pancreatic plasticity, dysplasia, and cancer formation from a genetically defined background.
Thu Jun 03 00:00:00 EDT 2021
3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration.
Cell stem cell
Manian KV,Galloway CA,Dalvi S,Emanuel AA,Mereness JA,Black W,Winschel L,Soto C,Li Y,Song Y,DeMaria W,Kumar A,Slukvin I,Schwartz MP,Murphy WL,Anand-Apte B,Chung M,Benoit DSW,Singh R
33-9100 was used in Immunohistochemistry to represent that the human 3D model described here provides a platform for investigating RPE-CC biology, AMD/MD pathophysiology, and testing new therapeutic interventions.
Thu May 06 00:00:00 EDT 2021
Endoplasmic reticulum-associated degradation is required for nephrin maturation and kidney glomerular filtration function.
The Journal of clinical investigation
Yoshida S,Wei X,Zhang G,O'Connor CL,Torres M,Zhou Z,Lin L,Menon R,Xu X,Zheng W,Xiong Y,Otto E,Tang CA,Hua R,Verma R,Mori H,Zhang Y,Hu CA,Liu M,Garg P,Hodgin JB,Sun S,Bitzer M,Qi L
33-9100 was used in Immunohistochemistry to uncover a critical role of SEL1L-HRD1 ERAD in glomerular filtration barrier function and provides insights into the pathogenesis associated with autosomal-recessive disease mutants.
Thu Apr 01 00:00:00 EDT 2021
A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy.
EMBO molecular medicine
Chidiac R,Abedin M,Macleod G,Yang A,Thibeault PE,Blazer LL,Adams JJ,Zhang L,Roehrich H,Jo HN,Seshagiri S,Sidhu SS,Junge HJ,Angers S
33-9100 was used in Western Blot to develop F4L5.13, a tetravalent antibody designed to induce FZD4 and LRP5 proximity in such a way as to trigger βcatenin signaling.
Wed Jul 07 00:00:00 EDT 2021
A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy.
EMBO molecular medicine
Chidiac R,Abedin M,Macleod G,Yang A,Thibeault PE,Blazer LL,Adams JJ,Zhang L,Roehrich H,Jo HN,Seshagiri S,Sidhu SS,Junge HJ,Angers S
33-9100 was used in Western Blot to develop F4L5.13, a tetravalent antibody designed to induce FZD4 and LRP5 proximity in such a way as to trigger βcatenin signaling.
Wed Jul 07 00:00:00 EDT 2021
Diet Alters Entero-Mammary Signaling to Regulate the Breast Microbiome and Tumorigenesis.
Cancer research
Soto-Pantoja DR,Gaber M,Arnone AA,Bronson SM,Cruz-Diaz N,Wilson AS,Clear KYJ,Ramirez MU,Kucera GL,Levine EA,Lelièvre SA,Chaboub L,Chiba A,Yadav H,Vidi PA,Cook KL
33-9100 was used in Immunocytochemistry-immunoflourescence to demonstrate that diet shifts the microbiome in the gut and the breast tumor microenvironment to affect tumorigenesis, and oral dietary interventions can modulate the tumor microbiota in patients with breast cancer.
Thu Jul 15 00:00:00 EDT 2021
Ciliopathy genes are required for apical secretion of Cochlin, an otolith crystallization factor.
Proceedings of the National Academy of Sciences of the United States of America
Leventea E,Zhu Z,Fang X,Nikolaeva Y,Markham E,Hirst RA,van Eeden FJM,Malicki JJ
33-9100 was used in Immunohistochemistry to reveals a class of ciliary proteins that are important for the polarity of secretion and delineate a secretory pathway that regulates biomineralization.
Tue Jul 13 00:00:00 EDT 2021
Enhanced structure and function of human pluripotent stem cell-derived beta-cells cultured on extracellular matrix.
Stem cells translational medicine
Singh R,Cottle L,Loudovaris T,Xiao D,Yang P,Thomas HE,Kebede MA,Thorn P
33-9100 was used in Immunocytochemistry to identify the role of basement membrane proteins on the structure and function of human embryonic stem cell and induced pluripotent stem cell-derived beta cells.
Mon Mar 01 00:00:00 EST 2021
Tight junctions in the blood-brain barrier promote edema formation and infarct size in stroke - Ambivalent effects of sealing proteins.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Winkler L,Blasig R,Breitkreuz-Korff O,Berndt P,Dithmer S,Helms HC,Puchkov D,Devraj K,Kaya M,Qin Z,Liebner S,Wolburg H,Andjelkovic AV,Rex A,Blasig IE,Haseloff RF
33-9100 was used in Immunocytochemistry to assess the effects of claudin 3 deficiency and stress factors on the BBB and its tight junctions.
Fri Jan 01 00:00:00 EST 2021
CAMSAP3 is required for mTORC1-dependent ependymal cell growth and lateral ventricle shaping in mouse brains.
Development (Cambridge, England)
Kimura T,Saito H,Kawasaki M,Takeichi M
33-9100 was used in Immunohistochemistry to suggest that CAMSAP3 supports mTORC1 signaling required for ependymal cell growth via MT network regulation, and, in turn, shaping of the lateral ventricles.
Fri Feb 05 00:00:00 EST 2021
Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds.
Development (Cambridge, England)
Kowalczyk I,Lee C,Schuster E,Hoeren J,Trivigno V,Riedel L,Görne J,Wallingford JB,Hammes A,Feistel K
33-9100 was used in Immunohistochemistry to suggest that, during neurulation, motifs within the intracellular domain of Lrp2 function as a hub that orchestrates endocytic membrane removal for efficient apical constriction, as well as PCP component trafficking in a temporospatial manner.
Tue Jan 26 00:00:00 EST 2021
Glial-Specific Deletion of Med12 Results in Rapid Hearing Loss via Degradation of the Stria Vascularis.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Huang TW,Iyer AA,Manalo JM,Woo J,Bosquez Huerta NA,McGovern MM,Schrewe H,Pereira FA,Groves AK,Ohlemiller KK,Deneen B
33-9100 was used in Immunohistochemistry (Frozen) to study the effects of temporal conditional deletion of Med12 in astrocytes in the adult CNS.
Wed Aug 25 00:00:00 EDT 2021
A comparative analysis of SARS-CoV-2 antivirals characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19.
Journal of virology
de Vries M,Mohamed AS,Prescott RA,Valero-Jimenez AM,Desvignes L,O'Connor R,Steppan C,Devlin JC,Ivanova E,Herrera A,Schinlever A,Loose P,Ruggles K,Koralov SB,Anderson AS,Binder J,Dittmann M
33-9100 was used in Immunohistochemistry to provide in vitro evidence for the potential of PF-00835231 as an effective SARS-CoV-2 antiviral and addresses concerns that emerged based on prior studies in non-human in vitro models.
Wed Mar 10 00:00:00 EST 2021
MAGI-1 PDZ2 Domain Blockade Averts Adenovirus Infection via Enhanced Proteolysis of the Apical Coxsackievirus and Adenovirus Receptor.
Journal of virology
Alghamri MS,Sharma P,Williamson TL,Readler JM,Yan R,Rider SD,Hostetler HA,Cool DR,Kolawole AO,Excoffon KJDA
33-9100 was used in Western Blot to show that the interactions between the MAGI-1 PDZ2 domain and CAREx8 would decrease the apical CAREx8 expression level and prevent AdV infection.
Thu Jun 10 00:00:00 EDT 2021
Mucus Hypersecretion and Ciliary Impairment in Conducting Airway Contribute to Alveolar Mucus Plugging in Idiopathic Pulmonary Fibrosis.
Frontiers in cell and developmental biology
Peng Y,Wang ZN,Xu AR,Fang ZF,Chen SY,Hou XT,Zhou ZQ,Lin HM,Xie JX,Tang XX,Wang DY,Zhong NS
33-9100 was used in Immunohistochemistry to investigate whether the muco-ciliary clearance abnormalities in conducting airway are involved in idiopathic pulmonary fibrosis pathogenesis.
Sat Feb 19 00:00:00 EST 2022
In well-differentiated primary human bronchial epithelial cells, TGF-β1 and TGF-β2 induce expression of furin.
American journal of physiology. Lung cellular and molecular physiology
O'Sullivan MJ,Mitchel JA,Mwase C,McGill M,Kanki P,Park JA
33-9100 was used in Immunocytochemistry to look into whether well-differentiated HBE cells maintained in air-liquid interface is a reliable in vitro system for investigating cellular mechanisms of SARS-CoV-2 infection.
Mon Feb 01 00:00:00 EST 2021
Transmembrane and Immunoglobulin Domain Containing 1, a Putative Tumor Suppressor, Induces G2/M Cell Cycle Checkpoint Arrest in Colon Cancer Cells.
The American journal of pathology
De La Cena KOC,Ho RX,Amraei R,Woolf N,Tashjian JY,Zhao Q,Richards S,Walker J,Huang J,Chitalia VC,Rahimi N
33-9100 was used in Immunohistochemistry to investigate the full molecular mechanisms deriving colorectal cancer tumorigenesis.
Fri Jan 01 00:00:00 EST 2021
Transmembrane and Immunoglobulin Domain Containing 1, a Putative Tumor Suppressor, Induces G2/M Cell Cycle Checkpoint Arrest in Colon Cancer Cells.
The American journal of pathology
De La Cena KOC,Ho RX,Amraei R,Woolf N,Tashjian JY,Zhao Q,Richards S,Walker J,Huang J,Chitalia VC,Rahimi N
33-9100 was used in Immunohistochemistry to investigate the full molecular mechanisms deriving colorectal cancer tumorigenesis.
Fri Jan 01 00:00:00 EST 2021
RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers.
Frontiers in oncology
Abraham HG,Ulintz PJ,Goo L,Yates JA,Little AC,Bao L,Wu Z,Merajver SD
33-9100 was used in Immunohistochemistry, Western Blot to study how RhoA- and RhoC-GTPase influence the cell-cell junctions in aggressive breast cancers.
Tue Nov 07 00:00:00 EST 2023
RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers.
Frontiers in oncology
Abraham HG,Ulintz PJ,Goo L,Yates JA,Little AC,Bao L,Wu Z,Merajver SD
33-9100 was used in Immunohistochemistry, Western Blot to study how RhoA- and RhoC-GTPase influence the cell-cell junctions in aggressive breast cancers.
Tue Nov 07 00:00:00 EST 2023
A liquid culture cancer spheroid model reveals low PI3K/Akt pathway activity and low adhesiveness to the extracellular matrix.
The FEBS journal
Abe-Fukasawa N,Watanabe R,Gen Y,Nishino T,Itasaki N
33-9100 was used in Immunocytochemistry to examine such liquid culture cancer spheroids for the acquisition of apical-basal polarity, sensitivity to an Akt inhibitor (anticancer drug MK-2206) and interaction with extracellular matrix.
Fri Oct 01 00:00:00 EDT 2021
Inducible Slc4a11 Knockout Triggers Corneal Edema Through Perturbation of Corneal Endothelial Pump.
Investigative ophthalmology & visual science
Ogando DG,Shyam R,Kim ET,Wang YC,Liu CY,Bonanno JA
33-9100 was used in Immunohistochemistry to examine early events following loss of Slc4a11 activity.
Tue Jun 01 00:00:00 EDT 2021
Variants of human CLDN9 cause mild to profound hearing loss.
Human mutation
Ramzan M,Philippe C,Belyantseva IA,Nakano Y,Fenollar-Ferrer C,Tona R,Yousaf R,Basheer R,Imtiaz A,Faridi R,Munir Z,Idrees H,Salman M,Nambot S,Vitobello A,Kartti S,Zarrik O,Witmer PD,Sobreria N,Ibrahimi A,Banfi B,Moutton S,Friedman TB,Naz S
33-9100 was used in Immunohistochemistry to expand the genotype-phenotype spectrum of CLDN9-associated deafness and describe two different homozygous variants in individuals from two unrelated families affected with prelingual or adolescent-onset hearing loss.
Fri Oct 01 00:00:00 EDT 2021
Syncytialization and prolonged exposure to palmitate impacts BeWo respiration.
Reproduction (Cambridge, England)
Easton ZJW,Delhaes F,Mathers K,Zhao L,Vanderboor CMG,Regnault TRH
33-9100 was used in Immunocytochemistry to characterize the direct impact of a prolonged and isolated exposure to the dietary fatty acids Palmitate (PA) and Oleate (OA) upon placental cell mitochondrial respiratory function.
Fri Jan 01 00:00:00 EST 2021
Novel chicken two-dimensional intestinal model comprising all key epithelial cell types and a mesenchymal sub-layer.
Veterinary research
Orr B,Sutton K,Christian S,Nash T,Niemann H,Hansen LL,McGrew MJ,Jensen SR,Vervelde L
33-9100 was used in Immunocytochemistry-immunoflourescence to present an optimised protocol to generate chicken 2D enteroids that contain all major differentiated epithelial cell lineages and a self-organised sub-epithelial mesenchymal layer.
Wed Nov 24 00:00:00 EST 2021
Transplantation of GMP-grade human iPSC-derived retinal pigment epithelial cells in rodent model: the first pre-clinical study for safety and efficacy in China.
Annals of translational medicine
Zhang H,Su B,Jiao L,Xu ZH,Zhang CJ,Nie J,Gao ML,Zhang YV,Jin ZB
33-9100 was used in Immunohistochemistry (PFA fixed) to provide further evidence for the use of human iRPE transplantation to treat retinal degenerative disease in pre-clinical animal models.
Mon Feb 01 00:00:00 EST 2021
Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy.
The Korean journal of internal medicine
Kim JW,Nam SA,Seo E,Lee JY,Kim D,Ju JH,Lim SW,Kim HL,Kim HW,Yang CW,Kim J,Kim DS,Kim YK
33-9100 was used in Immunocytochemistry to model tacrolimus nephrotoxicity using kidney organoids derived from human inducible pluripotent stem cells (iPSCs) in vitro.
Mon Nov 01 00:00:00 EDT 2021
Regulation of Intestinal Epithelial Barrier and Immune Function by Activated T Cells.
Cellular and molecular gastroenterology and hepatology
Le N,Mazahery C,Nguyen K,Levine AD
33-9100 was used in Immunocytochemistry to conclude that bidirectional communication between T cells and epithelium mediates a biphasic response in barrier integrity that is facilitated by the balance between structural proteins partitioning in the mobile lateral phase vs the tight junction complex and cell morphology.
Mon Dec 20 00:00:00 EST 2021
MAP Kinase Pathways in Brain Endothelial Cells and Crosstalk with Pericytes and Astrocytes Mediate Contrast-Induced Blood-Brain Barrier Disruption.
Pharmaceutics
Matsunaga Y,Nakagawa S,Morofuji Y,Dohgu S,Watanabe D,Horie N,Izumo T,Niwa M,Walter FR,Santa-Maria AR,Deli MA,Matsuo T
33-9100 was used in Immunocytochemistry-immunoflourescence to investigate the effect of contrast media on blood-brain barrier (BBB) integrity.
Tue Aug 17 00:00:00 EDT 2021
Blood-Brain Barrier Permeability: Is 5-Hydroxytryptamine Receptor Type 4 a Game Changer?
Pharmaceutics
Becker G,Da Silva S,Sabo AN,Antal MC,Kemmel V,Monassier L
33-9100 was used in Western Blot to show that the 5-HT4 receptor contributes to the regulation of BBB permeability.
Wed Nov 03 00:00:00 EDT 2021
Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures.
eLife
Gkatzis K,Panza P,Peruzzo S,Stainier DY
33-9100 was used in Immunocytochemistry to understand how serum-free culture conditions effect alveolar cell differentiation into mouse-modelled lung organoids.
Wed Sep 29 00:00:00 EDT 2021
Lactic Acid-Producing Probiotic Saccharomyces cerevisiae Attenuates Ulcerative Colitis via Suppressing Macrophage Pyroptosis and Modulating Gut Microbiota.
Frontiers in immunology
Sun S,Xu X,Liang L,Wang X,Bai X,Zhu L,He Q,Liang H,Xin X,Wang L,Lou C,Cao X,Chen X,Li B,Wang B,Zhao J
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to show that lactic acid biosynthesis pathway that directly produces lactic acid from glucose rather than ethanol with high production was reconstructed in Saccharomyces cerevisiae.
Wed Feb 16 00:00:00 EST 2022
Salidroside Ameliorated Intermittent Hypoxia-Aggravated Endothelial Barrier Disruption and Atherosclerosis via the cAMP/PKA/RhoA Signaling Pathway.
Frontiers in pharmacology
Li L,Yang Y,Zhang H,Du Y,Jiao X,Yu H,Wang Y,Lv Q,Li F,Sun Q,Qin Y
33-9100 was used in Immunocytochemistry to demonstrate that salidroside effectively ameliorated IH-aggravated endothelial barrier injury and atherosclerosis, largely through the cAMP/PKA/RhoA signaling pathway.
Sat Sep 11 00:00:00 EDT 2021
Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism.
eLife
Pulgar E,Schwayer C,Guerrero N,López L,Márquez S,Härtel S,Soto R,Heisenberg CP,Concha ML
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to uncover a mechanism of progenitor cell allocation that stems from an incomplete process of epithelial delamination that allows progenitors to coordinate their movement with adjacent extra-embryonic tissues.
Fri Aug 27 00:00:00 EDT 2021
Extracellular Matrix Optimization for Enhanced Physiological Relevance in Hepatic Tissue-Chips.
Polymers
Chethikkattuveli Salih AR,Hyun K,Asif A,Soomro AM,Farooqi HMU,Kim YS,Kim KH,Lee JW,Huh D,Choi KH
33-9100 was used in Immunocytochemistry to show that standardized ECM type for MPS may improve clinical relevance for modeling hepatic tissue microenvironment, and image processing possibly enhance the tissue analysis of the MPS.
Mon Sep 06 00:00:00 EDT 2021
A comparative analysis of SARS-CoV-2 antivirals in human airway models characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19.
bioRxiv : the preprint server for biology
de Vries M,Mohamed AS,Prescott RA,Valero-Jimenez AM,Desvignes L,O'Connor R,Steppan C,Devlin JC,Ivanova E,Herrera A,Schinlever A,Loose P,Ruggles K,Koralov SB,Anderson AS,Binder J,Dittmann M
33-9100 was used in Immunocytochemistry-immunoflourescence to provide in vitro evidence for the potential of PF-00835231 as an effective antiviral for SARS-CoV-2, addresses concerns from non-human in vitro models, and supports further studies with this compound.
Fri Feb 19 00:00:00 EST 2021
Asymmetric distribution of dynamin-2 and β-catenin relative to tight junction spikes in alveolar epithelial cells.
Tissue barriers
Lynn KS,Easley KF,Martinez FJ,Reed RC,Schlingmann B,Koval M
33-9100 was used in Immunocytochemistry-immunofluorescence to suggest a novel role for dynamin-2 in tight junction spike formation by reorienting junction-associated actin.
Sat Jul 03 00:00:00 EDT 2021
TRIP6 is required for tension at adherens junctions.
Journal of cell science
Venkatramanan S,Ibar C,Irvine KD
33-9100 was used in Immunocytochemistry to identify a role for TRIP6 in organizing F-actin and maintaining tension at adherens junctions that could account for its influence on LIMD1 and LATS.
Thu Mar 11 00:00:00 EST 2021
Establishment of Intestinal Epithelial Cell Monolayers and Their Use in Calcium Switch Assay for Assessment of Intestinal Tight Junction Assembly.
Methods in molecular biology (Clifton, N.J.)
Pongkorpsakol P,Satianrapapong W,Wongkrasant P,Steinhagen PR,Tuangkijkul N,Pathomthongtaweechai N,Muanprasat C
33-9100 was used in Immunocytochemistry to provide a stepwise protocol for culture of intestinal epithelial cell monolayers using T84 cell line as an in vitro model and the Ca2+-switch assay for evaluating tight junction assembly.
Wed Jan 12 00:00:00 EST 2022
Opposing effects of Wnt/β-catenin signaling on epithelial and mesenchymal cell fate in the developing cochlea.
Development (Cambridge, England)
Billings SE,Myers NM,Quiruz L,Cheng AG
33-9100 was used in Immunohistochemistry to show that Wnt activation drives transition between epithelial and mesenchymal states in a cell type-dependent manner.
Tue Jun 01 00:00:00 EDT 2021
Increased In Vitro Intercellular Barrier Function of Lung Epithelial Cells Using Adipose-Derived Mesenchymal Stem/Stromal Cells.
Pharmaceutics
Ishii M,Tsuchiya T,Doi R,Morofuji Y,Fujimoto T,Muto H,Suematsu T,Mori R,Matsumoto K,Miyazaki T,Tomoshige K,Watanabe H,Iwatake M,Nagayasu T
33-9100 was used in Immunocytochemistry-immunoflourescence to show that AD-MSCs enhance the barrier function between lung epithelial cells.
Mon Aug 16 00:00:00 EDT 2021
Expression of SARS-CoV-2-related receptors in cells of the neurovascular unit: implications for HIV-1 infection.
Journal of neuroinflammation
Torices S,Cabrera R,Stangis M,Naranjo O,Fattakhov N,Teglas T,Adesse D,Toborek M
33-9100 was used in Western Blot to analyse the expression pattern of the main SARS-CoV-2 receptors in naïve and HIV-1-infected cells of the neurovascular unit in order to elucidate a possible pathway of the virus entry into the brain and a potential modulatory impact of HIV-1 in this process.
Thu Jul 29 00:00:00 EDT 2021
Substrate membrane bearing close-packed array of micron-level pillars incrassates air-exposed three-dimensional epidermal equivalent model.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
Kumamoto J,Fujimoto K,Kobayashi Y,Ohno K,Nagayama M,Denda M
33-9100 was used in Immunocytochemistry to evaluate epidermal equivalents built on a series of porous plastic membranes bearing arrays of pillars 15 µm, 20 µm, 25 µm, 30 µm, and 50 µm in diameter.
Wed Sep 01 00:00:00 EDT 2021
Pathology of the neurovascular unit in leukodystrophies.
Acta neuropathologica communications
Zarekiani P,Breur M,Wolf NI,de Vries HE,van der Knaap MS,Bugiani M
33-9100 was used in Immunohistochemistry (Paraffin) to provide further evidence for dysfunction in the orchestration of the neurovascular unit in leukodystrophies and contribute to a better understanding of the underlying disease mechanism.
Thu Jun 03 00:00:00 EDT 2021
The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos.
eLife
Morgani SM,Su J,Nichols J,Massagué J,Hadjantonakis AK
33-9100 was used in Immunohistochemistry to determine that ras-responsive element-binding protein 1 is essential for mouse embryonic development, with a possible role in cancer and diseases involving loss of epithelial integrity.
Fri Apr 30 00:00:00 EDT 2021
Tumor Necrosis Factor Alpha Effects on the Porcine Intestinal Epithelial Barrier Include Enhanced Expression of TNF Receptor 1.
International journal of molecular sciences
Droessler L,Cornelius V,Markov AG,Amasheh S
33-9100 was used in Western Blot, Immunohistochemistry to analyze functional, molecular and regulatory effects of Tumor necrosis factor alpha (TNFα) in a newly established non-transformed jejunal enterocyte model, namely IPEC-J2 monolayers.
Sat Aug 14 00:00:00 EDT 2021
Tumor Necrosis Factor Alpha Effects on the Porcine Intestinal Epithelial Barrier Include Enhanced Expression of TNF Receptor 1.
International journal of molecular sciences
Droessler L,Cornelius V,Markov AG,Amasheh S
33-9100 was used in Western Blot, Immunohistochemistry to analyze functional, molecular and regulatory effects of Tumor necrosis factor alpha (TNFα) in a newly established non-transformed jejunal enterocyte model, namely IPEC-J2 monolayers.
Sat Aug 14 00:00:00 EDT 2021
Localization and regulation of claudin-14 in experimental models of hypercalcemia.
American journal of physiology. Renal physiology
Frische S,Alexander RT,Ferreira P,Tan RSG,Wang W,Svenningsen P,Skjødt K,Dimke H
33-9100 was used in Immunohistochemistry to suggest that LacZ activity cannot be used as a marker for CLDN14 localization and regulation in this model.
Fri Jan 01 00:00:00 EST 2021
Synergy in Cystic Fibrosis Therapies: Targeting SLC26A9.
International journal of molecular sciences
Pinto MC,Quaresma MC,Silva IAL,Railean V,Ramalho SS,Amaral MD
33-9100 was used in Immunohistochemistry to investigate SLC26A9 as a target for treatment of respiratory disorders.
Thu Dec 02 00:00:00 EST 2021
Electrical synaptic transmission requires a postsynaptic scaffolding protein.
eLife
Lasseigne AM,Echeverry FA,Ijaz S,Michel JC,Martin EA,Marsh AJ,Trujillo E,Marsden KC,Pereda AE,Miller AC
33-9100 was used in Immunoprecipitation, Immunohistochemistry to investigate the functional role of Zonula Occludens 1 in zebrafish by examining identifiable synaptic contacts of the Mauthner cell which forms stereotyped electrical synapses accessible to genetic, biochemical, cell biological, electrophysiological, and behavioral analyses.
Wed Apr 28 00:00:00 EDT 2021
Electrical synaptic transmission requires a postsynaptic scaffolding protein.
eLife
Lasseigne AM,Echeverry FA,Ijaz S,Michel JC,Martin EA,Marsh AJ,Trujillo E,Marsden KC,Pereda AE,Miller AC
33-9100 was used in Immunoprecipitation, Immunohistochemistry to investigate the functional role of Zonula Occludens 1 in zebrafish by examining identifiable synaptic contacts of the Mauthner cell which forms stereotyped electrical synapses accessible to genetic, biochemical, cell biological, electrophysiological, and behavioral analyses.
Wed Apr 28 00:00:00 EDT 2021
Zika virus disrupts the barrier structure and Absorption/Secretion functions of the epididymis in mice.
PLoS neglected tropical diseases
Sheng Z,Gao N,Fan D,Wu N,Zhang Y,Han D,Zhang Y,Tan W,Wang P,An J
33-9100 was used in Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen) to assess the pathogenesis of ZIKV in the infected mice after footpad inoculation.
Mon Mar 01 00:00:00 EST 2021
Zika virus disrupts the barrier structure and Absorption/Secretion functions of the epididymis in mice.
PLoS neglected tropical diseases
Sheng Z,Gao N,Fan D,Wu N,Zhang Y,Han D,Zhang Y,Tan W,Wang P,An J
33-9100 was used in Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen) to assess the pathogenesis of ZIKV in the infected mice after footpad inoculation.
Mon Mar 01 00:00:00 EST 2021
Expression of E-Cadherin in Epithelial Cancer Cells Increases Cell Motility and Directionality through the Localization of ZO-1 during Collective Cell Migration.
Bioengineering (Basel, Switzerland)
Park SY,Jang H,Kim SY,Kim D,Park Y,Kee SH
33-9100 was used in Western Blot to examine cell motility using micropatterned free edge migration model with E-cadherin re-expressing EC96 cells derived from adenocarcinoma gastric (AGS) cell line.
Tue May 11 00:00:00 EDT 2021
Expression of E-Cadherin in Epithelial Cancer Cells Increases Cell Motility and Directionality through the Localization of ZO-1 during Collective Cell Migration.
Bioengineering (Basel, Switzerland)
Park SY,Jang H,Kim SY,Kim D,Park Y,Kee SH
33-9100 was used in Western Blot to examine cell motility using micropatterned free edge migration model with E-cadherin re-expressing EC96 cells derived from adenocarcinoma gastric (AGS) cell line.
Tue May 11 00:00:00 EDT 2021
CDKN2A-Mutated Pancreatic Ductal Organoids from Induced Pluripotent Stem Cells to Model a Cancer Predisposition Syndrome.
Cancers
Merkle J,Breunig M,Schmid M,Allgöwer C,Krüger J,Melzer MK,Bens S,Siebert R,Perkhofer L,Azoitei N,Seufferlein T,Heller S,Meier M,Müller M,Kleger A,Hohwieler M
33-9100 was used in Immunohistochemistry to provide a model for hereditary human pancreatic cancer that enables dissection of tumor initiation and early development starting from patient-specific CDKN2A-mutated pluripotent stem cells.
Wed Oct 13 00:00:00 EDT 2021
Differential Mechanisms of Action and Efficacy of Vitamin E Components in Antioxidant Cytoprotection of Human Retinal Pigment Epithelium.
Frontiers in pharmacology
Duncan RS,Hurtado DT,Hall CW,Koulen P
33-9100 was used in Immunocytochemistry to demonstrate that α-tocopherol (unlike γ-tocopherol and δ-tocopherol) appears to be unique in its requirement for transport and/or signaling for it to be an effective antioxidant.
Wed Mar 09 00:00:00 EST 2022
The Structure of the Spinal Cord Ependymal Region in Adult Humans Is a Distinctive Trait among Mammals.
Cells
Torrillas de la Cal A,Paniagua-Torija B,Arevalo-Martin A,Faulkes CG,Jiménez AJ,Ferrer I,Molina-Holgado E,Garcia-Ovejero D
33-9100 was used in Immunohistochemistry to suggest that canal patency is lost by delamination of the ependymal epithelium, in a process that includes apical polarity loss and the expression of signaling mediators involved in epithelial to mesenchymal transitions.
Sat Aug 28 00:00:00 EDT 2021
Cryptosporidium rhoptry effector protein ROP1 injected during invasion targets the host cytoskeletal modulator LMO7.
Cell host & microbe
Guérin A,Roy NH,Kugler EM,Berry L,Burkhardt JK,Shin JB,Striepen B
33-9100 was used in Immunocytochemistry-immunofluorescence to delineate the events of host cell invasion and uncover a mechanism unique to Cryptosporidium.
Wed Sep 08 00:00:00 EDT 2021
Butyrate Alleviates Cytokine-Induced Barrier Dysfunction by Modifying Claudin-2 Levels.
Biology
Huang X,Oshima T,Tomita T,Fukui H,Miwa H
33-9100 was used in Western Blot to suggest that butyrate is the main component of SCFAs to alleviate barrier dysfunction and that claudin-2 is the major target of this SCFA.
Tue Mar 09 00:00:00 EST 2021
LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images.
BMC biology
Herbert S,Valon L,Mancini L,Dray N,Caldarelli P,Gros J,Esposito E,Shorte SL,Bally-Cuif L,Aulner N,Levayer R,Tinevez JY
33-9100 was used in Immunohistochemistry to study the impact of geometrical distortions on morphological measurements induced by the projection.
Fri Jul 02 00:00:00 EDT 2021
Dynamic spatiotemporal coordination of neural stem cell fate decisions occurs through local feedback in the adult vertebrate brain.
Cell stem cell
Dray N,Mancini L,Binshtok U,Cheysson F,Supatto W,Mahou P,Bedu S,Ortica S,Than-Trong E,Krecsmarik M,Herbert S,Masson JB,Tinevez JY,Lang G,Beaurepaire E,Sprinzak D,Bally-Cuif L
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to highlight how local and temporally delayed interactions occurring between brain germinal cells generate self-propagating dynamics that maintain NSC population homeostasis and coordinate specific spatiotemporal correlations.
Thu Aug 05 00:00:00 EDT 2021
Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS.
Acta neuropathologica communications
Waters S,Swanson MEV,Dieriks BV,Zhang YB,Grimsey NL,Murray HC,Turner C,Waldvogel HJ,Faull RLM,An J,Bowser R,Curtis MA,Dragunow M,Scotter E
33-9100 was used in Immunohistochemistry (Paraffin) to suggest that blood-spinal cord barrier leakage and TDP-43 pathology are independent pathologies in amyotrophic lateral sclerosis.
Thu Aug 26 00:00:00 EDT 2021
Dynamic flow and shear stress as key parameters for intestinal cells morphology and polarization in an organ-on-a-chip model.
Biomedical microdevices
Fois CAM,Schindeler A,Valtchev P,Dehghani F
33-9100 was used in Immunocytochemistry-immunofluorescence to investigate the use of dynamic flow rates in gut-on-a-chip microfluidic devices, which allows for a constant cell shear stress (τc) while promoting faster cell polarization and differentiation of Caco-2 cells.
Sat Oct 16 00:00:00 EDT 2021
A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke.
Nature biomedical engineering
Lyu Z,Park J,Kim KM,Jin HJ,Wu H,Rajadas J,Kim DH,Steinberg GK,Lee W
33-9100 was used in Immunocytochemistry to report the development and applicability of a functional neurovascular unit on a microfluidic chip as a microphysiological model of ischaemic stroke that recapitulates the function of the blood-brain barrier as well as interactions between therapeutic stem cells and host cells (human brain microvascular endothelial cells, pericytes, astrocytes, microglia and neurons).
Sun Aug 01 00:00:00 EDT 2021
Centrosome anchoring regulates progenitor properties and cortical formation.
Nature
Shao W,Yang J,He M,Yu XY,Lee CH,Yang Z,Joyner AL,Anderson KV,Zhang J,Tsou MB,Shi H,Shi SH
33-9100 was used in Immunohistochemistry to indicate a previously unknown role of the centrosome in regulating the mechanical features of neural progenitor cells and the size and configuration of the mammalian cerebral cortex.
Wed Apr 01 00:00:00 EDT 2020
ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
Circulation research
Dai W,Nadadur RD,Brennan JA,Smith HL,Shen KM,Gadek M,Laforest B,Wang M,Gemel J,Li Y,Zhang J,Ziman BD,Yan J,Ai X,Beyer EC,Lakata EG,Kasthuri N,Efimov IR,Broman MT,Moskowitz IP,Shen L,Weber CR
33-9100 was used in Immunohistochemistry to determine the role of ZO-1 in cardiac function.
Fri Jul 03 00:00:00 EDT 2020
ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
Circulation research
Dai W,Nadadur RD,Brennan JA,Smith HL,Shen KM,Gadek M,Laforest B,Wang M,Gemel J,Li Y,Zhang J,Ziman BD,Yan J,Ai X,Beyer EC,Lakata EG,Kasthuri N,Efimov IR,Broman MT,Moskowitz IP,Shen L,Weber CR
33-9100 was used in Immunohistochemistry to determine the role of ZO-1 in cardiac function.
Fri Jul 03 00:00:00 EDT 2020
Light-responsive microRNA miR-211 targets Ezrin to modulate lysosomal biogenesis and retinal cell clearance.
The EMBO journal
Naso F,Intartaglia D,Falanga D,Soldati C,Polishchuk E,Giamundo G,Tiberi P,Marrocco E,Scudieri P,Di Malta C,Trapani I,Nusco E,Salierno FG,Surace EM,Galietta LJ,Banfi S,Auricchio A,Ballabio A,Medina DL,Conte I
33-9100 was used in Immunocytochemistry to show that the light-responsive miR-211 controls lysosomal biogenesis at the beginning of light-dark transitions in the RPE by targeting Ezrin, a cytoskeleton-associated protein essential for the regulation of calcium homeostasis.
Wed Apr 15 00:00:00 EDT 2020
Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected.
Proceedings of the National Academy of Sciences of the United States of America
Liu C,Miyajima T,Melangath G,Miyai T,Vasanth S,Deshpande N,Kumar V,Ong Tone S,Gupta R,Zhu S,Vojnovic D,Chen Y,Rogan EG,Mondal B,Zahid M,Jurkunas UV
33-9100 was used in Immunohistochemistry to establish a nongenetic FECD animal model based on the physiologic outcome of CE susceptibility to oxidative stress by demonstrating that corneal exposure to ultraviolet A (UVA) recapitulates the morphological and molecular changes of FECD.
Tue Jan 07 00:00:00 EST 2020
P7C3-A20 treatment one year after TBI in mice repairs the blood-brain barrier, arrests chronic neurodegeneration, and restores cognition.
Proceedings of the National Academy of Sciences of the United States of America
Vázquez-Rosa E,Shin MK,Dhar M,Chaubey K,Cintrón-Pérez CJ,Tang X,Liao X,Miller E,Koh Y,Barker S,Franke K,Crosby DR,Schroeder R,Emery J,Yin TC,Fujioka H,Reynolds JD,Harper MM,Jain MK,Pieper AA
33-9100 was used in Western Blotting to report that pharmacologic restoration of the blood-brain barrier (BBB), 12 mo after murine TBI, is associated with arrested axonal neurodegeneration and cognitive recovery, benefits that persisted for months after treatment cessation.
Tue Nov 03 00:00:00 EST 2020
Unlocking the Potential of Organ-on-Chip Models through Pumpless and Tubeless Microfluidics.
Advanced healthcare materials
Delon LC,Nilghaz A,Cheah E,Prestidge C,Thierry B
33-9100 was used in Immunocytochemistry to report a novel approach to manufacture pumpless and tubeless organs-on-chips.
Mon Jun 01 00:00:00 EDT 2020
The Reissner Fiber Is Highly Dynamic In Vivo and Controls Morphogenesis of the Spine.
Current biology : CB
Troutwine BR,Gontarz P,Konjikusic MJ,Minowa R,Monstad-Rios A,Sepich DS,Kwon RY,Solnica-Krezel L,Gray RS
33-9100 was used in Immunohistochemistry (PFA fixed) to describe hypomorphic missense mutations of scospondin, which allow Reissner fiber assembly and extension of a straight axis.
Mon Jun 22 00:00:00 EDT 2020
Sensory Neurons Contacting the Cerebrospinal Fluid Require the Reissner Fiber to Detect Spinal Curvature In Vivo.
Current biology : CB
Orts-Del'Immagine A,Cantaut-Belarif Y,Thouvenin O,Roussel J,Baskaran A,Langui D,Koëth F,Bivas P,Lejeune FX,Bardet PL,Wyart C
33-9100 was used in Immunohistochemistry (PFA fixed) to uncover that neurons contacting the cerebrospinal fluid functionally interact with the RF to detect spinal curvature in the vertebrate spinal cord.
Mon Mar 09 00:00:00 EDT 2020
Lipopolysaccharides modulate intestinal epithelial permeability and inflammation in a species-specific manner.
Gut microbes
Stephens M,von der Weid PY
33-9100 was used in Immunocytochemistry-immunoflourescence to suggest that specific species of bacteria may be potentiating the pathogenesis of IBD and chronic inflammatory diseases through their serotype specific LPS responses.
Sun May 03 00:00:00 EDT 2020
Adenoviral protein E4orf4 interacts with the polarity protein Par3 to induce nuclear rupture and tumor cell death.
The Journal of cell biology
Dziengelewski C,Rodrigue MA,Caillier A,Jacquet K,Boulanger MC,Bergeman J,Fuchs M,Lambert H,Laprise P,Richard DE,Bordeleau F,Huot MÉ,Lavoie JN
33-9100 was used in Western Blotting to show that the tumoricidal effect of E4orf4 is typified by changes in nuclear dynamics that depend on its interaction with the polarity protein Par3 and actomyosin contractility.
Mon Apr 06 00:00:00 EDT 2020
S100A4+ macrophages facilitate zika virus invasion and persistence in the seminiferous tubules via interferon-gamma mediation.
PLoS pathogens
Yang W,Wu YH,Liu SQ,Sheng ZY,Zhen ZD,Gao RQ,Cui XY,Fan DY,Qin ZH,Zheng AH,Wang PG,An J
33-9100 was used in Immunohistochemistry-immunofluorescence to show that S100A4+ macrophages, a myeloid macrophage subpopulation with susceptibility to ZIKV infection, facilitated ZIKV invasion and persistence in the seminiferous tubules.
Tue Dec 01 00:00:00 EST 2020
Neonatal Hyperoxia Downregulates Claudin-4, Occludin, and ZO-1 Expression in Rat Kidney Accompanied by Impaired Proximal Tubular Development.
Oxidative medicine and cellular longevity
Xu X,Zhang X,Gao L,Liu C,You K
33-9100 was used in Western Blot, Immunohistochemistry to investigate how neonatal hyperoxia affected the expression of key tight junction proteins and inflammatory factors (IL-6 and TNF-α) in the developing rat kidneys and elucidated their correlation with renal injury.
Tue Sep 07 00:00:00 EDT 2021
Neonatal Hyperoxia Downregulates Claudin-4, Occludin, and ZO-1 Expression in Rat Kidney Accompanied by Impaired Proximal Tubular Development.
Oxidative medicine and cellular longevity
Xu X,Zhang X,Gao L,Liu C,You K
33-9100 was used in Western Blot, Immunohistochemistry to investigate how neonatal hyperoxia affected the expression of key tight junction proteins and inflammatory factors (IL-6 and TNF-α) in the developing rat kidneys and elucidated their correlation with renal injury.
Tue Sep 07 00:00:00 EDT 2021
Mitochondrial and Peroxisomal Alterations Contribute to Energy Dysmetabolism in Riboflavin Transporter Deficiency.
Oxidative medicine and cellular longevity
Colasuonno F,Niceforo A,Marioli C,Fracassi A,Stregapede F,Massey K,Tartaglia M,Bertini E,Compagnucci C,Moreno S
33-9100 was used in Immunocytochemistry to investigate morphofunctional features, focusing on mitochondrial and peroxisomal compartmentsinvestigate whether.
Fri May 14 00:00:00 EDT 2021
Fgfbp1 promotes blood-brain barrier development by regulating collagen IV deposition and maintaining Wnt/β-catenin signaling.
Development (Cambridge, England)
Cottarelli A,Corada M,Beznoussenko GV,Mironov AA,Globisch MA,Biswas S,Huang H,Dimberg A,Magnusson PU,Agalliu D,Lampugnani MG,Dejana E
33-9100 was used in Immunocytochemistry to conclude that Fgfbp1 is a crucial extracellular matrix protein during BBB maturation that regulates cell-cell interactions and Wnt/β-catenin activity.
Mon Aug 24 00:00:00 EDT 2020
Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube.
Development (Cambridge, England)
Symonds AC,Buckley CE,Williams CA,Clarke JDW
33-9100 was used in Immunohistochemistry (PFA fixed) to show that Mpp5a and Rab11a play a dual role in coordinating the generation of ipsilateral junctional belts whilst simultaneously releasing contralateral adhesions across the centre of the tissue.
Wed Dec 23 00:00:00 EST 2020
MMP14 is required for delamination of chick neural crest cells independently of its catalytic activity.
Development (Cambridge, England)
Andrieu C,Montigny A,Bibonne A,Despin-Guitard E,Alfandari D,Théveneau E
33-9100 was used in Immunohistochemistry (Frozen) to indicate that MMP14 is also likely to be an early player, owing to its role in EMT.
Sun Apr 12 00:00:00 EDT 2020
FTY720 Protects Against Ischemia-Reperfusion Injury by Preventing the Redistribution of Tight Junction Proteins and Decreases Inflammation in the Subacute Phase in an Experimental Stroke Model.
Translational stroke research
Wang Z,Higashikawa K,Yasui H,Kuge Y,Ohno Y,Kihara A,Midori YA,Houkin K,Kawabori M
33-9100 was used in Immunocytochemistry-immunoflourescence to show sphingosine-1-phosphate receptor agonist FTY720 can protect the blood-brain barrier and regulate neuroinflammation.
Thu Oct 01 00:00:00 EDT 2020
Signs of Reduced Basal Progenitor Levels and Cortical Neurogenesis in Human Fetuses with Open Spina Bifida at 11-15 Weeks of Gestation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Fietz SA,Namba T,Kirsten H,Huttner WB,Lachmann R
33-9100 was used in Immunocytochemistry-immunoflourescence to indicate that neocortex development in OSB fetuses is altered as early as 11 weeks of gestation.
Wed Feb 19 00:00:00 EST 2020
Midkine-a Is Required for Cell Cycle Progression of Müller Glia during Neuronal Regeneration in the Vertebrate Retina.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Nagashima M,D'Cruz TS,Danku AE,Hesse D,Sifuentes C,Raymond PA,Hitchcock PF
33-9100 was used in Immunohistochemistry-immunofluorescence to provide a unique insight into mechanisms that control the cell cycle during neuronal regeneration.
Wed Feb 05 00:00:00 EST 2020
Zebrafish Crb1, Localizing Uniquely to the Cell Membranes around Cone Photoreceptor Axonemes, Alleviates Light Damage to Photoreceptors and Modulates Cones' Light Responsiveness.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Guo C,Deveau C,Zhang C,Nelson R,Wei X
33-9100 was used in Immunohistochemistry to show that zebrafish Crb1 does not localize to the subapical regions of photoreceptors and Müller glial cells; rather, it localizes to a small region of cone outer segments: the cell membranes surrounding the axonemes.
Wed Sep 09 00:00:00 EDT 2020
CRISP3 expression drives prostate cancer invasion and progression.
Endocrine-related cancer
Volpert M,Furic L,Hu J,O'Connor AE,Rebello RJ,Keerthikumar S,Evans J,Merriner DJ,Pedersen J,Risbridger GP,McIntyre P,O'Bryan MK
33-9100 was used in Immunohistochemistry to identify if CRISP3 is pro-tumorigenic in the prostate and validate it as a potential target for therapeutic intervention.
Wed Jul 01 00:00:00 EDT 2020
CRISP3 expression drives prostate cancer invasion and progression.
Endocrine-related cancer
Volpert M,Furic L,Hu J,O'Connor AE,Rebello RJ,Keerthikumar S,Evans J,Merriner DJ,Pedersen J,Risbridger GP,McIntyre P,O'Bryan MK
33-9100 was used in Immunohistochemistry to identify if CRISP3 is pro-tumorigenic in the prostate and validate it as a potential target for therapeutic intervention.
Wed Jul 01 00:00:00 EDT 2020
Intestinal vitamin D receptor signaling ameliorates dextran sulfate sodium-induced colitis by suppressing necroptosis of intestinal epithelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Shi Y,Cui X,Sun Y,Zhao Q,Liu T
33-9100 was used in Western Blotting to offer some theoretical basis for a novel treatment of IBD in clinical practice.
Thu Oct 01 00:00:00 EDT 2020
Transplantation of iPS-derived vascular endothelial cells improves white matter ischemic damage.
Journal of neurochemistry
Xu B,Kurachi M,Shimauchi-Ohtaki H,Yoshimoto Y,Ishizaki Y
33-9100 was used in Immunohistochemistry (PFA fixed) to suggest that internal vascular endothelial cell transplantation can be used to treat demyelination and brain dysfunction cause by white matter infarct.
Mon Jun 01 00:00:00 EDT 2020
Palmitic acid damages gut epithelium integrity and initiates inflammatory cytokine production.
Biochimica et biophysica acta. Molecular and cell biology of lipids
Ghezzal S,Postal BG,Quevrain E,Brot L,Seksik P,Leturque A,Thenet S,Carrière V
33-9100 was used in Simple Western - Size to show that short exposure to palm oil or palmitic acid induces intestinal dysfunctions targeting barrier integrity and inflammation.
Sat Feb 01 00:00:00 EST 2020
Insulin-like growth factor 1 triggers salt secretion machinery in fish under acute salinity stress.
The Journal of endocrinology
Yan JJ,Lee YC,Tsou YL,Tseng YC,Hwang PP
33-9100 was used in Immunocytochemistry to study whether endocrine hormone, insulin-like growth factor 1, is involved in the activation of salt secretion mechanisms in euryhaline medaka during acclimation to acute salinity stress.
Tue Sep 01 00:00:00 EDT 2020
N‑glycosylation and receptor tyrosine kinase signaling affect claudin‑3 levels in colorectal cancer cells.
Oncology reports
Pérez AG,Andrade-Da-Costa J,De Souza WF,De Souza Ferreira M,Boroni M,De Oliveira IM,Freire-Neto CA,Fernandes PV,De Lanna CA,Souza-Santos PT,Morgado-Díaz JA,De-Freitas-Junior JCM
33-9100 was used in Western Blotting to identify a mechanism integrating receptor tyrosine kinase signalling and N-glycosylation for the regulation of claudin-3 levels in colorectal cancer.
Thu Oct 01 00:00:00 EDT 2020
Metformin and Inhibition of Transforming Growth Factor-Beta Stimulate In Vitro Transport in Primary Renal Tubule Cells.
Tissue engineering. Part A
Love H,Evans R,Humes HD,Roy S,Zent R,Harris R,Wilson M,Fissell WH
33-9100 was used in Immunocytochemistry-immunoflourescence to show that addition of metformin increased transport, in the context of a transient effect on 5' AMP-activated kinase phosphorylation.
Thu Oct 01 00:00:00 EDT 2020
The HIF target ATG9A is essential for epithelial barrier function and tight junction biogenesis.
Molecular biology of the cell
Dowdell AS,Cartwright IM,Goldberg MS,Kostelecky R,Ross T,Welch N,Glover LE,Colgan SP
33-9100 was used in Immunocytochemistry to identify HIF transcriptional targets in Intestinal epithelial cells.
Tue Sep 15 00:00:00 EDT 2020
Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion.
Molecular biology of the cell
Teo JL,Tomatis VM,Coburn L,Lagendijk AK,Schouwenaar IM,Budnar S,Hall TE,Verma S,McLachlan RW,Hogan BM,Parton RG,Yap AS,Gomez GA
33-9100 was used in Immunocytochemistry to report a complementary process of cytoskeletal relaxation that occurs when cortical contractility is down-regulated at the junctions between those neighbor cells themselves.
Sun Nov 01 00:00:00 EDT 2020
Going Back and Forth: Episomal Vector Reprogramming of Peripheral Blood Mononuclear Cells to Induced Pluripotent Stem Cells and Subsequent Differentiation into Cardiomyocytes and Neuron-Astrocyte Co-cultures.
Cellular reprogramming
de Leeuw VC,van Oostrom CTM,Imholz S,Piersma AH,Hessel EVS,Dollé MET
33-9100 was used in Immunocytochemistry to reprogramme PBMCs into iPSCs and studied their pluripotent nature.
Tue Dec 01 00:00:00 EST 2020
Culture of Intestinal Epithelial Cell Monolayers and Their Use in Multiplex Macromolecular Permeability Assays for In Vitro Analysis of Tight Junction Size Selectivity.
Current protocols in immunology
Pongkorpsakol P,Turner JR,Zuo L
33-9100 was used in Immunohistochemistry to describe methods for culturing intestinal epithelial cell monolayers and assessing the impact of cytokine treatment on leak and unrestricted pathway permeabilities.
Tue Dec 01 00:00:00 EST 2020
Tightening the retinal glia limitans attenuates neuroinflammation after optic nerve injury.
Glia
Lefevere E,Salinas-Navarro M,Andries L,Noterdaeme L,Etienne I,Van Wonterghem E,Vinckier S,Davis BM,Van Bergen T,Van Hove I,Movahedi K,Vandenbroucke RE,Moons L,De Groef L
33-9100 was used in Western Blotting to investigate the structure and function of the glia limitans, and reveal that the blood-retina barrier and glia limitans function as a coordinated double barrier to limit infiltration of leukocytes and immune molecules.
Tue Dec 01 00:00:00 EST 2020
Origin and role of the cerebrospinal fluid bidirectional flow in the central canal.
eLife
Thouvenin O,Keiser L,Cantaut-Belarif Y,Carbo-Tano M,Verweij F,Jurisch-Yaksi N,Bardet PL,van Niel G,Gallaire F,Wyart C
33-9100 was used in Immunohistochemistry to demonstrate that cilia activity combined with muscle contractions sustain the long-range transport of extracellular lipidic particles, enabling embryonic growth.
Thu Jan 09 00:00:00 EST 2020
Stepwise polarisation of developing bilayered epidermis is mediated by aPKC and E-cadherin in zebrafish.
eLife
Arora P,Dongre S,Raman R,Sonawane M
33-9100 was used in Immunohistochemistry to suggest that peridermal polarity is initiated by aPKC and is transduced stepwise by E-cadherin to the basal layer in zebrafish.
Wed Jan 22 00:00:00 EST 2020
The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification.
PLoS genetics
Cross SH,Mckie L,Hurd TW,Riley S,Wills J,Barnard AR,Young F,MacLaren RE,Jackson IJ
33-9100 was used in Immunohistochemistry to show eye size is dependent on a crucial interplay between TMEM98 and MYRF.
Wed Apr 01 00:00:00 EDT 2020
Tau reduction in aged mice does not impact Microangiopathy.
Acta neuropathologica communications
Bennett RE,Hu M,Fernandes A,Perez-Rando M,Robbins A,Kamath T,Dujardin S,Hyman BT
33-9100 was used in Immunocytochemistry to understand the nature of tau-related microangiopathy in human AD and in tau mice and examine whether this soluble tau is directly responsible for the microangiopathic changes.
Tue Aug 18 00:00:00 EDT 2020
Intestinal vitamin D receptor knockout protects from oxazolone-induced colitis.
Cell death & disease
Shi Y,Liu Z,Cui X,Zhao Q,Liu T
33-9100 was used in Western Blotting to identify that intestinal vitamin D receptor knockout protected against oxazolone-induced colitis in mice by blocking Th2 cell response and reducing the function of intestinal invariant natural killer T cells.
Mon Jun 15 00:00:00 EDT 2020
Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids.
International journal of molecular sciences
Workman MJ,Troisi E,Targan SR,Svendsen CN,Barrett RJ
33-9100 was used in Western Blot, Immunocytochemistry to characterize the response to IFN-γ in HIOs derived from induced pluripotent stem cells (iPSCs).
Wed Dec 30 00:00:00 EST 2020
Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids.
International journal of molecular sciences
Workman MJ,Troisi E,Targan SR,Svendsen CN,Barrett RJ
33-9100 was used in Western Blot, Immunocytochemistry to characterize the response to IFN-γ in HIOs derived from induced pluripotent stem cells (iPSCs).
Wed Dec 30 00:00:00 EST 2020
Crosstalk between Long-Term Sublethal Oxidative Stress and Detrimental Inflammation as Potential Drivers for Age-Related Retinal Degeneration.
Antioxidants (Basel, Switzerland)
Macchioni L,Chiasserini D,Mezzasoma L,Davidescu M,Orvietani PL,Fettucciari K,Salviati L,Cellini B,Bellezza I
33-9100 was used in Immunocytochemistry to indicate senescence as an important link between chronic oxidative insult and detrimental chronic inflammation, with possible future repercussions for therapeutic interventions.
Tue Dec 29 00:00:00 EST 2020
Prothymosin alpha and its mimetic hexapeptide improve delayed tissue plasminogen activator-induced brain damage following cerebral ischemia.
Journal of neurochemistry
Halder SK,Matsunaga H,Ueda H
33-9100 was used in Western Blotting to examine the beneficial effects of ProTα or P6Q against delayed tPA-induced brain damage following middle cerebral artery occlusion (MCAO) or photochemically induced thrombosis in mice.
Mon Jun 01 00:00:00 EDT 2020
Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model.
eLife
Kasendra M,Luc R,Yin J,Manatakis DV,Kulkarni G,Lucchesi C,Sliz J,Apostolou A,Sunuwar L,Obrigewitch J,Jang KJ,Hamilton GA,Donowitz M,Karalis K
33-9100 was used in Immunohistochemistry-immunofluorescence to combine organoids and Organs-onChips technology to create a human Duodenum Intestine-Chip that emulates intestinal tissue architecture and functions, that are relevant for the study of drug transport, metabolism, and drug-drug interactions(DDI).
Tue Jan 14 00:00:00 EST 2020
Laminin 221 fragment is suitable for the differentiation of human induced pluripotent stem cells into brain microvascular endothelial-like cells with robust barrier integrity.
Fluids and barriers of the CNS
Aoki H,Yamashita M,Hashita T,Iwao T,Matsunaga T
33-9100 was used in Immunocytochemistry-immunoflourescence to show that the LN221F-iBMELCs had more robust barrier function for a longer period than Matrigel-iBMELCs with characteristics of BMECs.
Mon Mar 30 00:00:00 EDT 2020
Laminin 221 fragment is suitable for the differentiation of human induced pluripotent stem cells into brain microvascular endothelial-like cells with robust barrier integrity.
Fluids and barriers of the CNS
Aoki H,Yamashita M,Hashita T,Iwao T,Matsunaga T
33-9100 was used in Immunocytochemistry-immunoflourescence to show that the LN221F-iBMELCs had more robust barrier function for a longer period than Matrigel-iBMELCs with characteristics of BMECs.
Mon Mar 30 00:00:00 EDT 2020
Mechanical forces drive ordered patterning of hair cells in the mammalian inner ear.
Nature communications
Cohen R,Amir-Zilberstein L,Hersch M,Woland S,Loza O,Taiber S,Matsuzaki F,Bergmann S,Avraham KB,Sprinzak D
33-9100 was used in Immunohistochemistry to show that the transition from disordered to ordered checkerboard-like pattern of hair cells and supporting cells in the mammalian hearing organ, the organ of Corti, is likely based on mechanical forces rather than signaling events.
Mon Oct 12 00:00:00 EDT 2020
Osmotic regulation of aquaporin-8 expression in retinal pigment epithelial cells in vitro: Dependence on KATP channel activation.
Molecular vision
Schnabel B,Kuhrt H,Wiedemann P,Bringmann A,Hollborn M
33-9100 was used in Immunocytochemistry to indicate that hyperosmotic expression of AQP8 in RPE cells is dependent on the activation of KATP channels.
Thu Aug 26 00:00:00 EDT 2021
AhR activation defends gut barrier integrity against damage occurring in obesity.
Molecular metabolism
Postal BG,Ghezzal S,Aguanno D,André S,Garbin K,Genser L,Brot-Laroche E,Poitou C,Soula H,Leturque A,Clément K,Carrière V
33-9100 was used in Immunocytochemistry to study the causal relationship between AhR activation and gut inflammation in obesity.
Tue Sep 01 00:00:00 EDT 2020
Apical Restriction of the Planar Cell Polarity Component VANGL in Pancreatic Ducts Is Required to Maintain Epithelial Integrity.
Cell reports
Flasse L,Yennek S,Cortijo C,Barandiaran IS,Kraus MR,Grapin-Botton A
33-9100 was used in Immunohistochemistry to show that apical restriction of planar cell polarity (PCP) components is necessary for the maintenance of epithelial integrity.
Tue May 26 00:00:00 EDT 2020
Amyloid-β Precursor Protein APP Down-Regulation Alters Actin Cytoskeleton-Interacting Proteins in Endothelial Cells.
Cells
Ristori E,Cicaloni V,Salvini L,Tinti L,Tinti C,Simons M,Corti F,Donnini S,Ziche M
33-9100 was used in Western Blot to identify and investigate major cellular targets of APP down-regulation in endothelial cells.
Thu Nov 19 00:00:00 EST 2020
Multiplexed analysis of neural cytokine signaling by a novel neural cell-cell interaction microchip.
Lab on a chip
Abdullah MAA,Amini N,Yang L,Paluh JL,Wang J
33-9100 was used in Immunocytochemistry-immunofluorescence to study NSC rosettes demonstrates the development, versatility and utility of the NCCIM as a sensitive multiplex detector of cytokine signaling in a high throughput and controlled microenvironment.
Sat Nov 07 00:00:00 EST 2020
Mannheimia haemolytica and lipopolysaccharide induce airway epithelial inflammatory responses in an extensively developed ex vivo calf model.
Scientific reports
Cai Y,Varasteh S,van Putten JPM,Folkerts G,Braber S
33-9100 was used in Western Blot, Immunocytochemistry to study mechanisms of epithelial airway inflammation and the effects of Mannheimia haemolytica and lipopolysaccharide on these inflammatory responses.
Mon Aug 03 00:00:00 EDT 2020
Mannheimia haemolytica and lipopolysaccharide induce airway epithelial inflammatory responses in an extensively developed ex vivo calf model.
Scientific reports
Cai Y,Varasteh S,van Putten JPM,Folkerts G,Braber S
33-9100 was used in Western Blot, Immunocytochemistry to study mechanisms of epithelial airway inflammation and the effects of Mannheimia haemolytica and lipopolysaccharide on these inflammatory responses.
Mon Aug 03 00:00:00 EDT 2020
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis.
Nature communications
Samson AL,Zhang Y,Geoghegan ND,Gavin XJ,Davies KA,Mlodzianoski MJ,Whitehead LW,Frank D,Garnish SE,Fitzgibbon C,Hempel A,Young SN,Jacobsen AV,Cawthorne W,Petrie EJ,Faux MC,Shield-Artin K,Lalaoui N,Hildebrand JM,Silke J,Rogers KL,Lessene G,Hawkins ED,Murphy JM
33-9100 was used in Immunocytochemistry-immunoflourescence to identify MLKL trafficking and plasma membrane accumulation as crucial necroptosis checkpoints.
Fri Jun 19 00:00:00 EDT 2020
Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish.
Scientific reports
Banote RK,Chebli J,Şatır TM,Varshney GK,Camacho R,Ledin J,Burgess SM,Abramsson A,Zetterberg H
33-9100 was used in Immunohistochemistry-immunofluorescence to investigate the biological function of amyloid beta (Aβ) precursor protein (APP) during embryonic development.
Tue Jun 23 00:00:00 EDT 2020
Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function.
Scientific reports
Findlay AS,McKie L,Keighren M,Clementson-Mobbs S,Sanchez-Pulido L,Wells S,Cross SH,Jackson IJ
33-9100 was used in Immunohistochemistry to show Fam151b mutant mice show signs of retinal stress and rapidly lose photoreceptor cells indicating an essential role in retinal function.
Thu Jan 16 00:00:00 EST 2020
16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development.
eLife
Roth JG,Muench KL,Asokan A,Mallett VM,Gai H,Verma Y,Weber S,Charlton C,Fowler JL,Loh KM,Dolmetsch RE,Palmer TD
33-9100 was used in Immunocytochemistry-immunoflourescence to reveal disruptions in gene programs related to both nervous system function and cellular metabolism.
Tue Nov 10 00:00:00 EST 2020
Mycotoxin Deoxynivalenol Has Different Impacts on Intestinal Barrier and Stem Cells by Its Route of Exposure.
Toxins
Hanyu H,Yokoi Y,Nakamura K,Ayabe T,Tanaka K,Uno K,Miyajima K,Saito Y,Iwatsuki K,Shimizu M,Tadaishi M,Kobayashi-Hattori K
33-9100 was used in Immunohistochemistry to explore the toxic effects of DON on intestinal barrier functions and stem cells after DON microinjection (luminal exposure) or addition to a culture medium (basolateral exposure) using three-dimensional mouse intestinal organoids (enteroids).
Thu Sep 24 00:00:00 EDT 2020
A Novel Formulation of Glucose-Sparing Peritoneal Dialysis Solutions with l-Carnitine Improves Biocompatibility on Human Mesothelial Cells.
International journal of molecular sciences
Piccapane F,Bonomini M,Castellano G,Gerbino A,Carmosino M,Svelto M,Arduini A,Procino G
33-9100 was used in Immunocytochemistry-immunofluorescence to report here compelling evidence that this novel formulation shows better performance in terms of higher cell viability, better preservation of the integrity of the mesothelial layer and reduced release of pro-inflammatory cytokines.
Thu Dec 24 00:00:00 EST 2020
Exposure to Zinc Oxide Nanoparticles Disrupts Endothelial Tight and Adherens Junctions and Induces Pulmonary Inflammatory Cell Infiltration.
International journal of molecular sciences
Chen CM,Wu ML,Ho YC,Gung PY,Tsai MH,Orekhov AN,Sobenin IA,Lin P,Yet SF
33-9100 was used in Immunocytochemistry to investigate the effects of zinc oxide nanoparticle exposure on vascular functions, particularly on endothelial barriers, using in vitro and in vivo models.
Wed May 13 00:00:00 EDT 2020
Host-Pathogen Responses to Pandemic Influenza H1N1pdm09 in a Human Respiratory Airway Model.
Viruses
Pharo EA,Williams SM,Boyd V,Sundaramoorthy V,Durr PA,Baker ML
33-9100 was used in Immunocytochemistry-immunoflourescence to demonstrate that wdNHBE cells are an appropriate ex-vivo model system to investigate the pathogenesis of respiratory viruses.
Wed Jun 24 00:00:00 EDT 2020
A Human Induced Pluripotent Stem Cell-Derived Isogenic Model of Huntington's Disease Based on Neuronal Cells Has Several Relevant Phenotypic Abnormalities.
Journal of personalized medicine
Malankhanova T,Suldina L,Grigor'eva E,Medvedev S,Minina J,Morozova K,Kiseleva E,Zakian S,Malakhova A
33-9100 was used in Immunocytochemistry to create a new isogenic induced pluripotent stem cell-based cell system that models Huntington's disease and recapitulates specific disturbances in the mutant cells.
Mon Nov 09 00:00:00 EST 2020
Retinal microglia are critical for subretinal neovascular formation.
JCI insight
Usui-Ouchi A,Usui Y,Kurihara T,Aguilar E,Dorrell MI,Ideguchi Y,Sakimoto S,Bravo S,Friedlander M
33-9100 was used in Immunocytochemistry to highlight the contribution of microglia/macrophages to the pathogenesis of neovascularization, provide valuable clues regarding potential causative cellular mechanisms for subretinal neovascularization in patients with MacTel and RAP and suggest that targeting microglia activation may be a therapeutic option in these diseases.
Thu Jun 18 00:00:00 EDT 2020
Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus.
Nature communications
Zhou X,Zhong S,Peng H,Liu J,Ding W,Sun L,Ma Q,Liu Z,Chen R,Wu Q,Wang X
33-9100 was used in Immunocytochemistry to study the neural progenitor cells within the developing hypothalamus and their cellular and functional properties using mouse and human data.
Thu Aug 13 00:00:00 EDT 2020
Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells.
Cell reports
Takeishi K,Collin de l'Hortet A,Wang Y,Handa K,Guzman-Lepe J,Matsubara K,Morita K,Jang S,Haep N,Florentino RM,Yuan F,Fukumitsu K,Tobita K,Sun W,Franks J,Delgado ER,Shapiro EM,Fraunhoffer NA,Duncan AW,Yagi H,Mashimo T,Fox IJ,Soto-Gutierrez A
33-9100 was used in Immunohistochemistry to developed protocols for hepatocyte-, cholangiocyte-, and endothelial-cell differentiation of human induced pluripotent stem cells (iPSCs).
Tue Jun 02 00:00:00 EDT 2020
Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells.
Cell reports
Takeishi K,Collin de l'Hortet A,Wang Y,Handa K,Guzman-Lepe J,Matsubara K,Morita K,Jang S,Haep N,Florentino RM,Yuan F,Fukumitsu K,Tobita K,Sun W,Franks J,Delgado ER,Shapiro EM,Fraunhoffer NA,Duncan AW,Yagi H,Mashimo T,Fox IJ,Soto-Gutierrez A
33-9100 was used in Immunohistochemistry to developed protocols for hepatocyte-, cholangiocyte-, and endothelial-cell differentiation of human induced pluripotent stem cells (iPSCs).
Tue Jun 02 00:00:00 EDT 2020
Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly.
Cell reports
Haas AJ,Zihni C,Ruppel A,Hartmann C,Ebnet K,Tada M,Balda MS,Matter K
33-9100 was used in Immunocytochemistry to investigate if tight junctions carry a mechanical load by using a tension sensor based on ZO-1.
Tue Jul 21 00:00:00 EDT 2020
Mechanical Stress Regulates Epithelial Tissue Integrity and Stiffness through the FGFR/Erk2 Signaling Pathway during Embryogenesis.
Cell reports
Kinoshita N,Hashimoto Y,Yasue N,Suzuki M,Cristea IM,Ueno N
33-9100 was used in Immunocytochemistry to demonstrate the role of FGFR/Erk2 signaling as a critical component in embryogenesis.
Tue Mar 17 00:00:00 EDT 2020
No tight junctions in tight junction protein-1 expressing HeLa and fibroblast cells.
International journal of physiology, pathophysiology and pharmacology
Shi Y,Li R,Yang J,Li X
33-9100 was used in Western Blotting to demonstrate that tight junction protein-1 cannot be used as a marker of tight junctions in a variety of cells.
Mon Sep 28 00:00:00 EDT 2020
Vitamin D Protects against Oxidative Stress and Inflammation in Human Retinal Cells.
Antioxidants (Basel, Switzerland)
Fernandez-Robredo P,González-Zamora J,Recalde S,Bilbao-Malavé V,Bezunartea J,Hernandez M,Garcia-Layana A
33-9100 was used in Western Blotting to suggest that vitamin D could protect the retina by enhancing antioxidant defense and through exhibiting anti-inflammatory properties.
Tue Sep 08 00:00:00 EDT 2020
Low-cost microphysiological systems: feasibility study of a tape-based barrier-on-chip for small intestine modeling.
Lab on a chip
Winkler TE,Feil M,Stronkman EFGJ,Matthiesen I,Herland A
33-9100 was used in Immunocytochemistry to present an approach to barrier-on-a-chip fabrication based on double-sided pressure-sensitive adhesive tape and off-the-shelf polycarbonate.
Tue Apr 07 00:00:00 EDT 2020
A tube-source X-ray microtomography approach for quantitative 3D microscopy of optically challenging cell-cultured samples.
Communications biology
Tamminen I,Lehto K,Hannula M,Ojansivu M,Johansson L,Kellomäki M,Miettinen S,Aula A,Ihalainen T,Hyttinen J
33-9100 was used in Immunocytochemistry to study optically challenging cell-cultured samples with microscopic 3D accuracy.
Fri Oct 02 00:00:00 EDT 2020
Gap Junctions between Endothelial Cells Are Disrupted by Circulating Extracellular Vesicles from Sickle Cell Patients with Acute Chest Syndrome.
International journal of molecular sciences
Gemel J,Mao Y,Lapping-Carr G,Beyer EC
33-9100 was used in Immunocytochemistry-immunoflourescence to discover how circulating extracellular vesicles from sickle cell patients with Acute Chest Syndrome can disrupt intercellular connections between endothelial cells.
Tue Nov 24 00:00:00 EST 2020
The intestinal quorum sensing 3-oxo-C12:2 Acyl homoserine lactone limits cytokine-induced tight junction disruption.
Tissue barriers
Aguanno D,Coquant G,Postal BG,Osinski C,Wieckowski M,Stockholm D,Grill JP,Carrière V,Seksik P,Thenet S
33-9100 was used in Immunocytochemistry-immunoflourescence to identify new actors involved in host-microbiota interplay in IBD, and study N-acyl homoserine lactones (AHL), molecules of the bacterial quorum sensing, which also impact the host.
Thu Oct 01 00:00:00 EDT 2020
Interplay of MPP5a with Rab11 synergistically builds epithelial apical polarity and zonula adherens.
Development (Cambridge, England)
Hao Y,Zhou Y,Yu Y,Zheng M,Weng K,Kou Z,Liang J,Zhang Q,Tang X,Xu P,Link BA,Yao K,Zou J
33-9100 was used in Immunohistochemistry to identify an unrecognized MPP5a-Rab11 complex and describe its essential role in guiding apical polarization and zonula adherens formation in epithelial cells.
Thu Nov 19 00:00:00 EST 2020
High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures.
eLife
Minn KT,Fu YC,He S,Dietmann S,George SC,Anastasio MA,Morris SA,Solnica-Krezel L
33-9100 was used in Immunocytochemistry to demonstrate that the gastruloid system models primate-specific features of embryogenesis, and that gastruloid cells exhibit evolutionarily conserved sorting behaviors.
Wed Nov 18 00:00:00 EST 2020
The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.
Nature communications
Liu Y,Zhang Y,Li T,Han J,Wang Y
33-9100 was used in Immunoprecipitation to provide a previously uncharacterized mechanistic insight into how feeding modulates the hepatic circadian clock.
Thu Jan 30 00:00:00 EST 2020
PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer.
Cell reports
Lin LL,Kost ER,Lin CL,Valente P,Wang CM,Kolonin MG,Daquinag AC,Tan X,Lucio N,Hung CN,Wang CP,Kirma NB,Huang TH
33-9100 was used in Mass cytometry to investigate the role of plasminogen activator inhibitor-1 signaling in rendering ineffective intercellular communication for the development of adiposity-associated endometrial cancer.
Tue Oct 13 00:00:00 EDT 2020
Whole-mount Immunohistochemistry of Adult Zebrafish Retina for Advanced Imaging.
Bio-protocol
Nagashima M,Hitchcock PF
33-9100 was used in Immunohistochemistry to describe an improved method of for retinal whole-mount preparations.
Sun Dec 20 00:00:00 EST 2020
Epigenomic and Transcriptomic Changes During Human RPE EMT in a Stem Cell Model of Epiretinal Membrane Pathogenesis and Prevention by Nicotinamide.
Stem cell reports
Boles NC,Fernandes M,Swigut T,Srinivasan R,Schiff L,Rada-Iglesias A,Wang Q,Saini JS,Kiehl T,Stern JH,Wysocka J,Blenkinsop TA,Temple S
33-9100 was used in Immunohistochemistry to find that the vitamin B derivative nicotinamide downregulates these key transcriptional changes, and inhibits and partially reverses RPE EMT, revealing potential therapeutic routes to benefit patients with ERM, macular pucker and PVR.
Tue Apr 14 00:00:00 EDT 2020
Epigenomic and Transcriptomic Changes During Human RPE EMT in a Stem Cell Model of Epiretinal Membrane Pathogenesis and Prevention by Nicotinamide.
Stem cell reports
Boles NC,Fernandes M,Swigut T,Srinivasan R,Schiff L,Rada-Iglesias A,Wang Q,Saini JS,Kiehl T,Stern JH,Wysocka J,Blenkinsop TA,Temple S
33-9100 was used in Immunohistochemistry to find that the vitamin B derivative nicotinamide downregulates these key transcriptional changes, and inhibits and partially reverses RPE EMT, revealing potential therapeutic routes to benefit patients with ERM, macular pucker and PVR.
Tue Apr 14 00:00:00 EDT 2020
Robotic fluidic coupling and interrogation of multiple vascularized organ chips.
Nature biomedical engineering
Novak R,Ingram M,Marquez S,Das D,Delahanty A,Herland A,Maoz BM,Jeanty SSF,Somayaji MR,Burt M,Calamari E,Chalkiadaki A,Cho A,Choe Y,Chou DB,Cronce M,Dauth S,Divic T,Fernandez-Alcon J,Ferrante T,Ferrier J,FitzGerald EA,Fleming R,Jalili-Firoozinezhad S,Grevesse T,Goss JA,Hamkins-Indik T,Henry O,Hinojosa C,Huffstater T,Jang KJ,Kujala V,Leng L,Mannix R,Milton Y,Nawroth J,Nestor BA,Ng CF,O'Connor B,Park TE,Sanchez H,Sliz J,Sontheimer-Phelps A,Swenor B,Thompson G,Touloumes GJ,Tranchemontagne Z,Wen N,Yadid M,Bahinski A,Hamilton GA,Levner D,Levy O,Przekwas A,Prantil-Baun R,Parker KK,Ingber DE
33-9100 was used in Immunocytochemistry-immunoflourescence to predict the distribution of an inulin tracer perfused through the multi-organ human-body-on-chips.
Wed Apr 01 00:00:00 EDT 2020
The Mammalian Crumbs Complex Defines a Distinct Polarity Domain Apical of Epithelial Tight Junctions.
Current biology : CB
Tan B,Yatim SMJM,Peng S,Gunaratne J,Hunziker W,Ludwig A
33-9100 was used in Western Blotting and Immunocytochemistry to study the architecture of the apical junctional complex in fully polarized MDCK-II cells.
Mon Jul 20 00:00:00 EDT 2020
The Mammalian Crumbs Complex Defines a Distinct Polarity Domain Apical of Epithelial Tight Junctions.
Current biology : CB
Tan B,Yatim SMJM,Peng S,Gunaratne J,Hunziker W,Ludwig A
33-9100 was used in Western Blotting and Immunocytochemistry to study the architecture of the apical junctional complex in fully polarized MDCK-II cells.
Mon Jul 20 00:00:00 EDT 2020
Dorsal-Ventral Differences in Retinal Structure in the Pigmented Royal College of Surgeons Model of Retinal Degeneration.
Frontiers in cellular neuroscience
Greferath U,Huynh M,Jobling AI,Vessey KA,Venables G,Surrao D,O'Neill HC,Limnios IJ,Fletcher EL
33-9100 was used in Immunohistochemistry to model sectorial retinitis pigmentosa, a disease known to predominantly effect the inferior retina.
Sat Feb 06 00:00:00 EST 2021
Phase Separation of Zonula Occludens Proteins Drives Formation of Tight Junctions.
Cell
Beutel O,Maraspini R,Pombo-García K,Martin-Lemaitre C,Honigmann A
33-9100 was used in Western Blotting to understand how zona occludens (ZO) proteins organize junction assembly.
Thu Oct 31 00:00:00 EDT 2019
A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles.
Cell stem cell
Zhang JZ,Termglinchan V,Shao NY,Itzhaki I,Liu C,Ma N,Tian L,Wang VY,Chang ACY,Guo H,Kitani T,Wu H,Lam CK,Kodo K,Sayed N,Blau HM,Wu JC
33-9100 was used in Immunocytochemistry-immunoflourescence to study the effects of hiPSC TBX5Clover2 and NKX2-5TagRFP double reporters in their ability to delineate cardiac lineages and isolate lineage-specific subpopulations.
Thu May 02 00:00:00 EDT 2019
Fibronectin inhibitor pUR4 attenuates tumor necrosis factor α-induced endothelial hyperpermeability by modulating β1 integrin activation.
Journal of biomedical science
Lee TH,Hsieh ST,Chiang HY
33-9100 was used in Immunocytochemistry-immunoflourescence to investigate whether the FN inhibitor pUR4 prevents FN deposition into the subendothelial matrix and attenuates endothelial leakage.
Thu May 16 00:00:00 EDT 2019
Graft immaturity and safety concerns in transplanted human kidney organoids.
Experimental & molecular medicine
Nam SA,Seo E,Kim JW,Kim HW,Kim HL,Kim K,Kim TM,Ju JH,Gomez IG,Uchimura K,Humphreys BD,Yang CW,Lee JY,Kim J,Cho DW,Freedman BS,Kim YK
33-9100 was used in Immunohistochemistry to suggest that kidney organoids derived from iPS cells may be transplantable but strategies to improve nephron differentiation and purity are required before they can be applied in humans as a therapeutic option.
Thu Nov 28 00:00:00 EST 2019
Faecal Proteases from Pouchitis Patients Activate Protease Activating Receptor-2 to Disrupt the Epithelial Barrier.
Journal of Crohn's & colitis
Hoffman S,Aviv Cohen N,Carroll IM,Tulchinsky H,Borovok I,Dotan I,Maharshak N
33-9100 was used in Western Blotting to study the relationship between faecal proteolytic activity and protease activating receptor activation in epithelial barrier dysfunction and determine the source of proteases.
Tue Dec 10 00:00:00 EST 2019
Butyrate Does Not Protect Against Inflammation-induced Loss of Epithelial Barrier Function and Cytokine Production in Primary Cell Monolayers From Patients With Ulcerative Colitis.
Journal of Crohn's & colitis
Vancamelbeke M,Laeremans T,Vanhove W,Arnauts K,Ramalho AS,Farré R,Cleynen I,Ferrante M,Vermeire S
33-9100 was used in Immunohistochemistry-immunofluorescence to study the effect of butyrate on epithelial barrier function in patients with ulcerative colitis.
Fri Sep 27 00:00:00 EDT 2019
Regulation of the apical extension morphogenesis tunes the mechanosensory response of microvilliated neurons.
PLoS biology
Desban L,Prendergast A,Roussel J,Rosello M,Geny D,Wyart C,Bardet PL
33-9100 was used in Immunohistochemistry-immunofluorescence to study the morphogenesis and function of sensory microvilliated apical extensions, focusing on cerebrospinal fluid-contacting neurons.
Mon Apr 01 00:00:00 EDT 2019
SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.
The Journal of cell biology
Awadia S,Huq F,Arnold TR,Goicoechea SM,Sun YJ,Hou T,Kreider-Letterman G,Massimi P,Banks L,Fuentes EJ,Miller AL,Garcia-Mata R
33-9100 was used in Immunocytochemistry-immunoflourescence to show that SGEF forms a ternary complex with Scribble and Dlg1, two members of the Scribble complex.
Mon Aug 05 00:00:00 EDT 2019
SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.
The Journal of cell biology
Awadia S,Huq F,Arnold TR,Goicoechea SM,Sun YJ,Hou T,Kreider-Letterman G,Massimi P,Banks L,Fuentes EJ,Miller AL,Garcia-Mata R
33-9100 was used in Immunocytochemistry-immunoflourescence to show that SGEF forms a ternary complex with Scribble and Dlg1, two members of the Scribble complex.
Mon Aug 05 00:00:00 EDT 2019
Chemical cocktails enable hepatic reprogramming of human urine-derived cells with a single transcription factor.
Acta pharmacologica Sinica
Tang W,Guo R,Shen SJ,Zheng Y,Lu YT,Jiang MM,Cui X,Jiang CZ,Xie X
33-9100 was used in Immunocytochemistry-immunoflourescence to provides a strategy to generate functional hepatocyte-like cells from hUCs by using a single TF plus a chemical cocktail.
Wed May 01 00:00:00 EDT 2019
The transmembrane protein Crb2a regulates cardiomyocyte apicobasal polarity and adhesion in zebrafish.
Development (Cambridge, England)
Jiménez-Amilburu V,Stainier DYR
33-9100 was used in Immunohistochemistry to show that blood flow and Nrg/ErbB2 signaling regulate Crb2a localization dynamics, and that that Crb2a regulates cardiac trabeculation by controlling the localization of tight and adherens junction proteins in cardiomyocytes.
Tue May 07 00:00:00 EDT 2019
Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ding W,Wu Q,Sun L,Pan NC,Wang X
33-9100 was used in Immunohistochemistry (PFA fixed) to provide insights into how ciliogenesis plays roles in cortical development and how primary microcephaly is induced by Cenpj mutations in humans.
Wed Mar 13 00:00:00 EDT 2019
Elfn1-Induced Constitutive Activation of mGluR7 Determines Frequency-Dependent Recruitment of Somatostatin Interneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Stachniak TJ,Sylwestrak EL,Scheiffele P,Hall BJ,Ghosh A
33-9100 was used in Immunocytochemistry to conclude that layer-specific synaptic properties onto somatostatin interneurons are mediated by both constitutive mGluR7 recruitment and regulated GluK2 kainate receptor recruitment, revealing a mechanism that generates diversity in physiological responses of interneurons.
Wed Jun 05 00:00:00 EDT 2019
Generation and Characterization of Induced Pluripotent Stem Cells and Retinal Organoids From a Leber's Congenital Amaurosis Patient With Novel RPE65 Mutations.
Frontiers in molecular neuroscience
Li G,Gao G,Wang P,Song X,Xu P,Xie B,Zhou T,Pan G,Peng F,Zhang Q,Ge J,Zhong X
33-9100 was used in Immunocytochemistry-immunoflourescence to provide the patient specific, disease targeted retinal organoids containing photoreceptor and RPE cells to facilitate the study of personalized pathogenic mechanisms of disease, drug screening, and cell replacement therapy.
Thu Oct 01 00:00:00 EDT 2020
Silver nanoparticle-induced expression of proteins related to oxidative stress and neurodegeneration in an in vitro human blood-brain barrier model.
Nanotoxicology
Khan AM,Korzeniowska B,Gorshkov V,Tahir M,Schrøder H,Skytte L,Rasmussen KL,Khandige S,Møller-Jensen J,Kjeldsen F
33-9100 was used in Immunocytochemistry-immunoflourescence to provide detailed insight into the toxic potency of AgNPs on in vitro BBB model and adds to the understanding of the adaptive role of BBB with regards to AgNPs-mediated toxicity.
Fri Mar 01 00:00:00 EST 2019
miR-24 Is Elevated in Ulcerative Colitis Patients and Regulates Intestinal Epithelial Barrier Function.
The American journal of pathology
Soroosh A,Rankin CR,Polytarchou C,Lokhandwala ZA,Patel A,Chang L,Pothoulakis C,Iliopoulos D,Padua DM
33-9100 was used in Immunohistochemistry to discover upon study of patients with ulcerative colitis, miR-24 was elevated in intestinal epithelial cells and regulates the cell barrier function.
Sun Sep 01 00:00:00 EDT 2019
Pharmacological stimulation of G-protein coupled receptor 40 alleviates cytokine-induced epithelial barrier disruption in airway epithelial Calu-3 cells.
International immunopharmacology
Moonwiriyakit A,Koval M,Muanprasat C
33-9100 was used in Immunocytochemistry to investigate the effect of GPR40 stimulation on proinflammatory cytokine (TNFα and IL-1β)-induced tight junction disruption in human airway epithelial Calu-3 cells using GW9508, a GPR40 agonist.
Thu Aug 01 00:00:00 EDT 2019
The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity.
Journal of cell science
Elbediwy A,Zhang Y,Cobbaut M,Riou P,Tan RS,Roberts SK,Tynan C,George R,Kjaer S,Martin-Fernandez ML,Thompson BJ,McDonald NQ,Parker PJ
33-9100 was used in Immunocytochemistry to conclude that this aPKCι-FARP2 complex formation acts as a positive feedback control to drive polarisation through aPKCι and other Cdc42 effectors.
Thu Apr 25 00:00:00 EDT 2019
Hypoxic Environment Promotes Barrier Formation in Human Intestinal Epithelial Cells through Regulation of MicroRNA 320a Expression.
Molecular and cellular biology
Muenchau S,Deutsch R,de Castro IJ,Hielscher T,Heber N,Niesler B,Lusic M,Stanifer ML,Boulant S
33-9100 was used in Immunocytochemistry-immunoflourescence to evaluate the mechanisms by which low oxygen conditions impact the barrier function of human IECs.
Mon Jul 15 00:00:00 EDT 2019
3D in vitro model for human corneal endothelial cell maturation.
Experimental eye research
Hutcheon AEK,Zieske JD,Guo X
33-9100 was used in Immunocytochemistry to examine the feasibility of utilizing a 3-dimensional corneal stromal construct, which consists of human corneal fibroblasts and their self-assembled matrix, to observe the development and maturation of human corneal endothelial cells in a co-culture model.
Mon Jul 01 00:00:00 EDT 2019
Acute effects of hyperglycemia on the peripheral nervous system in zebrafish ( Danio rerio) following nitroreductase-mediated β-cell ablation.
American journal of physiology. Regulatory, integrative and comparative physiology
Rocker A,Howell J,Voithofer G,Clark JK
33-9100 was used in Immunohistochemistry to provide a novel model of acute diabetic peripheral neuropathy (DPN) in zebrafish ( Danio rerio) larvae.
Mon Apr 01 00:00:00 EDT 2019
Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate.
Developmental biology
Liberti DC,Zepp JA,Bartoni CA,Liberti KH,Zhou S,Lu M,Morley MP,Morrisey EE
33-9100 was used in Immunohistochemistry to demonstrate that DNA methyltransferase 1 (Dnmt1) is required for early branching morphogenesis of the lungs and for restraining epithelial fate specification.
Tue Oct 15 00:00:00 EDT 2019
Disruption of peripheral nerve development in a zebrafish model of hyperglycemia.
Journal of neurophysiology
Ennerfelt H,Voithofer G,Tibbo M,Miller D,Warfield R,Allen S,Kennett Clark J
33-9100 was used in Immunohistochemistry to present a novel zebrafish model that mimics diabetic peripheral neuropathy where the integrity of the peripheral nerve is dysregulated following the induction of hyperglycemia.
Thu Aug 01 00:00:00 EDT 2019
penner/lgl2 is required for the integrity of the photoreceptor layer in the zebrafish retina.
Biology open
Kujawski S,Sonawane M,Knust E
33-9100 was used in Immunohistochemistry-immunofluorescence to determine the role of Lgl2 in the development of the zebrafish retina.
Tue Apr 23 00:00:00 EDT 2019
Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis.
Redox biology
Cremonini E,Daveri E,Mastaloudis A,Adamo AM,Mills D,Kalanetra K,Hester SN,Wood SM,Fraga CG,Oteiza PI
33-9100 was used in Western Blotting to investigate if benefits of previous supplementation is related to anthocyanins capacity to sustain intestinal monolayer integrity and HFD-associated dysbiosis.
Sun Sep 01 00:00:00 EDT 2019
Characterization of an immortalized human small airway basal stem/progenitor cell line with airway region-specific differentiation capacity.
Respiratory research
Wang G,Lou HH,Salit J,Leopold PL,Driscoll S,Schymeinsky J,Quast K,Visvanathan S,Fine JS,Thomas MJ,Crystal RG
33-9100 was used in Immunocytochemistry-immunoflourescence to generate and characterise an immortalized human small airway basal cell line.
Fri Aug 23 00:00:00 EDT 2019
Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications.
Cell stem cell
Vatine GD,Barrile R,Workman MJ,Sances S,Barriga BK,Rahnama M,Barthakur S,Kasendra M,Lucchesi C,Kerns J,Wen N,Spivia WR,Chen Z,Van Eyk J,Svendsen CN
33-9100 was used in Immunocytochemistry-immunoflourescence to create a neurovascular unit that recapitulates complex BBB functions.
Thu Jun 06 00:00:00 EDT 2019
Epithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility.
Life science alliance
Søgaard PP,Ito N,Sato N,Fujita Y,Matter K,Itoh Y
33-9100 was used in Immunohistochemistry to study the molecular mechanisms that allow epithelial cells to establish polarity.
Fri Feb 01 00:00:00 EST 2019
The Human Upper Respiratory Tract Epithelium Is Susceptible to Flaviviruses.
Frontiers in microbiology
Vielle NJ,García-Nicolás O,Oliveira Esteves BI,Brügger M,Summerfield A,Alves MP
33-9100 was used in Immunocytochemistry to suggest that the human upper respiratory tract epithelium is a target for flaviviruses and could potentially play a role in the spread of infection to other body compartments through basolateral virus release.
Wed Sep 30 00:00:00 EDT 2020
Autophagy Protects the Blood-Brain Barrier Through Regulating the Dynamic of Claudin-5 in Short-Term Starvation.
Frontiers in physiology
Yang Z,Huang C,Wu Y,Chen B,Zhang W,Zhang J
33-9100 was used in Immunohistochemistry to study the essential role of autophagy in maintaining the integrity of endothelial barrier by regulating the localisation of Claudin-5 under starvation.
Thu Oct 01 00:00:00 EDT 2020
Controlling Epithelial Polarity: A Human Enteroid Model for Host-Pathogen Interactions.
Cell reports
Co JY,Margalef-Català M,Li X,Mah AT,Kuo CJ,Monack DM,Amieva MR
33-9100 was used in Immunocytochemistry-immunoflourescence to develop a technique to reverse enteroid polarity in Human enteroids-epithelial spheroids so the apical surface everts to face the media.
Tue Feb 26 00:00:00 EST 2019
CLIC4 regulates late endosomal trafficking and matrix degradation activity of MMP14 at focal adhesions in RPE cells.
Scientific reports
Hsu KS,Otsu W,Li Y,Wang HC,Chen S,Tsang SH,Chuang JZ,Sung CH
33-9100 was used in Western Blotting to demonstrate that CLIC4 is a novel matrix microenvironment modulator and a novel regulator for late endosomal cargo sorting. Moreover, the late endosomal sorting of MMP14 actively regulates its surface activation in RPE cells.
Thu Aug 22 00:00:00 EDT 2019
Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function.
Nature communications
Dumm RE,Fiege JK,Waring BM,Kuo CT,Langlois RA,Heaton NS
33-9100 was used in Immunocytochemistry to determine if any cells can survive direct influenza B virus infection.
Fri Feb 15 00:00:00 EST 2019
Transforming growth factor β (TGFβ) induces NUAK kinase expression to fine-tune its signaling output.
The Journal of biological chemistry
Kolliopoulos C,Raja E,Razmara M,Heldin P,Heldin CH,Moustakas A,van der Heide LP
33-9100 was used in Immunocytochemistry-immunoflourescence to identify a bifurcating loop during TGFΒ signalling, through transcriptional induction of NUAK1.
Fri Mar 15 00:00:00 EDT 2019
Fabricating retinal pigment epithelial cell sheets derived from human induced pluripotent stem cells in an automated closed culture system for regenerative medicine.
PloS one
Matsumoto E,Koide N,Hanzawa H,Kiyama M,Ohta M,Kuwabara J,Takeda S,Takahashi M
33-9100 was used in Immunohistochemistry to culture retinal pigment epithelium cell sheets in an automated closed culture system for regenerative medicine.
Mon Nov 25 00:00:00 EST 2019
Role of Endoplasmic Reticulum Stress-Autophagy Axis in Severe Burn-Induced Intestinal Tight Junction Barrier Dysfunction in Mice.
Frontiers in physiology
Huang Y,Wang Y,Feng Y,Wang P,He X,Ren H,Wang F
33-9100 was used in Western Blotting to suggest that the ER stress-autophagy axis contributes to the intestinal epithelial TJ barrier dysfunction after severe burn injury.
Wed Sep 30 00:00:00 EDT 2020
A collagen IV-derived peptide disrupts α5β1 integrin and potentiates Ang2/Tie2 signaling.
JCI insight
Mirando AC,Shen J,Silva RLE,Chu Z,Sass NC,Lorenc VE,Green JJ,Campochiaro PA,Popel AS,Pandey NB
33-9100 was used in Immunocytochemistry-immunoflourescence to study the mechanism by which the interactions between Tie2 and α5Β1 integrin maintain vascular homeostasis.
Thu Feb 21 00:00:00 EST 2019
Temporal Effects of Quercetin on Tight Junction Barrier Properties and Claudin Expression and Localization in MDCK II Cells.
International journal of molecular sciences
Gamero-Estevez E,Andonian S,Jean-Claude B,Gupta I,Ryan AK
33-9100 was used in Western Blotting to investigate the effect of quercetin on claudin expression and localisation in MDCK II cells, a cation-selective cell line, derived from the proximal tubule.
Wed Oct 02 00:00:00 EDT 2019
Temporal Effects of Quercetin on Tight Junction Barrier Properties and Claudin Expression and Localization in MDCK II Cells.
International journal of molecular sciences
Gamero-Estevez E,Andonian S,Jean-Claude B,Gupta I,Ryan AK
33-9100 was used in Western Blotting to investigate the effect of quercetin on claudin expression and localisation in MDCK II cells, a cation-selective cell line, derived from the proximal tubule.
Wed Oct 02 00:00:00 EDT 2019
PCP and Wnt pathway components act in parallel during zebrafish mechanosensory hair cell orientation.
Nature communications
Navajas Acedo J,Voas MG,Alexander R,Woolley T,Unruh JR,Li H,Moens C,Piotrowski T
33-9100 was used in Immunohistochemistry to show the orientation of mechanosensory hair cells in Zebrafish is established by parallel PCP and Wnt pathways.
Thu Sep 05 00:00:00 EDT 2019
Mouse embryo geometry drives formation of robust signaling gradients through receptor localization.
Nature communications
Zhang Z,Zwick S,Loew E,Grimley JS,Ramanathan S
33-9100 was used in Immunocytochemistry to demonstrate the importance of receptor localization and embryo geometry in shaping morphogen signaling during embryogenesis.
Fri Oct 04 00:00:00 EDT 2019
Sodium channels enable fast electrical signaling and regulate phagocytosis in the retinal pigment epithelium.
BMC biology
Johansson JK,Karema-Jokinen VI,Hakanen S,Jylhä A,Uusitalo H,Vihinen-Ranta M,Skottman H,Ihalainen TO,Nymark S
33-9100 was used in Immunohistochemistry to show that Nav channels are present in RPE, giving this tissue the capacity of fast electrical signaling.
Thu Aug 15 00:00:00 EDT 2019
Transcription factor TFAP2B up-regulates human corneal endothelial cell-specific genes during corneal development and maintenance.
The Journal of biological chemistry
Hara S,Kawasaki S,Yoshihara M,Winegarner A,Busch C,Tsujikawa M,Nishida K
33-9100 was used in Immunohistochemistry to study activating enhancer-binding protein 2 (TFAP2, AP-2), a neural crest-expressed transcription factor. It was found that within the AP-2 family, the TFAP2B gene is the only one expressed in human CECs in vivo and that its expression is strongly localized to the peripheral region of the corneal endothelium.
Fri Feb 15 00:00:00 EST 2019
Anti-H7N9 avian influenza A virus activity of interferon in pseudostratified human airway epithelium cell cultures.
Virology journal
Chen AJ,Dong J,Yuan XH,Bo H,Li SZ,Wang C,Duan ZJ,Zheng LS
33-9100 was used in Immunohistochemistry to study H7N9 avian influenza A virus replication kinetics and anti-H7N9 effect of recombinant human α2b and rhIFN-λ1 in different cell lines.
Wed Apr 03 00:00:00 EDT 2019
A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation.
Nature communications
Thestrup MI,Caviglia S,Cayuso J,Heyne RLS,Ahmad R,Hofmeister W,Satriano L,Wilkinson DG,Andersen JB,Ober EA
33-9100 was used in Immunohistochemistry to characterize hepatopancreatic ductal (HPD) system morphogenesis by high-resolution microscopy in zebrafish.
Tue Nov 19 00:00:00 EST 2019
Blood Flow Suppresses Vascular Anomalies in a Zebrafish Model of Cerebral Cavernous Malformations.
Circulation research
Rödel CJ,Otten C,Donat S,Lourenço M,Fischer D,Kuropka B,Paolini A,Freund C,Abdelilah-Seyfried S
33-9100 was used in Immunohistochemistry to identify blood flow as an important physiological factor that is protective in the cause of this devastating vascular pathology.
Fri Oct 25 00:00:00 EDT 2019
Focal adhesions are essential to drive zebrafish heart valve morphogenesis.
The Journal of cell biology
Gunawan F,Gentile A,Fukuda R,Tsedeke AT,Jiménez-Amilburu V,Ramadass R,Iida A,Sehara-Fujisawa A,Stainier DYR
33-9100 was used in Immunohistochemistry to show that FA signaling mediated by Integrin α5β1 and Talin1 promotes AV EC migration and overall shaping of the valve leaflets.
Mon Mar 04 00:00:00 EST 2019
Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells.
Scientific reports
Maruhashi R,Eguchi H,Akizuki R,Hamada S,Furuta T,Matsunaga T,Endo S,Ichihara K,Ikari A
33-9100 was used in Immunocytochemistry to suggest that chrysin may be useful as an adjuvant chemotherapy in lung SCC.
Tue Sep 24 00:00:00 EDT 2019
A Cleared View on Retinal Organoids.
Cells
Cora V,Haderspeck J,Antkowiak L,Mattheus U,Neckel PH,Mack AF,Bolz S,Ueffing M,Pashkovskaia N,Achberger K,Liebau S
33-9100 was used in Immunocytochemistry to visualize the interconnection points of photoreceptor and bipolar cells forming the retinal-specific ribbon synapses.
Sun Apr 28 00:00:00 EDT 2019
Mesencephalic origin of the inferior lobe in zebrafish.
BMC biology
Bloch S,Thomas M,Colin I,Galant S,Machado E,Affaticati P,Jenett A,Yamamoto K
33-9100 was used in Immunohistochemistry-immunofluorescence to study the development of the inferior lobe in zebrafish.
Fri Mar 08 00:00:00 EST 2019
Perinatal hormones favor CC17 group B Streptococcus intestinal translocation through M cells and hypervirulence in neonates.
eLife
Hays C,Touak G,Bouaboud A,Fouet A,Guignot J,Poyart C,Tazi A
33-9100 was used in Immunohistochemistry to study the impact of estradiol (E2) and progesterone (P4), which impregnate the fetus during pregnancy, on GBS neonatal infection in cellular and mouse models of hormonal exposure corresponding to concentrations found at birth (E2-P4 C0) and over 7 days old (E2-P4 C7).
Mon Nov 11 00:00:00 EST 2019
Parental centrioles are dispensable for deuterosome formation and function during basal body amplification.
EMBO reports
Zhao H,Chen Q,Fang C,Huang Q,Zhou J,Yan X,Zhu X
33-9100 was used in Immunocytochemistry to show that both parental centrioles are dispensable for deuterosome formation and deuterosomes can be assembled autonomously to mediate de novo centriole amplification in multiciliated cells.
Mon Apr 01 00:00:00 EDT 2019
Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
Nature
Meisel M,Hinterleitner R,Pacis A,Chen L,Earley ZM,Mayassi T,Pierre JF,Ernest JD,Galipeau HJ,Thuille N,Bouziat R,Buscarlet M,Ringus DL,Wang Y,Li Y,Dinh V,Kim SM,McDonald BD,Zurenski MA,Musch MW,Furtado GC,Lira SA,Baier G,Chang EB,Eren AM,Weber CR,Busque L,Godley LA,Verdú EF,Barreiro LB,Jabri B
33-9100 was used in Immunofluorescence in immunohistochemistry on frozen tissues to study the role played by bacterial translocation and increased interleukin-6 production in the development of pre-leukaemic myeloproliferation.
Tue May 01 00:00:00 EDT 2018
Expanding Actin Rings Zipper the Mouse Embryo for Blastocyst Formation.
Cell
Zenker J,White MD,Gasnier M,Alvarez YD,Lim HYG,Bissiere S,Biro M,Plachta N
33-9100 was used in Immunohistochemistry to study using live imaging of mouse embryos to reveal an actin-zippering mechanism driving this embryo sealing.
Thu Apr 19 00:00:00 EDT 2018
Biopsy-derived Intestinal Epithelial Cell Cultures for Pathway-based Stratification of Patients With Inflammatory Bowel Disease.
Journal of Crohn's & colitis
Vanhove W,Nys K,Arijs I,Cleynen I,Noben M,De Schepper S,Van Assche G,Ferrante M,Vermeire S
33-9100 was used in Immunocytochemistry to identify and quantify epithelial endoplasmic reticulum stress in a patient-specific manner in an attempt towards personalised therapy in inflammatory bowel disease.
Wed Jan 24 00:00:00 EST 2018
Elasticity-based boosting of neuroepithelial nucleokinesis via indirect energy transfer from mother to daughter.
PLoS biology
Shinoda T,Nagasaka A,Inoue Y,Higuchi R,Minami Y,Kato K,Suzuki M,Kondo T,Kawaue T,Saito K,Ueno N,Fukazawa Y,Nagayama M,Miura T,Adachi T,Miyata T
33-9100 was used in Immunohistochemistry to study how heterogenous interkinetic nuclear migrations are collectively coordinated in neural progenitor cells.
Sun Apr 01 00:00:00 EDT 2018
Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.
Cellular and molecular gastroenterology and hepatology
Workman MJ,Gleeson JP,Troisi EJ,Estrada HQ,Kerns SJ,Hinojosa CD,Hamilton GA,Targan SR,Svendsen CN,Barrett RJ
33-9100 was used in Immunohistochemistry to combine human intestinal organoids (generated from induced pluripotent stem cells) with microengineering technology to develop the Intestine-Chip, a suitable platform for the enhanced study of gastrointestinal conditions.
Mon Mar 21 00:00:00 EDT 2022
Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.
Cellular and molecular gastroenterology and hepatology
Workman MJ,Gleeson JP,Troisi EJ,Estrada HQ,Kerns SJ,Hinojosa CD,Hamilton GA,Targan SR,Svendsen CN,Barrett RJ
33-9100 was used in Immunohistochemistry to combine human intestinal organoids (generated from induced pluripotent stem cells) with microengineering technology to develop the Intestine-Chip, a suitable platform for the enhanced study of gastrointestinal conditions.
Mon Mar 21 00:00:00 EDT 2022
A novel high-throughput assay for respiration in isolated brain microvessels reveals impaired mitochondrial function in the aged mice.
GeroScience
Sure VN,Sakamuri SSVP,Sperling JA,Evans WR,Merdzo I,Mostany R,Murfee WL,Busija DW,Katakam PVG
33-9100 was used in Immunohistochemistry-immunofluorescence to develop a novel method to measure mitochondrial respiratory parameters in freshly isolated microvessels from mouse brain ex vivo.
Wed Aug 01 00:00:00 EDT 2018
Endocytic trafficking factor VPS45 is essential for spatial regulation of lens fiber differentiation in zebrafish.
Development (Cambridge, England)
Mochizuki T,Kojima Y,Nishiwaki Y,Harakuni T,Masai I
33-9100 was used in Immunohistochemistry to study a novel role of endosome trafficking to ensure equator-dependent commencement of lens fibre differentiation.
Mon Oct 15 00:00:00 EDT 2018
Cxcl12a induces snail1b expression to initiate collective migration and sequential Fgf-dependent neuromast formation in the zebrafish posterior lateral line primordium.
Development (Cambridge, England)
Neelathi UM,Dalle Nogare D,Chitnis AB
33-9100 was used in Immunohistochemistry to reveal an unexpected link between the initiation of collective migration and sequential formation of protoneuromasts in the primordium.
Mon Jul 30 00:00:00 EDT 2018
Influenza A Virus M2 Protein Apical Targeting Is Required for Efficient Virus Replication.
Journal of virology
Wohlgemuth N,Lane AP,Pekosz A
33-9100 was used in Immunocytochemistry-immunoflourescence to determine the role of M2 protein apical targeting in influenza A virus replication.
Thu Nov 15 00:00:00 EST 2018
Hamartoma-like lesions in the mouse retina: an animal model of Pten hamartoma tumour syndrome.
Disease models & mechanisms
Tachibana N,Touahri Y,Dixit R,David LA,Adnani L,Cantrup R,Aavani T,Wong RO,Logan C,Kurek KC,Schuurmans C
33-9100 was used in Immunohistochemistry to develop a novel PTEN hamartoma tumour syndrome mouse model that reproducibly forms hamartoma-like lesion in the central retina by postnatal day 21.
Mon May 21 00:00:00 EDT 2018
BAMBI is a novel HIF1-dependent modulator of TGFβ-mediated disruption of cell polarity during hypoxia.
Journal of cell science
Raykhel I,Moafi F,Myllymäki SM,Greciano PG,Matlin KS,Moyano JV,Manninen A,Myllyharju J
33-9100 was used in Immunocytochemistry to report that hypoxia disrupts polarised epithelial morphogenesis of MDCK cells in a Hypoxia-inducible factor 1(HIF1)α-dependent manner by modulating the transforming growth factor-Β signalling pathway.
Wed May 23 00:00:00 EDT 2018
Tight junctions negatively regulate mechanical forces applied to adherens junctions in vertebrate epithelial tissue.
Journal of cell science
Hatte G,Prigent C,Tassan JP
33-9100 was used in Immunohistochemistry-immunofluorescence to examine the role of tight junctions during cytokinesis in the epithelium of the Xenopus laevis embryo.
Mon Feb 05 00:00:00 EST 2018
Tight junctions negatively regulate mechanical forces applied to adherens junctions in vertebrate epithelial tissue.
Journal of cell science
Hatte G,Prigent C,Tassan JP
33-9100 was used in Immunohistochemistry-immunofluorescence to examine the role of tight junctions during cytokinesis in the epithelium of the Xenopus laevis embryo.
Mon Feb 05 00:00:00 EST 2018
Cell injury triggers actin polymerization to initiate epithelial restitution.
Journal of cell science
Aihara E,Medina-Candelaria NM,Hanyu H,Matthis AL,Engevik KA,Gurniak CB,Witke W,Turner JR,Zhang T,Montrose MH
33-9100 was used in Immunohistochemistry-immunofluorescence to show initial actin polymerization occurs in the lateral membrane, and is primarily important to initiate dead cell exfoliation and cell migration to close the gap.
Mon Aug 20 00:00:00 EDT 2018
Tension-dependent regulation of mammalian Hippo signaling through LIMD1.
Journal of cell science
Ibar C,Kirichenko E,Keepers B,Enners E,Fleisch K,Irvine KD
33-9100 was used in Immunocytochemistry-immunoflourescence to study the tension-dependent regulation of mammalian Hippo signalling through LIMD1.
Fri Mar 02 00:00:00 EST 2018
Calcium signaling mediates five types of cell morphological changes to form neural rosettes.
Journal of cell science
Hříbková H,Grabiec M,Klemová D,Slaninová I,Sun YM
33-9100 was used in Immunocytochemistry to demonstrate that the dismantlement of neural rosettes, mediated by the destruction of cytoskeletal elements, promotes neurogenesis and astrogenesis prematurely, indicating that an intact rosette structure is essential for orderly neural development.
Mon Feb 12 00:00:00 EST 2018
Generation of Retinal Organoids with Mature Rods and Cones from Urine-Derived Human Induced Pluripotent Stem Cells.
Stem cells international
Li G,Xie B,He L,Zhou T,Gao G,Liu S,Pan G,Ge J,Peng F,Zhong X
33-9100 was used in Immunohistochemistry to study the ability of urine cells that have been reprogrammed into human induced pluripotent stem cells to differentiate towards retinal fates and form 3D retinal organoids.
Thu Oct 01 00:00:00 EDT 2020
Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment.
American journal of physiology. Heart and circulatory physiology
Van Skike CE,Jahrling JB,Olson AB,Sayre NL,Hussong SA,Ungvari Z,Lechleiter JD,Galvan V
33-9100 was used in Western Blotting to study the role of mammalian/mechanistic target of rapamycin as a critical mediator of blood-brain barrier breakdown in models of Alzheimer's disease and vascular cognitive impairment.
Sun Apr 01 00:00:00 EDT 2018
Effects of Chemical Chaperones on Thyroid Hormone Transport by MCT8 Mutants in Patient-Derived Fibroblasts.
Endocrinology
Groeneweg S,van den Berge A,Meima ME,Peeters RP,Visser TJ,Visser WE
33-9100 was used in Immunocytochemistry to study the effectiveness of chemical chaperones in the restoration of thyroid hormone signaling in MCT8 mutant patient-derived fibroblasts, highlighting a disparity in the potency of chaperones amongst different cell types.
Thu Mar 01 00:00:00 EST 2018
MEF2 transcription factors in human placenta and involvement in cytotrophoblast invasion and differentiation.
Physiological genomics
Li L,Rubin LP,Gong X
33-9100 was used in Western Blotting to show that members of the MEF2 family are differentially expressed in human placental cytotrophoblasts, with MEF2B and MEF2D being highly expressed in first trimester extravillous cytotrophoblasts.
Mon Jan 01 00:00:00 EST 2018
The downregulation of WWOX induces epithelial-mesenchymal transition and enhances stemness and chemoresistance in breast cancer.
Experimental biology and medicine (Maywood, N.J.)
Li J,Liu J,Li P,Zhou C,Liu P
33-9100 was used in Immunocytochemistry-immunoflourescence to study the role of WW domain-containing oxidoreductase in the chemoresistance of breast cancer through the regulation of cell stemness and epithelial-mesenchymal transition.
Sat Sep 01 00:00:00 EDT 2018
Vitamin D ameliorates neonatal necrotizing enterocolitis via suppressing TLR4 in a murine model.
Pediatric research
Shi Y,Liu T,Zhao X,Yao L,Hou A,Fu J,Xue X
33-9100 was used in Western Blotting to determine whether the vitamin D/vitamin D receptor pathway ameliorates necrotizing enterocolitis by regulating TLR4.
Tue May 01 00:00:00 EDT 2018
Pregnane X Receptor Deletion Modifies Recognition Memory and Electroencephalographic Activity.
Neuroscience
Boussadia B,Lakhal L,Payrastre L,Ghosh C,Pascussi JM,Gangarossa G,Marchi N
33-9100 was used in Western Blotting to link modulation of nuclear receptors in the physiology and pathophysiology of the brain and central nervous system.
Thu Feb 01 00:00:00 EST 2018
The endocochlear potential as an indicator of reticular lamina integrity after noise exposure in mice.
Hearing research
Ohlemiller KK,Kaur T,Warchol ME,Withnell RH
33-9100 was used in Immunohistochemistry-immunofluorescence to find that the exposure level-versus-acute EP relation is strain-dependent, with B6 mice widely diverging from both CBA and BALB.
Sun Apr 01 00:00:00 EDT 2018
Polarity and morphogenesis of the eye epithelium requires the adhesion junction associated adaptor protein Traf4.
Cell adhesion & migration
Hehr CL,Halabi R,McFarlane S
33-9100 was used in Immunohistochemistry to model how Traf4a regulates apical junction plasticity in nascent eye epithelium, allowing for its polarization and morphogenesis.
Fri Mar 06 00:00:00 EST 2020
Differential effects of depot formulations of GnRH agonist leuprorelin and antagonist degarelix on the seminiferous epithelium of the rat testis.
Biomedical research (Tokyo, Japan)
Hori JI,Koga D,Kakizaki H,Watanabe T
33-9100 was used in Immunocytochemistry-immunoflourescence to clarify the underlying differences in the effects of GnRH agonists and antagonists on spermatogenesis.
Thu Nov 08 00:00:00 EST 2018
A 3D intestinal tissue model supports Clostridioides difficile germination, colonization, toxin production and epithelial damage.
Anaerobe
Shaban L,Chen Y,Fasciano AC,Lin Y,Kaplan DL,Kumamoto CA,Mecsas J
33-9100 was used in Immunocytochemistry-immunoflourescence to compare the ability of Clostridioides difficile spores to germinate, produce toxin and cause tissue damage in a bioengineered 3D tissue model versus in a 2D transwell model in which human cells form a polarised monolayer.
Sun Apr 01 00:00:00 EDT 2018
Feeder-free differentiation of cells exhibiting characteristics of corneal endothelium from human induced pluripotent stem cells.
Biology open
Wagoner MD,Bohrer LR,Aldrich BT,Greiner MA,Mullins RF,Worthington KS,Tucker BA,Wiley LA
33-9100 was used in Immunocytochemistry-immunoflourescence to devise a strategy for the derivation of corneal endothelial cells from adult fibroblast-derived induced pluripotent stem cells.
Tue May 08 00:00:00 EDT 2018
Increase in resistance to anticancer drugs involves occludin in spheroid culture model of lung adenocarcinoma A549 cells.
Scientific reports
Eguchi H,Akizuki R,Maruhashi R,Tsukimoto M,Furuta T,Matsunaga T,Endo S,Ikari A
33-9100 was used in Immunocytochemistry-immunoflourescence to investigate the regulatory mechanism and pathophysiological role of occludin.
Thu Oct 11 00:00:00 EDT 2018
Dapsone protects brain microvascular integrity from high-fat diet induced LDL oxidation.
Cell death & disease
Zhan R,Zhao M,Zhou T,Chen Y,Yu W,Zhao L,Zhang T,Wang H,Yang H,Jin Y,He Q,Yang X,Guo X,Willard B,Pan B,Huang Y,Chen Y,Chui D,Zheng L
33-9100 was used in Western Blotting to suggest the significance of dapsone in protecting brain microvessels under lipid metabolic disorders.
Thu Jun 07 00:00:00 EDT 2018
Optimisation of growth conditions for ovine airway epithelial cell differentiation at an air-liquid interface.
PloS one
O'Boyle N,Sutherland E,Berry CC,Davies RL
33-9100 was used in Immunocytochemistry-immunoflourescence to elucidate important differences between the response of ovine tracheal epithelial cells and other previously described airway epithelial models to a variety of environmental conditions.
Fri Jul 13 00:00:00 EDT 2018
A bioinspired microfluidic model of liquid plug-induced mechanical airway injury.
Biomicrofluidics
Song JW,Paek J,Park KT,Seo J,Huh D
33-9100 was used in Immunocytochemistry-immunoflourescence to allow for a novel biomimetic approach to modeling a complex and dynamic biophysical microenvironment of diseased human airways and may serve as an enabling platform for mechanistic investigation of key disease processes that drive the progression and exacerbation of obstructive pulmonary diseases.
Sun Jul 01 00:00:00 EDT 2018
Myosin1D is an evolutionarily conserved regulator of animal left-right asymmetry.
Nature communications
Juan T,Géminard C,Coutelis JB,Cerezo D,Polès S,Noselli S,Fürthauer M
33-9100 was used in Immunohistochemistry to identify Myosin1D as an evolutionarily conserved regulator of animal left-right asymmetry.
Wed May 16 00:00:00 EDT 2018
In Vitro Wounding Models Using the Electric Cell-Substrate Impedance Sensing (ECIS)-Zθ Technology.
Biosensors
Gu AY,Kho DT,Johnson RH,Graham ES,O'Carroll SJ
33-9100 was used in Immunocytochemistry to compare in vitro wound-healing using human cerebral microvascular endothelial cells with both single electrode (8W1E) and multiple electrodes (8W10E+) arrays.
Thu Oct 11 00:00:00 EDT 2018
Investigation of corneal endothelial changes post selective laser trabeculoplasty.
Clinical & experimental ophthalmology
Leahy KE,Madigan MC,Sarris M,Watson SL,McCluskey P,White AJ
33-9100 was used in Immunohistochemistry to determine the mechanism of transient corneal endothelial changes observed following SLT and show that similarity of the findings between SLT-treated and peroxide-treated corneas suggests that both conditions trigger changes at the level of endothelial tight junctions, perhaps triggered by liberation of free radicals as previously proposed.
Sat Sep 01 00:00:00 EDT 2018
Fish Scales Dictate the Pattern of Adult Skin Innervation and Vascularization.
Developmental cell
Rasmussen JP,Vo NT,Sagasti A
33-9100 was used in Immunohistochemistry to find that scales recruit, organize, and polarize axons and blood vessels to evenly distribute them in the skin.
Mon Aug 06 00:00:00 EDT 2018
CDC20B is required for deuterosome-mediated centriole production in multiciliated cells.
Nature communications
Revinski DR,Zaragosi LE,Boutin C,Ruiz-Garcia S,Deprez M,Thomé V,Rosnet O,Gay AS,Mercey O,Paquet A,Pons N,Ponzio G,Marcet B,Kodjabachian L,Barbry P
33-9100 was used in Immunohistochemistry-immunofluorescence to investigate the cell division cycle 20B gene in multiciliated cells.
Wed Nov 07 00:00:00 EST 2018
Medium throughput breathing human primary cell alveolus-on-chip model.
Scientific reports
Stucki JD,Hobi N,Galimov A,Stucki AO,Schneider-Daum N,Lehr CM,Huwer H,Frick M,Funke-Chambour M,Geiser T,Guenat OT
33-9100 was used in Immunocytochemistry-immunoflourescence to develop a 'breathing' lung-on-chip array equipped with a passive medium exchange mechanism, providing an in vivo-like environment to primary human lung alveolar cells and primary lung endothelial cells.
Tue Sep 25 00:00:00 EDT 2018
Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin-F-actin based oscillatory cell-cell interaction.
Nature communications
Paatero I,Sauteur L,Lee M,Lagendijk AK,Heutschi D,Wiesner C,Guzmán C,Bieli D,Hogan BM,Affolter M,Belting HG
33-9100 was used in Immunohistochemistry-immunofluorescence to suggest an oscillating ratchet-like mechanism, which is used by endothelial cells to move over each other in cell rearrangements.
Fri Aug 31 00:00:00 EDT 2018
Mathematical-model-guided development of full-thickness epidermal equivalent.
Scientific reports
Kumamoto J,Nakanishi S,Makita M,Uesaka M,Yasugahira Y,Kobayashi Y,Nagayama M,Denda S,Denda M
33-9100 was used in Immunohistochemistry-immunofluorescence to investigate whether the undulatory pattern of the papillary layer beneath the epidermis is a key determinant of epidermal thickness.
Thu Dec 20 00:00:00 EST 2018
HIPPO signaling resolves embryonic cell fate conflicts during establishment of pluripotency in vivo.
eLife
Frum T,Murphy TM,Ralston A
33-9100 was used in Immunohistochemistry-immunofluorescence to study the novel roles for the HIPPO signalling pathway in controlling cell positioning and expression of Sox2, the first marker of pluripotency in the mouse early embryo.
Tue Dec 11 00:00:00 EST 2018
Role of Alström syndrome 1 in the regulation of blood pressure and renal function.
JCI insight
Jaykumar AB,Caceres PS,King-Medina KN,Liao TD,Datta I,Maskey D,Naggert JK,Mendez M,Beierwaltes WH,Ortiz PA
33-9100 was used in Immunocytochemistry-immunoflourescence to point to ALMS1 as a potentially novel gene involved in BP and renal function regulation.
Fri Nov 02 00:00:00 EDT 2018
GPR40 receptor activation promotes tight junction assembly in airway epithelial cells via AMPK-dependent mechanisms.
Tissue barriers
Moonwiriyakit A,Wattanaphichet P,Chatsudthipong V,Muanprasat C
33-9100 was used in Immunocytochemistry to reveal an unprecedented role of GPR40 in facilitating airway epithelial tight junction assembly via PLC-CaMKKβ-AMPK pathways.
Tue Dec 11 00:00:00 EST 2018
Tridimensional visualization reveals direct communication between the embryo and glands critical for implantation.
Nature communications
Yuan J,Deng W,Cha J,Sun X,Borg JP,Dey SK
33-9100 was used in Immunohistochemistry-immunofluorescence to show that glands directly connecting to the crypt encasing the embryo during implantation are fundamental to pregnancy success.
Fri Feb 09 00:00:00 EST 2018
Dexamethasone enhances vasopressin-induced aquaporin-2 gene expression in the mpkCCD cells.
American journal of physiology. Renal physiology
Kuo KT,Yang CW,Yu MJ
33-9100 was used in Immunocytochemistry-immunoflourescence to facilitate the study of aquaporin-2 cell physiology regulated by vasopressin.
Thu Feb 01 00:00:00 EST 2018
Methylglyoxal Disrupts Paranodal Axoglial Junctions via Calpain Activation.
ASN neuro
Griggs RB,Yermakov LM,Drouet DE,Nguyen DVM,Susuki K
33-9100 was used in Immunofluorescence in immunohistochemistry on frozen tissues to show that increasing methylglyoxal produces paranodal disruption in both sciatic and optic nerves from wild-type mice.
Thu Jul 11 00:00:00 EDT 2019
Activated Microglia Disrupt the Blood-Brain Barrier and Induce Chemokines and Cytokines in a Rat in vitro Model.
Frontiers in cellular neuroscience
Shigemoto-Mogami Y,Hoshikawa K,Sato K
33-9100 was used in Western Blotting to investigate the interaction of microglia with blood-brain barrier cells.
Thu Oct 01 00:00:00 EDT 2020
Activated Microglia Disrupt the Blood-Brain Barrier and Induce Chemokines and Cytokines in a Rat in vitro Model.
Frontiers in cellular neuroscience
Shigemoto-Mogami Y,Hoshikawa K,Sato K
33-9100 was used in Western Blotting to investigate the interaction of microglia with blood-brain barrier cells.
Thu Oct 01 00:00:00 EDT 2020
Development and optimization of a differentiated airway epithelial cell model of the bovine respiratory tract.
Scientific reports
Cozens D,Grahame E,Sutherland E,Taylor G,Berry CC,Davies RL
33-9100 was used in Immunocytochemistry-immunoflourescence to develop an optimised model of differentiated airway epithelial cells in the bovine respiratory tract.
Tue Jan 16 00:00:00 EST 2018
Juxtanodin in retinal pigment epithelial cells: Expression and biological activities in regulating cell morphology and actin cytoskeleton organization.
The Journal of comparative neurology
Liang F,Hwang JH,Tang NW,Hunziker W
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to suggest possible roles of JN in RPE molecular transport, phagocytosis and formation of outer blood-retinal barrier, or possible involvement of JN expression perturbations in pathogenesis of such retinal disorders as proliferative vitreoretinopathy and age-related macular degeneration.
Thu Feb 01 00:00:00 EST 2018
Juxtanodin in retinal pigment epithelial cells: Expression and biological activities in regulating cell morphology and actin cytoskeleton organization.
The Journal of comparative neurology
Liang F,Hwang JH,Tang NW,Hunziker W
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to suggest possible roles of JN in RPE molecular transport, phagocytosis and formation of outer blood-retinal barrier, or possible involvement of JN expression perturbations in pathogenesis of such retinal disorders as proliferative vitreoretinopathy and age-related macular degeneration.
Thu Feb 01 00:00:00 EST 2018
The Epigenetic Factor KDM2B Regulates EMT and Small GTPases in Colon Tumor Cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zacharopoulou N,Tsapara A,Kallergi G,Schmid E,Alkahtani S,Alarifi S,Tsichlis PN,Kampranis SC,Stournaras C
33-9100 was used in Immunohistochemistry to examine the role of KDM2B in regulating EMT and small GTPase expression in colon tumour cells.
Tue Aug 21 00:00:00 EDT 2018
Improving Cell Survival in Injected Embryos Allows Primed Pluripotent Stem Cells to Generate Chimeric Cynomolgus Monkeys.
Cell reports
Kang Y,Ai Z,Duan K,Si C,Wang Y,Zheng Y,He J,Yin Y,Zhao S,Niu B,Zhu X,Liu L,Xiang L,Zhang L,Niu Y,Ji W,Li T
33-9100 was used in Immunohistochemistry-immunofluorescence to develop a method to understand pluripotency and broaden the use of embryonic chimeras for basic developmental biology research and regenerative medicine.
Tue Nov 27 00:00:00 EST 2018
Chiral Cilia Orientation in the Left-Right Organizer.
Cell reports
Ferreira RR,Pakula G,Klaeyle L,Fukui H,Vilfan A,Supatto W,Vermot J
33-9100 was used in Immunohistochemistry to identifies a different type of tissue asymmetry and sheds light on chirality genesis in developing tissues.
Tue Nov 20 00:00:00 EST 2018
Loss of KLF15 accelerates chronic podocyte injury.
International journal of molecular medicine
Han SS,Yu MY,Yoo KD,Lee JP,Kim DK,Kim YS,Yang SH
33-9100 was used in Western Blotting to investigate podocyte injury regulation by KLF15.
Sat Sep 01 00:00:00 EDT 2018
Blood-brain-barrier organoids for investigating the permeability of CNS therapeutics.
Nature protocols
Bergmann S,Lawler SE,Qu Y,Fadzen CM,Wolfe JM,Regan MS,Pentelute BL,Agar NYR,Cho CF
33-9100 was used in Immunocytochemistry to analyze drug penetration into the organoids: confocal fluorescence microscopy and mass spectrometry imaging.
Sat Dec 01 00:00:00 EST 2018
Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease.
Nature materials
Cruz NM,Song X,Czerniecki SM,Gulieva RE,Churchill AJ,Kim YK,Winston K,Tran LM,Diaz MA,Fu H,Finn LS,Pei Y,Himmelfarb J,Freedman BS
Wed Nov 01 00:00:00 EDT 2017
Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues.
Nature cell biology
Sugden WW,Meissner R,Aegerter-Wilmsen T,Tsaryk R,Leonard EV,Bussmann J,Hamm MJ,Herzog W,Jin Y,Jakobsson L,Denz C,Siekmann AF
33-9100 was used in Immunohistochemistry to examine the role of endoglin in modulating endothelial cell shape to control blood vessel diameter.
Thu Jun 01 00:00:00 EDT 2017
Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development.
Neuron
Thomas-Jinu S,Gordon PM,Fielding T,Taylor R,Smith BN,Snowden V,Blanc E,Vance C,Topp S,Wong CH,Bielen H,Williams KL,McCann EP,Nicholson GA,Pan-Vazquez A,Fox AH,Bond CS,Talbot WS,Blair IP,Shaw CE,Houart C
33-9100 was used in Immunohistochemistry-wholemount to uncover the axonal function of the splicing factor SFPQ in motor development and highlight the importance of the coiled-coil domain in this process.
Wed Apr 19 00:00:00 EDT 2017
The Wnt Inhibitor Apcdd1 Coordinates Vascular Remodeling and Barrier Maturation of Retinal Blood Vessels.
Neuron
Mazzoni J,Smith JR,Shahriar S,Cutforth T,Ceja B,Agalliu D
33-9100 was used in Immunohistochemistry-immunofluorescence to study how the canonical Norrin/Fz4/Lrp5/6 pathway coordinates angiogenesis, vascular remodelling, and barrier maturation.
Wed Dec 06 00:00:00 EST 2017
Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue.
Developmental cell
Cao J,Wang J,Jackman CP,Cox AH,Trembley MA,Balowski JJ,Cox BD,De Simone A,Dickson AL,Di Talia S,Small EM,Kiehart DP,Bursac N,Poss KD
33-9100 was used in Immunohistochemistry-immunofluorescence to provide evidence that mechanical tension can regulate cell-cycle dynamics in regenerating tissue, stratifying the source cell features to improve repair.
Mon Sep 25 00:00:00 EDT 2017
Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo.
Developmental cell
Roh-Johnson M,Shah AN,Stonick JA,Poudel KR,Kargl J,Yang GH,di Martino J,Hernandez RE,Gast CE,Zarour LR,Antoku S,Houghton AM,Bravo-Cordero JJ,Wong MH,Condeelis J,Moens CB
33-9100 was used in Immunohistochemistry-immunofluorescence to study and visualise tumour cells and their interactions with macrophages in zebrafish.
Mon Dec 04 00:00:00 EST 2017
The Physical Basis of Coordinated Tissue Spreading in Zebrafish Gastrulation.
Developmental cell
Morita H,Grigolon S,Bock M,Krens SF,Salbreux G,Heisenberg CP
33-9100 was used in Immunohistochemistry to show that coordinated tissue expansion and thinning during doming relies on surface cells simultaneously controlling tissue surface tension and radial tissue contraction.
Mon Feb 27 00:00:00 EST 2017
Asymmetry of an Intracellular Scaffold at Vertebrate Electrical Synapses.
Current biology : CB
Marsh AJ,Michel JC,Adke AP,Heckman EL,Miller AC
33-9100 was used in Immunohistochemistry-immunofluorescence to study the requirement of tight junction protein 1b in the formation of electrical synapses in vivo.
Mon Nov 20 00:00:00 EST 2017
Type I and Type III Interferons Display Different Dependency on Mitogen-Activated Protein Kinases to Mount an Antiviral State in the Human Gut.
Frontiers in immunology
Pervolaraki K,Stanifer ML,Münchau S,Renn LA,Albrecht D,Kurzhals S,Senís E,Grimm D,Schröder-Braunstein J,Rabin RL,Boulant S
33-9100 was used in Western Blotting to suggest that type III interferon constitutes the frontline of antiviral response in the human gut.
Mon Mar 21 00:00:00 EDT 2022
An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells.
The Journal of cell biology
Taniguchi K,Shao Y,Townshend RF,Cortez CL,Harris CE,Meshinchi S,Kalantry S,Fu J,O'Shea KS,Gumucio DL
33-9100 was used in Immunocytochemistry-immunoflourescence to demonstrate that apical polarisation begins on the interior of single human pluripotent stem cells through the dynamic formation of a highly organised perinuclear apicosome structure.
Mon Dec 04 00:00:00 EST 2017
Adenohypophysis placodal precursors exhibit distinctive features within the rostral preplacodal ectoderm.
Development (Cambridge, England)
Sanchez-Arrones L,Sandonís Á,Cardozo MJ,Bovolenta P
33-9100 was used in Immunohistochemistry to propose that adenohypophyseal placode precursors are unique within the preplacodal ectoderm possibly because they originate the only single placode and the only one with an endocrine character.
Sun Oct 01 00:00:00 EDT 2017
Distinct and redundant functions of Esama and VE-cadherin during vascular morphogenesis.
Development (Cambridge, England)
Sauteur L,Affolter M,Belting HG
33-9100 was used in Immunohistochemistry-immunofluorescence to compare the contributions of VE-cadherin and Esama during angiogenic sprouting and blood vessel fusion in the zebrafish embryo.
Sat Apr 15 00:00:00 EDT 2017
Perineurial Glial Plasticity and the Role of TGF-β in the Development of the Blood-Nerve Barrier.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Morris AD,Lewis GM,Kucenas S
33-9100 was used in Immunohistochemistry-wholemount to study perineurial glial development, maturation, and response to injury in zebrafish.
Wed May 03 00:00:00 EDT 2017
Sec24C-Dependent Transport of Claudin-1 Regulates Hepatitis C Virus Entry.
Journal of virology
Yin P,Li Y,Zhang L
33-9100 was used in Western Blotting to identify an interaction between claudin-1 and Sec24C which regulates Hepatitis C virus entry.
Fri Sep 15 00:00:00 EDT 2017
CRB3 downregulation confers breast cancer stem cell traits through TAZ/β-catenin.
Oncogenesis
Li P,Wang Y,Mao X,Jiang Y,Liu J,Li J,Wang J,Wang R,She J,Zhang J,Yang J,Liu Y,Liu P
33-9100 was used in Western Blotting to examine how cancer stem cells acquire their unique traits in self-renewal to sustain the cancer even if other cells are eliminated.
Mon Apr 24 00:00:00 EDT 2017
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development.
Stem cells (Dayton, Ohio)
Kim YK,Refaeli I,Brooks CR,Jing P,Gulieva RE,Hughes MR,Cruz NM,Liu Y,Churchill AJ,Wang Y,Fu H,Pippin JW,Lin LY,Shankland SJ,Vogl AW,McNagny KM,Freedman BS
33-9100 was used in Immunohistochemistry-immunofluorescence to study how podocytes derived from human pluripotent stem cells phenocopy mammalian podocytes at the capillary loop stage.
Fri Dec 01 00:00:00 EST 2017
Zonula occludens-1/NF-κB/CXCL8: a new regulatory axis for tumor angiogenesis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Lesage J,Suarez-Carmona M,Neyrinck-Leglantier D,Grelet S,Blacher S,Hunziker W,Birembaut P,Noël A,Nawrocki-Raby B,Gilles C,Polette M
339100 was used in immunocytochemistry, immunohistochemistry, and western blot to evaluate the functional involvement of zonula occludens-1 in CXCL8/IL-8 chemokine expression in lung and breast tumor cells
Sat Apr 01 00:00:00 EDT 2017
A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells.
Cellular signalling
Dukic AR,Haugen LH,Pidoux G,Leithe E,Bakke O,Taskén K
339100 was used in immunohistochemistry and western blot to evaluate if Ezrin associates with connexin 43 in cell types that form stable gap junctions and serve as an A kinase anchoring protein
Sat Apr 01 00:00:00 EDT 2017
Efficient Differentiation of TBX18+/WT1+ Epicardial-Like Cells from Human Pluripotent Stem Cells Using Small Molecular Compounds.
Stem cells and development
Zhao J,Cao H,Tian L,Huo W,Zhai K,Wang P,Ji G,Ma Y
33-9100 was used in Immunocytochemistry-immunoflourescence to report coexpression of TBX18 and WT1 in the majority of epicardial cells during mouse embryonic epicardial development.
Sat Apr 01 00:00:00 EDT 2017
Spontaneous acquisition of infinite proliferative capacity by a rabbit corneal endothelial cell line with maintenance of phenotypic and physiological characteristics.
Journal of tissue engineering and regenerative medicine
Kageyama T,Hayashi R,Hara S,Yoshikawa K,Ishikawa Y,Yamato M,Nishida K
33-9100 was used in immunohistochemistry and western blot to generate and characterize a novel rabbit corneal endothelial cell line.
Sat Apr 01 00:00:00 EDT 2017
Spontaneous acquisition of infinite proliferative capacity by a rabbit corneal endothelial cell line with maintenance of phenotypic and physiological characteristics.
Journal of tissue engineering and regenerative medicine
Kageyama T,Hayashi R,Hara S,Yoshikawa K,Ishikawa Y,Yamato M,Nishida K
33-9100 was used in immunohistochemistry and western blot to generate and characterize a novel rabbit corneal endothelial cell line.
Sat Apr 01 00:00:00 EDT 2017
A Bruch's membrane substitute fabricated from silk fibroin supports the function of retinal pigment epithelial cells in vitro.
Journal of tissue engineering and regenerative medicine
Shadforth AMA,Suzuki S,Theodoropoulos C,Richardson NA,Chirila TV,Harkin DG
33-9100 was used in immunocytochemistry to examine the function of retinal pigment epithelial cells in vitro.
Thu Jun 01 00:00:00 EDT 2017
Calibrated flux measurements reveal a nanostructure-stimulated transcytotic pathway.
Experimental cell research
Stewart T,Koval WT,Molina SA,Bock SM,Lillard JW,Ross RF,Desai TA,Koval M
33-9100 was used in Immunocytochemistry-immunoflourescence to study the stimulation of transcytosis by nanostructured films, and measure the increased paracellular permeability.
Thu Jun 15 00:00:00 EDT 2017
Target Intestinal Microbiota to Alleviate Disease Progression in Amyotrophic Lateral Sclerosis.
Clinical therapeutics
Zhang YG,Wu S,Yi J,Xia Y,Jin D,Zhou J,Sun J
33-9100 was used in Western Blotting to provide evidence that intestinal dysfunction and dysbiosis may actively contribute to amyotrophic lateral sclerosis pathophysiology.
Wed Feb 01 00:00:00 EST 2017
Visualizing the dynamic coupling of claudin strands to the actin cytoskeleton through ZO-1.
Molecular biology of the cell
Van Itallie CM,Tietgens AJ,Anderson JM
339100 was used in immunocytochemistry and western blot to visualize the interaction of claudin, ZO-1 and actin in epithelial tight juntions.
Wed Feb 15 00:00:00 EST 2017
ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens.
Molecular biology of the cell
Priya R,Liang X,Teo JL,Duszyc K,Yap AS,Gomez GA
339100 was used in immunocytochemistry to analyze differential functional effects for rho kinases 1 and 2 at the epithelial zonula adherens
Sun Jan 01 00:00:00 EST 2017
Comparative analysis of monoaminergic cerebrospinal fluid-contacting cells in Osteichthyes (bony vertebrates).
The Journal of comparative neurology
Xavier AL,Fontaine R,Bloch S,Affaticati P,Jenett A,Demarque M,Vernier P,Yamamoto K
33-9100 was used in Immunohistochemistry-immunofluorescence to compare the organisation of cerebrospinal fluid-contacting cells in chicken, Xenopus, and zebrafish.
Thu Jun 15 00:00:00 EDT 2017
ECIS technology reveals that monocytes isolated by CD14+ve selection mediate greater loss of BBB integrity than untouched monocytes, which occurs to a greater extent with IL-1β activated endothelium in comparison to TNFα.
PloS one
Kho DT,Johnson R,Robilliard L,du Mez E,McIntosh J,O'Carroll SJ,Angel CE,Graham ES
33-9100 was used in Immunocytochemistry to assess whether brain endothelial cells activated by IL-1Β or TNFα differ in their interaction with monocytes.
Wed Sep 27 00:00:00 EDT 2017
Cell Division Cycle 42 plays a Cell type-Specific role in Lung Tumorigenesis.
Scientific reports
Zheng C,Wang Y,Yang L,Zhou S,Gao Y,Li F,Feng Y,Wang Z,Zhan L,Yan Q,Zhu X,Wong KK,Chen Z,Ji H
Mon Sep 04 00:00:00 EDT 2017
Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly.
eLife
Bloomekatz J,Singh R,Prall OW,Dunn AC,Vaughan M,Loo CS,Harvey RP,Yelon D
33-9100 was used in Immunohistochemistry-immunofluorescence to demonstrate a novel mechanism through which endodermal-myocardial communication can guide the cell movements that initiate cardiac morphogenesis.
Wed Jan 18 00:00:00 EST 2017
The cell adhesion molecule BT-IgSF is essential for a functional blood-testis barrier and male fertility in mice.
The Journal of biological chemistry
Pelz L,Purfürst B,Rathjen FG
33-9100 was used in Immunohistochemistry to indicate that BT-IgSF is expressed at the BTB and is required for male fertility by supporting the functional integrity of the BTB.
Fri Dec 29 00:00:00 EST 2017
HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development.
eLife
Connell M,Chen H,Jiang J,Kuan CW,Fotovati A,Chu TL,He Z,Lengyell TC,Li H,Kroll T,Li AM,Goldowitz D,Frappart L,Ploubidou A,Patel MS,Pilarski LM,Simpson EM,Lange PF,Allan DW,Maxwell CA
33-9100 was used in Immunocytochemistry to identify an essential role for HMMR in the PLK1-dependent regulatory pathway that orients progenitor cell division and supports neural development.
Tue Oct 10 00:00:00 EDT 2017
HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development.
eLife
Connell M,Chen H,Jiang J,Kuan CW,Fotovati A,Chu TL,He Z,Lengyell TC,Li H,Kroll T,Li AM,Goldowitz D,Frappart L,Ploubidou A,Patel MS,Pilarski LM,Simpson EM,Lange PF,Allan DW,Maxwell CA
33-9100 was used in Immunocytochemistry to identify an essential role for HMMR in the PLK1-dependent regulatory pathway that orients progenitor cell division and supports neural development.
Tue Oct 10 00:00:00 EDT 2017
HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development.
eLife
Connell M,Chen H,Jiang J,Kuan CW,Fotovati A,Chu TL,He Z,Lengyell TC,Li H,Kroll T,Li AM,Goldowitz D,Frappart L,Ploubidou A,Patel MS,Pilarski LM,Simpson EM,Lange PF,Allan DW,Maxwell CA
33-9100 was used in Immunocytochemistry to identify an essential role for HMMR in the PLK1-dependent regulatory pathway that orients progenitor cell division and supports neural development.
Tue Oct 10 00:00:00 EDT 2017
HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development.
eLife
Connell M,Chen H,Jiang J,Kuan CW,Fotovati A,Chu TL,He Z,Lengyell TC,Li H,Kroll T,Li AM,Goldowitz D,Frappart L,Ploubidou A,Patel MS,Pilarski LM,Simpson EM,Lange PF,Allan DW,Maxwell CA
33-9100 was used in Immunocytochemistry to identify an essential role for HMMR in the PLK1-dependent regulatory pathway that orients progenitor cell division and supports neural development.
Tue Oct 10 00:00:00 EDT 2017
Phenotypic screening identifies Axl kinase as a negative regulator of an alveolar epithelial cell phenotype.
Laboratory investigation; a journal of technical methods and pathology
Fujino N,Kubo H,Maciewicz RA
33-9100 was used in ELISA, Immunocytochemistry, Western Blot, Immunohistochemistry to suggest that the Axl kinase signaling pathway is associated with the loss integrity of alveolar epithelium in pathological remodeling of human lung diseases.
Fri Sep 01 00:00:00 EDT 2017
Temporal dynamics of ovine airway epithelial cell differentiation at an air-liquid interface.
PloS one
O'Boyle N,Sutherland E,Berry CC,Davies RL
33-9100 was used in Immunohistochemistry-immunofluorescence to analyse the progression of differentiation in ovine tracheal epithelial cells over an extensive time course, at an air-liquid interface.
Mon Oct 23 00:00:00 EDT 2017
Targeting Neph1 and ZO-1 protein-protein interaction in podocytes prevents podocyte injury and preserves glomerular filtration function.
Scientific reports
Sagar A,Arif E,Solanki AK,Srivastava P,Janech MG,Kim SH,Lipschutz JH,Kwon SH,Nihalani D
33-9100 was used in Western Blot to investigate the therapeutic benefits of stabilising protein-protein interaction in podocytes to prevent podocyte injury and preserve glomerular filtration function.
Thu Sep 21 00:00:00 EDT 2017
Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration.
PloS one
Geng Z,Walsh PJ,Truong V,Hill C,Ebeling M,Kapphahn RJ,Montezuma SR,Yuan C,Roehrich H,Ferrington DA,Dutton JR
339100 was used in immunohistochemistry to establish an application to generate retinal pigmented epithelium from induced pluripotent stem cells
Thu Aug 17 00:00:00 EDT 2017
Modeling Group B Streptococcus and Blood-Brain Barrier Interaction by Using Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells.
mSphere
Kim BJ,Bee OB,McDonagh MA,Stebbins MJ,Palecek SP,Doran KS,Shusta EV
33-9100 was used in Immunocytochemistry-immunoflourescence to evaluate whether induced pluripotent stem cell-derived brain microvascular endothelial cells are appropriate for modelling bacterial interaction with the blood-brain barrier.
Wed Nov 20 00:00:00 EST 2019
Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium.
EBioMedicine
Zhang W,Li H,Ogando DG,Li S,Feng M,Price FW,Tennessen JM,Bonanno JA
33-9100 was used in immunohistochemistry - paraffin section to study factors that regulate metabolism in the corneal endothelium
Wed Feb 01 00:00:00 EST 2017
Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality.
PloS one
Kim JG,Bae SJ,Lee HS,Park JH,Kim KW
33-9100 was used in Immunohistochemistry-immunofluorescence to investigate the role of claudin5a in the Zebrafish Kupffer's vesicle lumen.
Fri Oct 06 00:00:00 EDT 2017
Role and regulation of Yap in KrasG12D-induced lung cancer.
Oncotarget
Mao Y,Sun S,Irvine KD
33-9100 was used in Immunohistochemistry to assess the role and regulation of Yap in KrasG12D-induced lung cancer.
Tue Dec 19 00:00:00 EST 2017
Cross-over endocytosis of claudins is mediated by interactions via their extracellular loops.
PloS one
Gehne N,Lamik A,Lehmann M,Haseloff RF,Andjelkovic AV,Blasig IE
33-9100 was used in Immunocytochemistry to study the role of cross-over endocytosis in allowing tight junction remodelling while maintaining barrier integrity.
Fri Oct 13 00:00:00 EDT 2017
Analgesic drug delivery via recombinant tissue plasminogen activator and microRNA-183-triggered opening of the blood-nerve barrier.
Biomaterials
Yang S,Krug SM,Heitmann J,Hu L,Reinhold AK,Sauer S,Bosten J,Sommer C,Fromm M,Brack A,Rittner HL
33-9100 was used in immunocytochemistry to study the effect of microRNA-183 and analgesic drug delivery by recombinant tissue plasminogen activator in opening of the blood-nerve barrier
Tue Mar 01 00:00:00 EST 2016
Spemann organizer gene Goosecoid promotes delamination of neuroblasts from the otic vesicle.
Proceedings of the National Academy of Sciences of the United States of America
Kantarci H,Gerberding A,Riley BB
33-9100 was used in Immunohistochemistry-wholemount to demonstrate that Goosecoid, best known for regulating cellular dynamics in the Spemann organizer, regulates delamination of neuroblasts in the otic vesicle.
Tue Nov 01 00:00:00 EDT 2016
Planar cell polarity signaling in the uterus directs appropriate positioning of the crypt for embryo implantation.
Proceedings of the National Academy of Sciences of the United States of America
Yuan J,Cha J,Deng W,Bartos A,Sun X,Ho HH,Borg JP,Yamaguchi TP,Yang Y,Dey SK
339100 was used in immunohistochemistry to suggest that planar cell polarity signaling governs directed epithelial evaginations to form crypts for implantation in mice
Tue Dec 13 00:00:00 EST 2016
The barrier function of organotypic non-melanoma skin cancer models.
Journal of controlled release : official journal of the Controlled Release Society
Zoschke C,Ulrich M,Sochorová M,Wolff C,Vávrová K,Ma N,Ulrich C,Brandner JM,Schäfer-Korting M
33-9100 was used in immunocytochemistry to characterize barrier function in skin cancer models of organotypic non-melanoma
Sun Jul 10 00:00:00 EDT 2016
Functional Kidney Bioengineering with Pluripotent Stem-Cell-Derived Renal Progenitor Cells and Decellularized Kidney Scaffolds.
Advanced healthcare materials
Du C,Narayanan K,Leong MF,Ibrahim MS,Chua YP,Khoo VM,Wan AC
33-9100 was used in flow cytometry and immunocytochemistry to elucidate functional kidney bioengineering with decellularized kidney scaffolds and pluripotent stem-cell-derived renal progenitor cells
Mon Aug 01 00:00:00 EDT 2016
Cyp26 Enzymes Facilitate Second Heart Field Progenitor Addition and Maintenance of Ventricular Integrity.
PLoS biology
Rydeen AB,Waxman JS
33-9100 was used in Immunohistochemistry to study the mechanisms underlying retinoic acid-induced outflow tract malformations.
Tue Nov 01 00:00:00 EDT 2016
Bacillus anthracis spore movement does not require a carrier cell and is not affected by lethal toxin in human lung models.
Microbes and infection
Booth JL,Duggan ES,Patel VI,Langer M,Wu W,Braun A,Coggeshall KM,Metcalf JP
33-9100 was used in immunocytochemistry to assess how spore movement of Bacillus anthracis does not require a carrier cell and is not affected by lethal toxin in human lung models
Sat Oct 01 00:00:00 EDT 2016
The aPKC/Par3/Par6 Polarity Complex and Membrane Order Are Functionally Interdependent in Epithelia During Vertebrate Organogenesis.
Traffic (Copenhagen, Denmark)
Abu-Siniyeh A,Owen DM,Benzing C,Rinkwitz S,Becker TS,Majumdar A,Gaus K
33-9100 was used in immunohistochemistry to study membrane development in the gut, kidney, and liver ductal epithelia in zebrafish.
Fri Jan 01 00:00:00 EST 2016
Lack of CAR impacts neuronal function and cerebrovascular integrity in vivo.
Experimental neurology
Boussadia B,Gangarossa G,Mselli-Lakhal L,Rousset MC,de Bock F,Lassere F,Ghosh C,Pascussi JM,Janigro D,Marchi N
33-9100 was used in Western Blotting to investigate whether the impact of constitutive androstane nuclear receptors on neurophysiology and behaviour is underlined by cerebrovascular-neuronal modifications.
Thu Sep 01 00:00:00 EDT 2016
Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II.
Cell cycle (Georgetown, Tex.)
Priya R,Wee K,Budnar S,Gomez GA,Yap AS,Michael M
33-9100 was used in Immunocytochemistry to demonstrate a key role for Coronin 1B in maintaining a junctional pool of non-muscle Myosin II.
Wed Nov 16 00:00:00 EST 2016
Human Urinary Epithelial Cells as a Source of Engraftable Hepatocyte-Like Cells Using Stem Cell Technology.
Cell transplantation
Sauer V,Tchaikovskaya T,Wang X,Li Y,Zhang W,Tar K,Polgar Z,Ding J,Guha C,Fox IJ,Roy-Chowdhury N,Roy-Chowdhury J
33-9100 was used in Immunocytochemistry to report reprogramming of human urinary epithelial cells into iPSCs and subsequent hepatic differentiation followed by a detailed characterisation of the new iHeps.
Tue Dec 13 00:00:00 EST 2016
Vitamin D/VDR signaling attenuates lipopolysaccharide‑induced acute lung injury by maintaining the integrity of the pulmonary epithelial barrier.
Molecular medicine reports
Shi YY,Liu TJ,Fu JH,Xu W,Wu LL,Hou AN,Xue XD
33-9100 was used in immunohistochemistry - paraffin section and western blot to test if vitamin D signaling ameliorates lipopolysaccharide-induced acute lung injury by altering barrier integrity
Mon Feb 01 00:00:00 EST 2016
Vascular development in the vertebrate pancreas.
Developmental biology
Azizoglu DB,Chong DC,Villasenor A,Magenheim J,Barry DM,Lee S,Marty-Santos L,Fu S,Dor Y,Cleaver O
33-9100 was used in Immunofluorescence in immunohistochemistry on frozen tissues to show that pancreatic epithelial branches intercalate with the fine capillary plexus of the surrounding pancreatic mesenchyme.
Thu Dec 01 00:00:00 EST 2016
Intracellular Golgi Complex organization reveals tissue specific polarity during zebrafish embryogenesis.
Developmental dynamics : an official publication of the American Association of Anatomists
Sepich DS,Solnica-Krezel L
33-9100 was used in immunohistochemistry - free floating to investigate tissue specific polarity during zebrafish embryogenesis by intracellular golgi complex organization
Wed Jun 01 00:00:00 EDT 2016
A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells.
Molecular vision
Di Lauro S,Rodriguez-Crespo D,Gayoso MJ,Garcia-Gutierrez MT,Pastor JC,Srivastava GK,Fernandez-Bueno I
33-9100 was used in immunocytochemistry to characterize coculture model of retinal pigment epithelium cells and porcine central neuroretina explants
Tue Nov 08 00:00:00 EST 2016
Supervillin Is a Component of the Hair Cell's Cuticular Plate and the Head Plates of Organ of Corti Supporting Cells.
PloS one
Pollock LM,Gupta N,Chen X,Luna EJ,McDermott BM
33-9100 was used in Immunofluorescence to suggest that supervillin protein may shape the surface structure of the organ of Corti.
Wed Jul 26 00:00:00 EDT 2017
A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes.
JCI insight
Grahammer F,Wigge C,Schell C,Kretz O,Patrakka J,Schneider S,Klose M,Kind J,Arnold SJ,Habermann A,Bräuniger R,Rinschen MM,Völker L,Bregenzer A,Rubbenstroth D,Boerries M,Kerjaschki D,Miner JH,Walz G,Benzing T,Fornoni A,Frangakis AS,Huber TB
33-9100 was used in immunohistochemistry determine the genetic factors that regulate slit diaphragm architecture
Thu Jun 16 00:00:00 EDT 2016
Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5.
PloS one
Huang LY,Stuart C,Takeda K,D'Agnillo F,Golding B
33-9100 was used in immunocytochemistry and western blot assess the effect of polyinosinic-polycytidylic acid on the barrier function and tight junction integrity of primary human lung microvascular endothelial cells
Fri Aug 04 00:00:00 EDT 2017
Melatonin Preserves Blood-Brain Barrier Integrity and Permeability via Matrix Metalloproteinase-9 Inhibition.
PloS one
Alluri H,Wilson RL,Anasooya Shaji C,Wiggins-Dohlvik K,Patel S,Liu Y,Peng X,Beeram MR,Davis ML,Huang JH,Tharakan B
33-9100 was used in Western Blotting to study the mechanism responsible for maintaining blood-brain barrier integrity and permeability.
Tue Jul 11 00:00:00 EDT 2017
Skin-on-a-chip model simulating inflammation, edema and drug-based treatment.
Scientific reports
Wufuer M,Lee G,Hur W,Jeon B,Kim BJ,Choi TH,Lee S
339100 was used in immunocytochemistry to develop and characterize a 3 layered 'skin-on-a-chip' model
Mon Nov 21 00:00:00 EST 2016
Salmonella enteritidis Effector AvrA Stabilizes Intestinal Tight Junctions via the JNK Pathway.
The Journal of biological chemistry
Lin Z,Zhang YG,Xia Y,Xu X,Jiao X,Sun J
339100 was used in immunohistochemistry - paraffin section and western blot to examine the role of Salmonella AvrA during infection
Fri Dec 23 00:00:00 EST 2016
Isolated Human Pulmonary Artery Structure and Function Pre- and Post-Cardiopulmonary Bypass Surgery.
Journal of the American Heart Association
Dora KA,Stanley CP,Al Jaaly E,Fiorentino F,Ascione R,Reeves BC,Angelini GD
33-9100 was used in immunohistochemistry to characterize the structure and function of the isolated human pulmonary artery pre- and post-cardiopulmonary bypass surgery
Tue Feb 23 00:00:00 EST 2016
A critical role for NF2 and the Hippo pathway in branching morphogenesis.
Nature communications
Reginensi A,Enderle L,Gregorieff A,Johnson RL,Wrana JL,McNeill H
33-9100 was used in immunohistochemistry investigate the roles of NF2, LATS1/2, and YAP in the branching morphogenesis of the mouse kidney
Tue Aug 02 00:00:00 EDT 2016
Attenuation of Blood-Brain Barrier Breakdown and Hyperpermeability by Calpain Inhibition.
The Journal of biological chemistry
Alluri H,Grimsley M,Anasooya Shaji C,Varghese KP,Zhang SL,Peddaboina C,Robinson B,Beeram MR,Huang JH,Tharakan B
33-9100 was used in Immunocytochemistry to test the effect of calpain inhibition on the BBB following traumatic insults to the brain.
Fri Dec 30 00:00:00 EST 2016
A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development.
The Journal of biological chemistry
Kitayama M,Mizutani K,Maruoka M,Mandai K,Sakakibara S,Ueda Y,Komori T,Shimono Y,Takai Y
33-9100 was used in immunocytochemistry to characterize prolactin receptor signaling for mammary gland development by a novel nectin-mediated cell adhesion apparatus
Fri Mar 11 00:00:00 EST 2016
The C-terminal domain controls the mobility of Crumbs 3 isoforms.
Biochimica et biophysica acta
Djuric I,Siebrasse JP,Schulze U,Granado D,Schlüter MA,Kubitscheck U,Pavenstädt H,Weide T
33-9100 was used in immunocytochemistry to examine the localization of Crb3A and Crb3B in epithelial cells
Wed Jun 01 00:00:00 EDT 2016
Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension.
Nature communications
Lee NK,Fok KW,White A,Wilson NH,O'Leary CJ,Cox HL,Michael M,Yap AS,Cooper HM
33-9100 was used in immunocytochemistry to maintain adherens junction stability and tension by neogenin recruitment of the WAVE regulatory complex
Thu Mar 31 00:00:00 EDT 2016
Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions.
Nature cell biology
Priya R,Gomez GA,Budnar S,Verma S,Cox HL,Hamilton NA,Yap AS
33-9100 was used in immunocytochemistry to identify factors that regulate the stability of the RhoA zone
Thu Oct 01 00:00:00 EDT 2015
ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization.
The Journal of cell biology
Bruurs LJ,Donker L,Zwakenberg S,Zwartkruis FJ,Begthel H,Knisely AS,Posthuma G,van de Graaf SF,Paulusma CC,Bos JL
33-9100 was used in immunohistochemistry to examine the role of Cdc42 in enterocyte polarization
Mon Sep 28 00:00:00 EDT 2015
LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation.
The Journal of cell biology
Sohet F,Lin C,Munji RN,Lee SY,Ruderisch N,Soung A,Arnold TD,Derugin N,Vexler ZS,Yen FT,Daneman R
33-9100 was used in immunohistochemistry - frozen section to investigate the role of LSR/angulin-1 in blood-brain barrier formation
Mon Mar 16 00:00:00 EDT 2015
Deep-brain stimulation associates with improved microvascular integrity in the subthalamic nucleus in Parkinson's disease.
Neurobiology of disease
Pienaar IS,Lee CH,Elson JL,McGuinness L,Gentleman SM,Kalaria RN,Dexter DT
33-9100 was used in immunohistochemistry to investigate the efficacy of deep-brain stimulation on microvascular integrity in the subthalamic nucleus in Parkinson disease.
Sun Feb 01 00:00:00 EST 2015
Immune quiescence of the brain is set by astroglial connexin 43.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Boulay AC,Mazeraud A,Cisternino S,Saubaméa B,Mailly P,Jourdren L,Blugeon C,Mignon V,Smirnova M,Cavallo A,Ezan P,Avé P,Dingli F,Loew D,Vieira P,Chrétien F,Cohen-Salmon M
33-9100 was used in western blot to study the role of astroglial cx43 in immune quiescence of the brain.
Wed Mar 11 00:00:00 EDT 2015
The relative balance of GM-CSF and TGF-β1 regulates lung epithelial barrier function.
American journal of physiology. Lung cellular and molecular physiology
Overgaard CE,Schlingmann B,Dorsainvil White S,Ward C,Fan X,Swarnakar S,Brown LA,Guidot DM,Koval M
33-9100 was used in immunocytochemistry to test if the relative balance of GM-CSF and TGF-β signaling regulates lung epithelial barrier function.
Mon Jun 15 00:00:00 EDT 2015
Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation.
Investigative ophthalmology & visual science
Sugiyama Y,Shelley EJ,Badouel C,McNeill H,McAvoy JW
33-9100 was used in immunohistochemistry - paraffin section to determine the contributions of Fat1 and Fat4 in eye development.
Mon Jun 01 00:00:00 EDT 2015
WNT3 and membrane-associated β-catenin regulate trophectoderm lineage differentiation in human blastocysts.
Molecular human reproduction
Krivega M,Essahib W,Van de Velde H
33-9100 was used in immunocytochemistry to investigate the role of WNT/β-catenin signaling during human preimplantation embryo development.
Tue Sep 01 00:00:00 EDT 2015
Effect of differentiation on endocytic profiles of endothelial and epithelial cell culture models.
Experimental cell research
Ilina P,Partti S,Niklander J,Ruponen M,Lou YR,Yliperttula M
33-9100 was used in immunocytochemistry to investigate the changes in endocytosis during differentiation.
Sun Mar 01 00:00:00 EST 2015
Expression and function of transcription factor AP-2? in early embryonic development of porcine parthenotes.
Reproduction, fertility, and development
Lee SH,Kwon JW,Choi I,Kim NH
33-9100 was used in immunohistochemistry to characterize transcription factor AP-2gamma in early embryonic development of porcine parthenotes
Wed Jan 07 00:00:00 EST 2015
Optimization of immunostaining on flat-mounted human corneas.
Molecular vision
Forest F,Thuret G,Gain P,Dumollard JM,Peoc'h M,Perrache C,He Z
33-9100 was used in immunocytochemistry to analyze flat-mounted human corneas by optimizing immunostaining
Mon Sep 26 00:00:00 EDT 2016
Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells.
Journal of neuroinflammation
O'Carroll SJ,Kho DT,Wiltshire R,Nelson V,Rotimi O,Johnson R,Angel CE,Graham ES
33-9100 was used in immunocytochemistry to determine the differential regulation of the inflammatory phenotype of brain microvascular endothelial cells by pro-inflammatory TNFalpha and IL-1beta
Wed Jul 08 00:00:00 EDT 2015
NF-κB inhibitors impair lung epithelial tight junctions in the absence of inflammation.
Tissue barriers
Ward C,Schlingmann B,Stecenko AA,Guidot DM,Koval M
33-9100 was used in immunohistochemistry to investigate the effect of NF-kappaB inhibitors on lung epithelial tight junctions in the absence of inflammation
Fri Apr 03 00:00:00 EDT 2015
DAPIT Over-Expression Modulates Glucose Metabolism and Cell Behaviour in HEK293T Cells.
PloS one
Kontro H,Cannino G,Rustin P,Dufour E,Kainulainen H
33-9100 was used in western blot to discuss the consequences of Diabetes Associated Protein in Insulin-sensitive Tissues overexpression
Tue Apr 19 00:00:00 EDT 2016
Prostacyclin prevents pericyte loss and demyelination induced by lysophosphatidylcholine in the central nervous system.
The Journal of biological chemistry
Muramatsu R,Kuroda M,Matoba K,Lin H,Takahashi C,Koyama Y,Yamashita T
33-9100 was used in western blot to investigate the effect of prostacyclin on pericyte loss and demyelination induced by lysophosphatidylcholine in the central nervous system
Fri May 01 00:00:00 EDT 2015
The human urothelial tight junction: claudin 3 and the ZO-1α+ switch.
Bladder (San Francisco, Calif.)
Smith NJ,Hinley J,Varley CL,Eardley I,Trejdosiewicz LK,Southgate J
33-9100 was used in immunocytochemistry, immunohistochemistry - paraffin section, and western blot to test if claudin 3 plays an instigating and/or a functional role in the urothelial tight junctions.
Fri Mar 18 00:00:00 EDT 2022
Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.
Oncotarget
Momeny M,Saunus JM,Marturana F,McCart Reed AE,Black D,Sala G,Iacobelli S,Holland JD,Yu D,Da Silva L,Simpson PT,Khanna KK,Chenevix-Trench G,Lakhani SR
33-9100 was used in western blot to study human breast cancer cell lines and how Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration
Sat Feb 28 00:00:00 EST 2015
p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase.
The Journal of biological chemistry
Barrows D,Schoenfeld SM,Hodakoski C,Silkov A,Honig B,Couvillon A,Shymanets A,Nürnberg B,Asara JM,Parsons R
33-9100 was used in immunocytochemistry to investigate how insulin affects Rac1 activation
Fri Nov 27 00:00:00 EST 2015
p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase.
The Journal of biological chemistry
Barrows D,Schoenfeld SM,Hodakoski C,Silkov A,Honig B,Couvillon A,Shymanets A,Nürnberg B,Asara JM,Parsons R
33-9100 was used in immunocytochemistry to investigate how insulin affects Rac1 activation
Fri Nov 27 00:00:00 EST 2015
A potential mode of action for Anakinra in patients with arthrofibrosis following total knee arthroplasty.
Scientific reports
Dixon D,Coates J,del Carpio Pons A,Horabin J,Walker A,Abdul N,Kalson NS,Brewster NT,Weir DJ,Deehan DJ,Mann DA,Borthwick LA
33-9100 was used in immunocytochemistry to determine the role of Anakinra in anthrofibrosis knee patients
Tue Nov 10 00:00:00 EST 2015
Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels.
The Journal of biological chemistry
Fujimura K,Choi S,Wyse M,Strnadel J,Wright T,Klemke R
33-9100 was used in western blot to report that inhibition of eIF5A reduces pancreatic ductal adenocarcinoma cell migration, invasion, and metastasis in vitro and in vivo.
Fri Dec 11 00:00:00 EST 2015
Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells.
Nature protocols
Wong AP,Chin S,Xia S,Garner J,Bear CE,Rossant J
33-9100 was used in western blot to describe a method to generate cystic fibrosis transmembrane conductance regulator protein-expressing airway epithelial cells from human pluripotent stem cells
Sun Mar 01 00:00:00 EST 2015
Glial ankyrins facilitate paranodal axoglial junction assembly.
Nature neuroscience
Chang KJ,Zollinger DR,Susuki K,Sherman DL,Makara MA,Brophy PJ,Cooper EC,Bennett V,Mohler PJ,Rasband MN
33-9100 was used in immunocytochemistry to elucidate the molecular mechanisms underlying paranodal junction assembly
Mon Dec 01 00:00:00 EST 2014
Hantavirus infection with severe proteinuria and podocyte foot-process effacement.
American journal of kidney diseases : the official journal of the National Kidney Foundation
Boehlke C,Hartleben B,Huber TB,Hopfer H,Walz G,Neumann-Haefelin E
33-9100 was used in immunohistochemistry to investigate the effect of Hantavirus infection on podocyte integrity.
Mon Sep 01 00:00:00 EDT 2014
Innate immune factors in the development and maintenance of pouchitis.
Inflammatory bowel diseases
Landy J,Al-Hassi HO,Ronde E,English NR,Mann ER,Bernardo D,Ciclitira PJ,Clark SK,Knight SC,Hart AL
33-9100 was used in flow cytometry to perform longitudinal and cross-sectional studies of patients after restorative proctocolectomy and assess tight junction proteins and dendritic cell characteristics in the ileal pouch
Sat Nov 01 00:00:00 EDT 2014
LMX1B mutation with residual transcriptional activity as a cause of isolated glomerulopathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Isojima T,Harita Y,Furuyama M,Sugawara N,Ishizuka K,Horita S,Kajiho Y,Miura K,Igarashi T,Hattori M,Kitanaka S
33-9100 was used in immunohistochemistry - paraffin section to discuss pathogenesis of nail-patella-like renal disease.
Wed Jan 01 00:00:00 EST 2014
Aberrant cochlear hair cell attachments caused by Nectin-3 deficiency result in hair bundle abnormalities.
Development (Cambridge, England)
Fukuda T,Kominami K,Wang S,Togashi H,Hirata K,Mizoguchi A,Rikitake Y,Takai Y
33-9100 was used in Immunohistochemistry-immunofluorescence to study disturbances to the orientation and morphology of hair bundles, and kinocilium positioning in sensory hair cells of Nectin-3-deficient mice.
Wed Jan 01 00:00:00 EST 2014
Sema6a and Plxna2 mediate spatially regulated repulsion within the developing eye to promote eye vesicle cohesion.
Development (Cambridge, England)
Ebert AM,Childs SJ,Hehr CL,Cechmanek PB,McFarlane S
33-9100 was used in Immunohistochemistry on frozen tissues to propose a tissue-autonomous mechanism of organ cohesion, with neutralization of repulsion promoting interaction between cells within a tissue domain.
Sun Jun 01 00:00:00 EDT 2014
Congenital heart disease protein 5 associates with CASZ1 to maintain myocardial tissue integrity.
Development (Cambridge, England)
Sojka S,Amin NM,Gibbs D,Christine KS,Charpentier MS,Conlon FL
33-9100 was used in immunohistochemistry to investigate the role of cardiac transcription factor CASTOR (CASZ1) in heart development
Fri Aug 01 00:00:00 EDT 2014
A novel dual-flow bioreactor simulates increased fluorescein permeability in epithelial tissue barriers.
Biotechnology journal
Giusti S,Sbrana T,La Marca M,Di Patria V,Martinucci V,Tirella A,Domenici C,Ahluwalia A
33-9100 was used in immunocytochemistry to describe a novel two-chamber modular bioreactor for dynamic in vitro studies of epithelial cells
Mon Sep 01 00:00:00 EDT 2014
Isolation and culture of mouse proepicardium using serum-free conditions.
Methods (San Diego, Calif.)
Garriock RJ,Mikawa T,Yamaguchi TP
33-9100 was used in immunohistochemistry to evaluate an isolation and culture strateg for mouse proepicardium
Tue Apr 01 00:00:00 EDT 2014
Listeria monocytogenes antagonizes the human GTPase Cdc42 to promote bacterial spread.
Cellular microbiology
Rigano LA,Dowd GC,Wang Y,Ireton K
33-9100 was used in immunocytochemistry to test if Cdc42 controls Listeria spread.
Tue Jul 01 00:00:00 EDT 2014
CAR expression in human embryos and hESC illustrates its role in pluripotency and tight junctions.
Reproduction (Cambridge, England)
Krivega M,Geens M,Van de Velde H
33-9100 was used in immunohistochemistry to investigate the role of CAR in pluripotency and tight junctions of human embryos and stem cells.
Sat Nov 01 00:00:00 EDT 2014
Decreased expression of zonula occludens-1 and occludin in the bladder urothelium of patients with interstitial cystitis/painful bladder syndrome.
Journal of the Formosan Medical Association = Taiwan yi zhi
Lee JD,Lee MH
33-9100 was used in immunocytochemistry to study the expression of zonula occludens-1 and occludin in the bladder urothelium of patients with interstitial cystitis/painful bladder syndrome
Wed Jan 01 00:00:00 EST 2014
EGF induces efficient Cx43 gap junction endocytosis in mouse embryonic stem cell colonies via phosphorylation of Ser262, Ser279/282, and Ser368.
FEBS letters
Fong JT,Nimlamool W,Falk MM
33-9100 was used in immunocytochemistry to investigate the effect of EGF on Cx43 gap junction endocytosis in mouse embryonic stem cell colonies and its mechanism
Mon Mar 03 00:00:00 EST 2014
Endothelial cells use dynamic actin to facilitate lymphocyte transendothelial migration and maintain the monolayer barrier.
Molecular biology of the cell
Mooren OL,Li J,Nawas J,Cooper JA
33-9100 was used in immunocytochemistry to investigate the role of the actin cytoskeleton of the endothelium in transmigration
Mon Dec 15 00:00:00 EST 2014
Reconstruction of a seminiferous tubule-like structure in a 3 dimensional culture system of re-aggregated mouse neonatal testicular cells within a collagen matrix.
General and comparative endocrinology
Zhang J,Hatakeyama J,Eto K,Abe S
33-9100 was used in immunohistochemistry to evaluate a 3 dimensional culture system for the reconstruction of a seminiferous tubule-like structure.
Mon Sep 01 00:00:00 EDT 2014
aPKCλ maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface.
Journal of biochemistry
Satoh D,Hirose T,Harita Y,Daimon C,Harada T,Kurihara H,Yamashita A,Ohno S
33-9100 was used in immunohistochemistry (frozen) to study the turnover of intact cell-surface slit diaphragm components.
Fri Aug 01 00:00:00 EDT 2014
p38δ mitogen-activated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes.
Archives of dermatological research
Siljamäki E,Raiko L,Toriseva M,Nissinen L,Näreoja T,Peltonen J,Kähäri VM,Peltonen S
33-9100 was used in immunocytochemistry and western blot to investigate the regulation of ZO-1 by p38delta mitogen-activated protein kinase in differentiating human epidermal keratinocytes
Sat Mar 01 00:00:00 EST 2014
Onset of aquaporin-4 expression in the developing mouse brain.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
Fallier-Becker P,Vollmer JP,Bauer HC,Noell S,Wolburg H,Mack AF
33-9100 was used in immunohistochemistry to study aquaporin-4 expression in the developing mouse brain.
Fri Aug 01 00:00:00 EDT 2014
Sustained Wnt/β-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole.
Nature communications
Herrera A,Saade M,Menendez A,Marti E,Pons S
33-9100 was used in immunohistochemistry and western blot to report that beta-catenin controls the cell fate and polarity of neuroblasts by modulating the expression and localization of aPKC.
Thu Jun 19 00:00:00 EDT 2014
Sustained Wnt/β-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole.
Nature communications
Herrera A,Saade M,Menendez A,Marti E,Pons S
33-9100 was used in immunohistochemistry and western blot to report that beta-catenin controls the cell fate and polarity of neuroblasts by modulating the expression and localization of aPKC.
Thu Jun 19 00:00:00 EDT 2014
Peanut allergens alter intestinal barrier permeability and tight junction localisation in Caco-2 cell cultures.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Price DB,Ackland ML,Burks W,Knight MI,Suphioglu C
33-9100 was used in western blot to investigate the effect of peanut allergens on intestinal barrier permeability and tight junction localisation in Caco-2 cell cultures.
Mon Sep 21 00:00:00 EDT 2015
AmotL2 links VE-cadherin to contractile actin fibres necessary for aortic lumen expansion.
Nature communications
Hultin S,Zheng Y,Mojallal M,Vertuani S,Gentili C,Balland M,Milloud R,Belting HG,Affolter M,Helker CS,Adams RH,Herzog W,Uhlen P,Majumdar A,Holmgren L
33-9100 was used in Immunocytochemistry-immunoflourescence to propose that the VE-cadherin/amotL2 complex links endothelial cells for coordination of cellular morphogenesis for aortic lumen expansion and function.
Wed May 07 00:00:00 EDT 2014
Symmetrical and asymmetrical division analysis provides evidence for a hierarchy of prostate epithelial cell lineages.
Nature communications
Wang J,Zhu HH,Chu M,Liu Y,Zhang C,Liu G,Yang X,Yang R,Gao WQ
33-9100 was used in Immunohistochemistry-immunofluorescence to provide evidence for the existence of a hierarchy of epithelial cell lineages during prostate development, regeneration and tumorigenesis.
Thu Aug 28 00:00:00 EDT 2014
Formation of a polarised primitive endoderm layer in embryoid bodies requires fgfr/erk signalling.
PloS one
Doughton G,Wei J,Tapon N,Welham MJ,Chalmers AD
33-9100 was used in immunocytochemistry to investigate the role of fgfr/erk signalling in the formation of a polarised primitive endoderm layer in embryoid bodies
Wed Jan 14 00:00:00 EST 2015
Estrogen supports urothelial defense mechanisms.
Science translational medicine
Lüthje P,Brauner H,Ramos NL,Ovregaard A,Gläser R,Hirschberg AL,Aspenström P,Brauner A
33-9100 was used in immunohistochemistry (paraffin) to study the effect of estrogen on host-pathogen interactions and the consequences for urinary tract infections.
Wed Jun 19 00:00:00 EDT 2013
Par1b links lumen polarity with LGN-NuMA positioning for distinct epithelial cell division phenotypes.
The Journal of cell biology
Lázaro-Diéguez F,Cohen D,Fernandez D,Hodgson L,van Ijzendoorn SC,Müsch A
33-9100 was used in western blot to show that Parb works with LGN-NuMA to define lumen position and the distinct epithelial division phenotypes.
Mon Oct 28 00:00:00 EDT 2013
Contribution of tight junction proteins to ion, macromolecule, and water barrier in keratinocytes.
The Journal of investigative dermatology
Kirschner N,Rosenthal R,Furuse M,Moll I,Fromm M,Brandner JM
33-9100 was used in immunocytochemistry and western blot to examine the contribution of various tight junction proteins in keratinocytes.
Wed May 01 00:00:00 EDT 2013
ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation.
Development (Cambridge, England)
Herder C,Swiercz JM,Müller C,Peravali R,Quiring R,Offermanns S,Wittbrodt J,Loosli F
33-9100 was used in immunohistochemistry to show that RhoA signaling controls of neuroepithelial apicobasal polarity during vertebrate development.
Mon Jul 01 00:00:00 EDT 2013
Polyphenols protect the epithelial barrier function of Caco-2 cells exposed to indomethacin through the modulation of occludin and zonula occludens-1 expression.
Journal of agricultural and food chemistry
Carrasco-Pozo C,Morales P,Gotteland M
33-9100 was used in immunocytochemistry to assess the protective effect of quercetin, epigallocatechingallate, resveratrol, and rutin against the disruption of epithelial integrity induced by indomethacin.
Wed Jun 05 00:00:00 EDT 2013
Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation.
Journal of cell science
Elsum IA,Martin C,Humbert PO
33-9100 was used in immunocytochemistry and western blot to assess the role of the Scribble polarity module.
Sun Sep 01 00:00:00 EDT 2013
LKB1 controls human bronchial epithelial morphogenesis through p114RhoGEF-dependent RhoA activation.
Molecular and cellular biology
Xu X,Jin D,Durgan J,Hall A
33-9100 was used in immunocytochemistry to report that LKB and p4RhoGEF control RhoA activity to promote apical junction assembly.
Mon Jul 01 00:00:00 EDT 2013
PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus.
Cerebral cortex (New York, N.Y. : 1991)
Shibasaki T,Tokunaga A,Sakamoto R,Sagara H,Noguchi S,Sasaoka T,Yoshida N
33-9100 was used in immunohistochemistry - paraffin section and western blot to study the role of polypyrimidine tract-binding protein in neuronal stem cells in the developing brain.
Thu Aug 01 00:00:00 EDT 2013
Short-chain fatty acids activate AMP-activated protein kinase and ameliorate ethanol-induced intestinal barrier dysfunction in Caco-2 cell monolayers.
The Journal of nutrition
Elamin EE,Masclee AA,Dekker J,Pieters HJ,Jonkers DM
33-9100 was used in immunocytochemistry to analyze the influence of SCFAs and AMP-activated protein kinase on ethanol-induced barrier dysfunction.
Sun Dec 01 00:00:00 EST 2013
Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins.
Journal of tissue engineering and regenerative medicine
Rowland TJ,Blaschke AJ,Buchholz DE,Hikita ST,Johnson LV,Clegg DO
33-9100 was used in immunohistochemistry to test if changes in the extracellular matrix composition improves the frequency of stem cell-RPE differentiation.
Thu Aug 01 00:00:00 EDT 2013
Effect of a two-week treatment with a low dose of 2,2'4,4',5,5'-hexachlorobiphenyl (PCB153) on tight junction protein expression in ovine choroid plexus during long and short photoperiods.
Neurotoxicology and teratology
Szczepkowska A,Lagaraine C,Robert V,Dufourny L,Thiéry JC,Skipor J
33-9100 was used in western blot to examine the photoperiodically different concentration of polychlorinated biphenyls in the cerebrospinal fluid in sheep.
Mon Dec 30 00:00:00 EST 2013
Intercellular Ca(2+) wave propagation in human retinal pigment epithelium cells induced by mechanical stimulation.
Experimental eye research
Abu Khamidakh AE,Juuti-Uusitalo K,Larsson K,Skottman H,Hyttinen J
33-9100 was used in immunocytochemistry to study intercellular calcium communication induced by mechanical stimulation in ARPE-9 cells.
Fri Mar 01 00:00:00 EST 2013
Involvement of PI3K and ROCK signaling pathways in migration of bone marrow-derived mesenchymal stem cells through human brain microvascular endothelial cell monolayers.
Brain research
Lin MN,Shang DS,Sun W,Li B,Xu X,Fang WG,Zhao WD,Cao L,Chen YH
33-9100 was used in immunocytochemistry to study the mechanism underlying mesenchymal stem cells transendothelial migration across the blood brain barrier.
Tue Jun 04 00:00:00 EDT 2013
Helicobacter pylori-induced disruption of monolayer permeability and proinflammatory cytokine secretion in polarized human gastric epithelial cells.
Infection and immunity
Fiorentino M,Ding H,Blanchard TG,Czinn SJ,Sztein MB,Fasano A
33-9100 was used in Immunocytochemistry-immunoflourescence to investigate the ability of Helicobacter pylori to affect permeability and the extent and polarity of the host inflammatory response.
Fri Mar 01 00:00:00 EST 2013
Cultures of astroglial cells derived from brain of adult cichlid fish.
Journal of neuroscience methods
Mack AF,Tiedemann K
33-9100 was used in immunocytochemistry to evaluate a culture system for astroglial cells derived from brain of adult cichlid fish.
Wed Jan 30 00:00:00 EST 2013
Occludin is involved in adhesion, apoptosis, differentiation and Ca2+-homeostasis of human keratinocytes: implications for tumorigenesis.
PloS one
Rachow S,Zorn-Kruppa M,Ohnemus U,Kirschner N,Vidal-y-Sy S,von den Driesch P,Börnchen C,Eberle J,Mildner M,Vettorazzi E,Rosenthal R,Moll I,Brandner JM
33-9100 was used in immunocytochemistry to observe changes in tight junction proteins in various epithelial tumors
Fri Jul 19 00:00:00 EDT 2013
A three-dimensional engineered artery model for in vitro atherosclerosis research.
PloS one
Robert J,Weber B,Frese L,Emmert MY,Schmidt D,von Eckardstein A,Rohrer L,Hoerstrup SP
33-9100 was used in immunohistochemistry (frozen) to generate and characterize a 3D tissue engineered artery.
Tue Aug 12 00:00:00 EDT 2014
Differential expression of junctional adhesion molecules in different stages of systemic sclerosis.
Arthritis and rheumatism
Manetti M,Guiducci S,Romano E,Rosa I,Ceccarelli C,Mello T,Milia AF,Conforti ML,Ibba-Manneschi L,Matucci-Cerinic M
33-9100 was used in Immunocytochemistry to investigate the possible role of junctional adhesion molecules in systemic sclerosis pathogenesis.
Tue Jan 01 00:00:00 EST 2013
Norovirus binding to intestinal epithelial cells is independent of histo-blood group antigens.
PloS one
Murakami K,Kurihara C,Oka T,Shimoike T,Fujii Y,Takai-Todaka R,Park Y,Wakita T,Matsuda T,Hokari R,Miura S,Katayama K
33-9100 was used in immunocytochemistry to test if norovirus utilizes histo-blood group antigens for internalization
Thu Jan 30 00:00:00 EST 2014
Oncogenic transformation of mammary epithelial cells by transforming growth factor beta independent of mammary stem cell regulation.
Cancer cell international
Dunphy KA,Seo JH,Kim DJ,Roberts AL,Tao L,DiRenzo J,Balboni AL,Crisi GM,Hagen MJ,Chandrasekaran T,Gauger KJ,Schneider SS,Jerry DJ
33-9100 was used in immunocytochemistry to study the effect of transient exposure to TGFβ during involution and determine the persistent effects on premalignant mammary epithelium.
Tue May 20 00:00:00 EDT 2014
Generation of functional thyroid from embryonic stem cells.
Nature
Antonica F,Kasprzyk DF,Opitz R,Iacovino M,Liao XH,Dumitrescu AM,Refetoff S,Peremans K,Manto M,Kyba M,Costagliola S
33-9100 was used in immunocytochemistry to report that mouse embryonic stem cells can be used to generate functional thyroid tissue.
Thu Nov 01 00:00:00 EDT 2012
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.
Nature
Bell RD,Winkler EA,Singh I,Sagare AP,Deane R,Wu Z,Holtzman DM,Betsholtz C,Armulik A,Sallstrom J,Berk BC,Zlokovic BV
Wed May 16 00:00:00 EDT 2012
Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis.
Cancer cell
Iden S,van Riel WE,Schäfer R,Song JY,Hirose T,Ohno S,Collard JG
33-9100 was used in immunocytochemistry to identify a dual function of Par3 in skin cancer.
Tue Sep 11 00:00:00 EDT 2012
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses.
Nature neuroscience
Shi Y,Kirwan P,Smith J,Robinson HP,Livesey FJ
33-9100 was used in immunocytochemistry to develop a process for human cortical development using pluripotent stem cells.
Sun Feb 05 00:00:00 EST 2012
Short-term feedback regulation of bile salt uptake by bile salts in rodent liver.
Hepatology (Baltimore, Md.)
Mühlfeld S,Domanova O,Berlage T,Stross C,Helmer A,Keitel V,Häussinger D,Kubitz R
33-9100 was used in immunohistochemistry (frozen) to study the regulation of Ntcp by primary bile salts in vivo.
Sat Dec 01 00:00:00 EST 2012
In vitro culture of epicardial cells from adult zebrafish heart on a fibrin matrix.
Nature protocols
Kim J,Rubin N,Huang Y,Tuan TL,Lien CL
33-9100 was used in immunocytochemistry to describe a method to culture epicardial cells from adult zebrafish hearts.
Thu Jan 19 00:00:00 EST 2012
Generation of hESC-derived retinal pigment epithelium on biopolymer coated polyimide membranes.
Biomaterials
Subrizi A,Hiidenmaa H,Ilmarinen T,Nymark S,Dubruel P,Uusitalo H,Yliperttula M,Urtti A,Skottman H
33-9100 was used in immunocytochemistry to report that a polyimide biomembrane is a suitable scaffold for generating retinal pigment epithelium from human embryonic stem cells.
Thu Nov 01 00:00:00 EDT 2012
Claudin k is specifically expressed in cells that form myelin during development of the nervous system and regeneration of the optic nerve in adult zebrafish.
Glia
Münzel EJ,Schaefer K,Obirei B,Kremmer E,Burton EA,Kuscha V,Becker CG,Brösamle C,Williams A,Becker T
33-9100 was used in immunohistochemistry (frozen) to use claudin k antibodies and claudin k:GFP reporter line to visualize oligodendrocyte and Schwann cell differentiation in vivo.
Wed Feb 01 00:00:00 EST 2012
ETV5 transcription factor is overexpressed in ovarian cancer and regulates cell adhesion in ovarian cancer cells.
International journal of cancer
Llauradó M,Abal M,Castellví J,Cabrera S,Gil-Moreno A,Pérez-Benavente A,Colás E,Doll A,Dolcet X,Matias-Guiu X,Vazquez-Levin M,Reventós J,Ruiz A
33-9100 was used in immunocytochemistry to study the role of ETV5 in epithelial ovarian cancer.
Sun Apr 01 00:00:00 EDT 2012
ROCK1-directed basement membrane positioning coordinates epithelial tissue polarity.
Development (Cambridge, England)
Daley WP,Gervais EM,Centanni SW,Gulfo KM,Nelson DA,Larsen M
33-9100 was used in Immunocytochemistry to indicate that ROCK1/PAR-1b-dependent regulation of basement membrane placement is required for the coordination of tissue polarity and the elaboration of tissue structure in the developing submandibular salivary gland.
Sun Jan 01 00:00:00 EST 2012
Motoneuronal Sema3C is essential for setting stereotyped motor tract positioning in limb-derived chemotropic semaphorins.
Development (Cambridge, England)
Sanyas I,Bozon M,Moret F,Castellani V
33-9100 was used in immunohistochemistry (frozen) to describe a novel mechanism by which ligand/receptor co-expression in neurons modulates the integration of other guidance cues by the growth cone.
Mon Oct 01 00:00:00 EDT 2012
Human intestinal epithelial cells exhibit a cellular response indicating a potential toxicity upon exposure to hematite nanoparticles.
Cell biology and toxicology
Kalive M,Zhang W,Chen Y,Capco DG
33-9100 was used in immunocytochemistry to assess the effects of different-sized nanoparticles on intestinal epithelia cytotoxicity.
Mon Oct 01 00:00:00 EDT 2012
Regulation of CXCL8/IL-8 expression by zonula occludens-1 in human breast cancer cells.
Molecular cancer research : MCR
Brysse A,Mestdagt M,Polette M,Luczka E,Hunziker W,Noël A,Birembaut P,Foidart JM,Gilles C
33-9100 was used in immunocytochemistry and western blot to examine the influence of ZO-1 on chemokines expression in breast cancer cells.
Sun Jan 01 00:00:00 EST 2012
Characterization of protocadherin-1 expression in primary bronchial epithelial cells: association with epithelial cell differentiation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Koning H,Sayers I,Stewart CE,de Jong D,Ten Hacken NH,Postma DS,van Oosterhout AJ,Nawijn MC,Koppelman GH
33-9100 was used in western blot to determine regulation of PCDH during mucociliary differentiation.
Sun Jan 01 00:00:00 EST 2012
NHERF1 and CFTR restore tight junction organisation and function in cystic fibrosis airway epithelial cells: role of ezrin and the RhoA/ROCK pathway.
Laboratory investigation; a journal of technical methods and pathology
Castellani S,Guerra L,Favia M,Di Gioia S,Casavola V,Conese M
33-9100 was used in western blot to test if NHERF1 and CFTR are involved in the organization and function of tight junctions.
Thu Nov 01 00:00:00 EDT 2012
Tight junction proteins expression and modulation in immune cells and multiple sclerosis.
Journal of cellular and molecular medicine
Mandel I,Paperna T,Glass-Marmor L,Volkowich A,Badarny S,Schwartz I,Vardi P,Koren I,Miller A
33-9100 was used in immunocytochemistry to examine the function and location of tight junction proteins in immune cells.
Sun Apr 01 00:00:00 EDT 2012
Flow mechanotransduction regulates traction forces, intercellular forces, and adherens junctions.
American journal of physiology. Heart and circulatory physiology
Ting LH,Jahn JR,Jung JI,Shuman BR,Feghhi S,Han SJ,Rodriguez ML,Sniadecki NJ
33-9100 was used in immunocytochemistry to examine the relationships among traction forces, intercellular forces, and cell-cell junctions in endothelial cells.
Fri Jun 01 00:00:00 EDT 2012
Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death.
Investigative ophthalmology & visual science
Cammas L,Wolfe J,Choi SY,Dedhar S,Beggs HE
33-9100 was used in immunohistochemistry (paraffin) to determine the function of integrin-linked kinase in the mouse lens.
Thu May 17 00:00:00 EDT 2012
Effects of proinflammatory cytokines on the claudin-19 rich tight junctions of human retinal pigment epithelium.
Investigative ophthalmology & visual science
Peng S,Gan G,Rao VS,Adelman RA,Rizzolo LJ
Fri Jul 27 00:00:00 EDT 2012
Effects of proinflammatory cytokines on the claudin-19 rich tight junctions of human retinal pigment epithelium.
Investigative ophthalmology & visual science
Peng S,Gan G,Rao VS,Adelman RA,Rizzolo LJ
Fri Jul 27 00:00:00 EDT 2012
Loss of N-cadherin from the endothelium causes stromal edema and epithelial dysgenesis in the mouse cornea.
Investigative ophthalmology & visual science
Vassilev VS,Mandai M,Yonemura S,Takeichi M
33-9100 was used in immunohistochemistry to examine the role of N-cadherin in maintaining proper architecture and function of corneal endothelium.
Wed Oct 17 00:00:00 EDT 2012
Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding Ca(2+) /Mn(2+) ATPase SPCA1 in cultured keratinocytes.
Experimental dermatology
Raiko L,Siljamäki E,Mahoney MG,Putaala H,Suominen E,Peltonen J,Peltonen S
33-9100 was used in immunocytochemistry and western blot to develop and characterize a model for Hailey-Hailey disease using normal keratinocytes.
Wed Aug 01 00:00:00 EDT 2012
Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding Ca(2+) /Mn(2+) ATPase SPCA1 in cultured keratinocytes.
Experimental dermatology
Raiko L,Siljamäki E,Mahoney MG,Putaala H,Suominen E,Peltonen J,Peltonen S
33-9100 was used in immunocytochemistry and western blot to develop and characterize a model for Hailey-Hailey disease using normal keratinocytes.
Wed Aug 01 00:00:00 EDT 2012
A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells.
Toxicology and applied pharmacology
Sarró E,Jacobs-Cachá C,Itarte E,Meseguer A
33-9100 was used in western blot to identify new targets to prevent cyclosporine A-induced toxicity in proximal tubule cells.
Sun Jan 15 00:00:00 EST 2012
3D single molecule tracking with multifocal plane microscopy reveals rapid intercellular transferrin transport at epithelial cell barriers.
Biophysical journal
Ram S,Kim D,Ober RJ,Ward ES
33-9100 was used in Immunocytochemistry-immunoflourescence to reveal the complexity of the 3D trafficking pathways in epithelial cell barriers.
Wed Oct 03 00:00:00 EDT 2012
Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function.
Infection and immunity
Langer M,Duggan ES,Booth JL,Patel VI,Zander RA,Silasi-Mansat R,Ramani V,Veres TZ,Prenzler F,Sewald K,Williams DM,Coggeshall KM,Awasthi S,Lupu F,Burian D,Ballard JD,Braun A,Metcalf JP
33-9100 was used in immunocytochemistry and western blot to report that lethal toxin targets alveolar epithelial cells.
Sat Dec 01 00:00:00 EST 2012
Neural tube defects by NUAK1 and NUAK2 double mutation.
Developmental dynamics : an official publication of the American Association of Anatomists
Ohmura T,Shioi G,Hirano M,Aizawa S
33-9100 was used in immunohistochemistry (paraffin) to elucidate the function of NUAK1 and NUAK2 in neurulation.
Wed Aug 01 00:00:00 EDT 2012
Characterization of Pax2 expression in the goldfish optic nerve head during retina regeneration.
PloS one
Parrilla M,Lillo C,Herrero-Turrión MJ,Arévalo R,Aijón J,Lara JM,Velasco A
33-9100 was used in immunohistochemistry to study pax2a in the optic nerve head of goldfish
Mon Aug 27 00:00:00 EDT 2012
GLP-2 enhances barrier formation and attenuates TNFα-induced changes in a Caco-2 cell model of the intestinal barrier.
Regulatory peptides
Moran GW,O'Neill C,McLaughlin JT
33-9100 was used in western blot to test if GLP-2 regulates tight junctions.
Wed Oct 10 00:00:00 EDT 2012
Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia.
Molecular neurodegeneration
Cui J,Chen S,Zhang C,Meng F,Wu W,Hu R,Hadass O,Lehmidi T,Blair GJ,Lee M,Chang M,Mobashery S,Sun GY,Gu Z
33-9100 was used in Immunohistochemistry to assess the effects of SB-3CT on the neurovasculature.
Tue May 15 00:00:00 EDT 2012
Toll-like receptor responses of normal human urothelial cells to bacterial flagellin and lipopolysaccharide.
The Journal of urology
Smith NJ,Varley CL,Eardley I,Feather S,Trejdosiewicz LK,Southgate J
33-9100 was used in immunocytochemistry to study toll-like receptor expression and responses in normal human urothelium.
Thu Sep 01 00:00:00 EDT 2011
Tissue engineering potential of urothelial cells from diseased bladders.
The Journal of urology
Subramaniam R,Hinley J,Stahlschmidt J,Southgate J
33-9100 was used in immunohistochemistry to assess the suitability of urothelium from patients with abnormal bladders for use in surgical reconstruction.
Tue Nov 01 00:00:00 EDT 2011
CD44 regulates tight-junction assembly and barrier function.
The Journal of investigative dermatology
Kirschner N,Haftek M,Niessen CM,Behne MJ,Furuse M,Moll I,Brandner JM
Fri Apr 01 00:00:00 EDT 2011
CD44 regulates tight-junction assembly and barrier function.
The Journal of investigative dermatology
Kirschner N,Haftek M,Niessen CM,Behne MJ,Furuse M,Moll I,Brandner JM
Fri Apr 01 00:00:00 EDT 2011
Adenosine receptor signaling modulates permeability of the blood-brain barrier.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Carman AJ,Mills JH,Krenz A,Kim DG,Bynoe MS
33-9100 was used in immunocytochemistry to show that adenosine receptor signaling modulates blood brain barrier permeability in vivo.
Wed Sep 14 00:00:00 EDT 2011
Relocalization of cell adhesion molecules during neoplastic transformation of human fibroblasts.
International journal of oncology
Belgiovine C,Chiodi I,Mondello C
33-9100 was used in western blot to investigate neoplastic transformation of telomerase in immortalized human fibroblasts.
Tue Nov 01 00:00:00 EDT 2011
Effects of calcium oxalate monohydrate crystals on expression and function of tight junction of renal tubular epithelial cells.
Laboratory investigation; a journal of technical methods and pathology
Peerapen P,Thongboonkerd V
Sat Jan 01 00:00:00 EST 2011
Effects of calcium oxalate monohydrate crystals on expression and function of tight junction of renal tubular epithelial cells.
Laboratory investigation; a journal of technical methods and pathology
Peerapen P,Thongboonkerd V
Sat Jan 01 00:00:00 EST 2011
Kv7.1 surface expression is regulated by epithelial cell polarization.
American journal of physiology. Cell physiology
Andersen MN,Olesen SP,Rasmussen HB
33-9100 was used in immunocytochemistry to examine the localization and distribution of K(V)7.1 during the calcium switch.
Fri Apr 01 00:00:00 EDT 2011
Corticosteroid regulation of P-glycoprotein in the developing blood-brain barrier.
Endocrinology
Iqbal M,Gibb W,Matthews SG
33-9100 was used in immunocytochemistry to examine the role of cortisol and dexamethasone in the up-regulation of fetal brain microvessel P-gp expression.
Tue Mar 01 00:00:00 EST 2011
Glomerular expression of kidney injury molecule-1 and podocytopenia in diabetic glomerulopathy.
American journal of nephrology
Zhao X,Zhang Y,Li L,Mann D,Imig JD,Emmett N,Gibbons G,Jin LM
33-9100 was used in Immunocytochemistry to show that glomerular KIM-1 expression was increased, in proportion to the extent of proteinuria and podocytopenia in the diabetic animals, supporting that KIM-1 could be used as a potential biomarker for glomerular injury in proteinuric kidney disease.
Wed Jan 25 00:00:00 EST 2012
Matrigel improves functional properties of primary human salivary gland cells.
Tissue engineering. Part A
Maria OM,Zeitouni A,Gologan O,Tran SD
33-9100 was used in immunohistochemistry to characterize a graft source from human salivary glands.
Sun May 01 00:00:00 EDT 2011
A novel gelatin hydrogel carrier sheet for corneal endothelial transplantation.
Tissue engineering. Part A
Watanabe R,Hayashi R,Kimura Y,Tanaka Y,Kageyama T,Hara S,Tabata Y,Nishida K
33-9100 was used in immunocytochemistry to describe a method to cultivate corneal endothelial cells for transplantation.
Thu Sep 01 00:00:00 EDT 2011
Tight junction proteins vary in the choroid plexus of ewes according to photoperiod.
Brain research
Lagaraine C,Skipor J,Szczepkowska A,Dufourny L,Thiery JC
33-9100 was used in western blot to compare the tight junction proteins in the choroid plexus of ewes exposed to short or long days.
Wed Jun 01 00:00:00 EDT 2011
Roles of mitogen-activated protein kinases in the modulation of endothelial cell function following thermal injury.
Shock (Augusta, Ga.)
Wu W,Huang Q,He F,Xiao M,Pang S,Guo X,Brunk UT,Zhao K,Zhao M
33-9100 was used in immunocytochemistry to investigate how the different mitogen-activated protein kinases contribute to healing after burn injury using various chemical inhibitors.
Wed Jun 01 00:00:00 EDT 2011
Low abundance of sweat duct Cl- channel CFTR in both healthy and cystic fibrosis athletes with exceptionally salty sweat during exercise.
American journal of physiology. Regulatory, integrative and comparative physiology
Brown MB,Haack KK,Pollack BP,Millard-Stafford M,McCarty NA
33-9100 was used in Immunohistochemistry-immunofluorescence to examine the mechanisms underlying interindividual variability in human sweat sodium concentration.
Tue Mar 01 00:00:00 EST 2011
Localization of AQP5 during development of the mouse submandibular salivary gland.
Journal of molecular histology
Larsen HS,Aure MH,Peters SB,Larsen M,Messelt EB,Kanli Galtung H
33-9100 was used in immunohistochemistry - paraffin section to study the temporal-spatial distribution of aquaporin 5 during submandibular gland development.
Tue Feb 01 00:00:00 EST 2011
Wnt/β-catenin dependent cell proliferation underlies segmented lateral line morphogenesis.
Developmental biology
Aman A,Nguyen M,Piotrowski T
33-9100 was used in immunohistochemistry to report that Wnt/beta-catenin signaling in the leading zone of the primordium plays an important role in orchestrating lateral line morphogenesis
Sat Jan 15 00:00:00 EST 2011
Subcellular distribution of connexin45 in OFF bipolar cells of the mouse retina.
The Journal of comparative neurology
Hilgen G,von Maltzahn J,Willecke K,Weiler R,Dedek K
33-9100 was used in western blot to investigate the localization and function of Cx45 in OFF bipolar cells.
Tue Feb 15 00:00:00 EST 2011
Selection for EGFR gene amplification in a breast epithelial cell line with basal-like phenotype and hereditary background.
In vitro cellular & developmental biology. Animal
Ingthorsson S,Halldorsson T,Sigurdsson V,Friðriksdottir AJ,Bodvarsdottir SK,Steinarsdottir M,Johannsson O,Magnusson MK,Ogmundsdottir HM,Gudjonsson T
33-9100 was used in immunocytochemistry to establish and characterize an epithelial cell line derived from a breast carcinoma from a patient with a strong family history of breast cancer but no known breast cancer susceptibility mutation
Tue Feb 01 00:00:00 EST 2011
Comparison of tight junction protein expression in the ciliary epithelia of mouse, rabbit, cat and human eyes.
Biotechnic & histochemistry : official publication of the Biological Stain Commission
Karim MJ,Biswas S,Bhattacherjee P,Paterson CA
33-9100 was used in immunohistochemistry to investigate if the expression pattern of tight junction proteins in mice, rabbits, and cats resemble those of humans
Wed Jun 01 00:00:00 EDT 2011
Retinal degeneration progression changes lentiviral vector cell targeting in the retina.
PloS one
Calame M,Cachafeiro M,Philippe S,Schouwey K,Tekaya M,Wanner D,Sarkis C,Kostic C,Arsenijevic Y
33-9100 was used in immunohistochemistry to examine the tropism of a lentiviral vector in the degenerating retina of mice.
Fri Apr 13 00:00:00 EDT 2012
Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias.
Oncotarget
Schneckenleithner C,Bago-Horvath Z,Dolznig H,Neugebauer N,Kollmann K,Kolbe T,Decker T,Kerjaschki D,Wagner KU,Müller M,Stoiber D,Sexl V
33-9100 was used in immunocytochemistry to characterize mammary cancers in multiparous Stat1 knockout mice
Thu Dec 01 00:00:00 EST 2011
Osmotic pressure-adaptive responses in the eye tissues of rainbow smelt (Osmerus mordax).
Molecular vision
Gendron RL,Armstrong E,Paradis H,Haines L,Desjardins M,Short CE,Clow KA,Driedzic WR
33-9100 was used in immunohistochemistry to study the osmotic adaptation of the rainbow smelt eye.
Fri Feb 10 00:00:00 EST 2012
A MicroRNA targeting dicer for metastasis control.
Cell
Martello G,Rosato A,Ferrari F,Manfrin A,Cordenonsi M,Dupont S,Enzo E,Guzzardo V,Rondina M,Spruce T,Parenti AR,Daidone MG,Bicciato S,Piccolo S
33-9100 was used in immunocytochemistry to show that miR-103/107 reduces miRNA biosynthesis by targeting Dicer
Fri Jun 25 00:00:00 EDT 2010
OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling.
Nature neuroscience
Fietz SA,Kelava I,Vogt J,Wilsch-Bräuninger M,Stenzel D,Fish JL,Corbeil D,Riehn A,Distler W,Nitsch R,Huttner WB
33-9100 was used in immunohistochemistry - paraffin section to characterize progenitors in the outer subventricular zone
Tue Jun 01 00:00:00 EDT 2010
The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
Cancer research
Liu M,Sakamaki T,Casimiro MC,Willmarth NE,Quong AA,Ju X,Ojeifo J,Jiao X,Yeow WS,Katiyar S,Shirley LA,Joyce D,Lisanti MP,Albanese C,Pestell RG
33-9100 was used in western blot to determine the role of mammary epithelial cell NF-kapaB signaling in tumor progression in vivo.
Wed Dec 15 00:00:00 EST 2010
The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
Cancer research
Liu M,Sakamaki T,Casimiro MC,Willmarth NE,Quong AA,Ju X,Ojeifo J,Jiao X,Yeow WS,Katiyar S,Shirley LA,Joyce D,Lisanti MP,Albanese C,Pestell RG
33-9100 was used in western blot to determine the role of mammary epithelial cell NF-kapaB signaling in tumor progression in vivo.
Wed Dec 15 00:00:00 EST 2010
Multipotent mesenchymal stem cells from human placenta: critical parameters for isolation and maintenance of stemness after isolation.
American journal of obstetrics and gynecology
Semenov OV,Koestenbauer S,Riegel M,Zech N,Zimmermann R,Zisch AH,Malek A
33-9100 was used in flow cytometry to isolate and characterize multipotent mesenchymal stem cells from term human placenta
Mon Feb 01 00:00:00 EST 2010
Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes.
Diabetes
Leal EC,Martins J,Voabil P,Liberal J,Chiavaroli C,Bauer J,Cunha-Vaz J,Ambrósio AF
Fri Oct 01 00:00:00 EDT 2010
Fhit regulates invasion of lung tumor cells.
Oncogene
Joannes A,Bonnomet A,Bindels S,Polette M,Gilles C,Burlet H,Cutrona J,Zahm JM,Birembaut P,Nawrocki-Raby B
33-9100 was used in immunocytochemistry and western blot to examine the role of Fhit during tumor cell invasion
Thu Feb 25 00:00:00 EST 2010
Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II.
Development (Cambridge, England)
Hirota Y,Meunier A,Huang S,Shimozawa T,Yamada O,Kida YS,Inoue M,Ito T,Kato H,Sakaguchi M,Sunabori T,Nakaya MA,Nonaka S,Ogura T,Higuchi H,Okano H,Spassky N,Sawamoto K
33-9100 was used in immunohistochemistry to investigate the cellular and molecular mechanisms by which ependymal cells establish polarity
Wed Sep 01 00:00:00 EDT 2010
Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers.
The Journal of physiology
LeSimple P,Liao J,Robert R,Gruenert DC,Hanrahan JW
33-9100 was used in immunocytochemistry to elucidate the role of cystic fibrosis transmembrane conductance regulator in epithelial tightness
Thu Apr 15 00:00:00 EDT 2010
Trafficking and recycling of the connexin43 gap junction protein during mitosis.
Traffic (Copenhagen, Denmark)
Boassa D,Solan JL,Papas A,Thornton P,Lampe PD,Sosinsky GE
33-9100 was used in western blot to determine Cx43 distributions during mitosis in endogenous and exogenous expressing cells
Mon Nov 01 00:00:00 EDT 2010
A novel method of culturing human oral mucosal epithelial cell sheet using post-mitotic human dermal fibroblast feeder cells and modified keratinocyte culture medium for ocular surface reconstruction.
The British journal of ophthalmology
Oie Y,Hayashi R,Takagi R,Yamato M,Takayanagi H,Tano Y,Nishida K
33-9100 was used in immunocytochemistry to discuss culturing conditions of cells used for ocular surface reconstruction
Wed Sep 01 00:00:00 EDT 2010
Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Ponsaerts R,De Vuyst E,Retamal M,D'hondt C,Vermeire D,Wang N,De Smedt H,Zimmermann P,Himpens B,Vereecke J,Leybaert L,Bultynck G
33-9100 was used in western blot to elucidate the mechanisms that regulate connexin-hemichannel activity
Mon Nov 01 00:00:00 EDT 2010
Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy.
The American journal of pathology
Nakatsukasa M,Kawasaki S,Yamasaki K,Fukuoka H,Matsuda A,Tsujikawa M,Tanioka H,Nagata-Takaoka M,Hamuro J,Kinoshita S
33-9100 was used in immunocytochemistry, immunohistochemistry, and western blot to determine the relationship between the TACSTD2 gene and epithelial barrier function
Wed Sep 01 00:00:00 EDT 2010
Expression of semaphorin 3A in the rat corneal epithelium during wound healing.
Biochemical and biophysical research communications
Morishige N,Ko JA,Morita Y,Nishida T
33-9100 was used in immunohistochemistry - frozen section and western blot to study the expression and localization of Sema3A during corneal epithelial wound healing
Fri May 14 00:00:00 EDT 2010
Validation system of tissue-engineered epithelial cell sheets for corneal regenerative medicine.
Tissue engineering. Part C, Methods
Hayashi R,Yamato M,Takayanagi H,Oie Y,Kubota A,Hori Y,Okano T,Nishida K
33-9100 was used in immunohistochemistry - frozen section to report a validation system for cultivated epithelial cell sheets
Sun Aug 01 00:00:00 EDT 2010
Astroglial structures in the zebrafish brain.
The Journal of comparative neurology
Grupp L,Wolburg H,Mack AF
33-9100 was used in immunohistochemistry to investigate astroglial structures in zebrafish.
Mon Nov 01 00:00:00 EDT 2010
Visualization of transepithelial passage of the immunogenic 33-residue peptide from alpha-2 gliadin in gluten-sensitive macaques.
PloS one
Mazumdar K,Alvarez X,Borda JT,Dufour J,Martin E,Bethune MT,Khosla C,Sestak K
33-9100 was used in immunocytochemistry to establish a rhesus macaque model of gluten sensitivity
Mon Apr 19 00:00:00 EDT 2010
Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown.
PloS one
Haarmann A,Deiss A,Prochaska J,Foerch C,Weksler B,Romero I,Couraud PO,Stoll G,Rieckmann P,Buttmann M
33-9100 was used in immunocytochemistry to determine the regulation of JAM-A expression in brain endothelial cells and evaluate sJAM-A as a biomarker of blood-brain barrier function
Thu Oct 21 00:00:00 EDT 2010
FGF signalling during embryo development regulates cilia length in diverse epithelia.
Nature
Neugebauer JM,Amack JD,Peterson AG,Bisgrove BW,Yost HJ
33-9100 was used in immunocytochemistry to report that fibroblast growth factor signaling regulates cilia length and function in diverse epithelia during zebrafish and Xenopus development
Thu Apr 02 00:00:00 EDT 2009
The bacterial virulence factor InlC perturbs apical cell junctions and promotes cell-to-cell spread of Listeria.
Nature cell biology
Rajabian T,Gavicherla B,Heisig M,Müller-Altrock S,Goebel W,Gray-Owen SD,Ireton K
33-9100 was used in immunocytochemistry to identify Listeria monocytogenes and host proteins that directly regulate protrusions
Thu Oct 01 00:00:00 EDT 2009
Expression and localisation of aquaporin water channels in human urothelium in situ and in vitro.
European urology
Rubenwolf PC,Georgopoulos NT,Clements LA,Feather S,Holland P,Thomas DF,Southgate J
33-9100 was used in immunocytochemistry to test if human urothelium expresses functional aquaporin water channels
Tue Dec 01 00:00:00 EST 2009
Foxa2 regulates polarity and epithelialization in the endoderm germ layer of the mouse embryo.
Development (Cambridge, England)
Burtscher I,Lickert H
33-9100 was used in immunohistochemistry to investigate germ-layer formation in mice
Sun Mar 01 00:00:00 EST 2009
Large-scale proteomic analysis of tyrosine-phosphorylation induced by T-cell receptor or B-cell receptor activation reveals new signaling pathways.
Proteomics
Matsumoto M,Oyamada K,Takahashi H,Sato T,Hatakeyama S,Nakayama KI
33-9100 was used in immunoprecipitation and western blot to measure tyrosine-phosphorylated proteins abundance in T cell, B cells, and nonlymphoid cells
Wed Jul 01 00:00:00 EDT 2009
Functional suppression of E-cadherin by protein kinase Cdelta.
Journal of cell science
Chen CL,Chen HC
33-9100 was used in Immunocytochemistry to study the effect of green fluorescent protein-protein kinase C delta and GFP-PKCalpha on cell-cell junctions of Madin Darby canine kidney cells.
Sun Feb 15 00:00:00 EST 2009
Novel sutureless keratoplasty with a chemically defined bioadhesive.
Investigative ophthalmology & visual science
Takaoka M,Nakamura T,Sugai H,Bentley AJ,Nakajima N,Yokoi N,Fullwood NJ,Hyon SH,Kinoshita S
33-9100 was used in immunohistochemistry - frozen section to assess sutureless keratoplasty using a chemically-defined bioadhesive made from food or medical additives
Mon Jun 01 00:00:00 EDT 2009
Barrier function of cultivated limbal and oral mucosal epithelial cell sheets.
Investigative ophthalmology & visual science
Shimazaki J,Higa K,Kato N,Satake Y
33-9100 was used in immunohistochemistry - frozen section to observe the barrier function of cultivated limbal and oral mucosal epithelial sheets
Tue Dec 01 00:00:00 EST 2009
Transepithelial fluxes of adenosine and 2'-deoxyadenosine across human renal proximal tubule cells: roles of nucleoside transporters hENT1, hENT2, and hCNT3.
American journal of physiology. Renal physiology
Elwi AN,Damaraju VL,Kuzma ML,Mowles DA,Baldwin SA,Young JD,Sawyer MB,Cass CE
33-9100 was used in immunocytochemistry to ascertain the roles of human nucleoside transporters in mediating transepithelial fluxes of adenosine, 2'-deoxyadenosine, and three purine nucleoside anti-cancer drugs
Mon Jun 01 00:00:00 EDT 2009
Mechanisms of defence from Fe(II) toxicity in human intestinal Caco-2 cells.
Toxicology in vitro : an international journal published in association with BIBRA
Natoli M,Felsani A,Ferruzza S,Sambuy Y,Canali R,Scarino ML
33-9100 was used in immunocytochemistry to examine iron-associated toxicity in intestinal epithelial cells
Tue Dec 01 00:00:00 EST 2009
CFTR expression but not Cl- transport is involved in the stimulatory effect of bile acids on apical Cl-/HCO3- exchange activity in human pancreatic duct cells.
Pancreas
Ignáth I,Hegyi P,Venglovecz V,Székely CA,Carr G,Hasegawa M,Inoue M,Takács T,Argent BE,Gray MA,Rakonczay Z
33-9100 was used in immunocytochemistry to analyze the effects of chenodeoxycholate on human pancreatic duct cells
Sun Nov 01 00:00:00 EDT 2009
Phosphatidylinositol 3'-kinase signalling supports cell height in established epithelial monolayers.
Journal of molecular histology
Jeanes A,Smutny M,Leerberg JM,Yap AS
33-9100 was used in immunocytochemistry to investigate the role of PI3-kinase in cultured epithelia
Thu Oct 01 00:00:00 EDT 2009
A cell polarity protein aPKClambda is required for eye lens formation and growth.
Developmental biology
Sugiyama Y,Akimoto K,Robinson ML,Ohno S,Quinlan RA
33-9100 was used in immunohistochemistry - paraffin section to report a role for aPKClambda in the development of the lens fulcrum
Tue Dec 15 00:00:00 EST 2009
Effects of di(2-ethylhexyl) phthalate on gap and tight junction protein expression in the testis of prepubertal rats.
Microscopy research and technique
Sobarzo CM,Lustig L,Ponzio R,Suescun MO,Denduchis B
33-9100 was used in immunohistochemistry - frozen section and western blot to test if di(2-ethylhexyl) phthalate alters the expression of testicular gap and tight junction proteins
Sun Nov 01 00:00:00 EDT 2009
Apical polarity protein PrkCi is necessary for maintenance of spinal cord precursors in zebrafish.
Developmental dynamics : an official publication of the American Association of Anatomists
Roberts RK,Appel B
33-9100 was used in immunocytochemistry to investigate the role of protein kinase C in the orientation of zebrafish spinal cord precursors
Wed Jul 01 00:00:00 EDT 2009
Sequence- or position-specific mutations in the carboxyl-terminal FL motif of the kidney sodium bicarbonate cotransporter (NBC1) disrupt its basolateral targeting and alpha-helical structure.
The Journal of membrane biology
Li HC,Collier JH,Shawki A,Rudra JS,Li EY,Mackenzie B,Soleimani M
33-9100 was used in immunocytochemistry to characterize the dihydrophobic FL motif of NBC1
Sun Mar 01 00:00:00 EST 2009
Voltage-gated sodium channels in taste bud cells.
BMC neuroscience
Gao N,Lu M,Echeverri F,Laita B,Kalabat D,Williams ME,Hevezi P,Zlotnik A,Moyer BD
33-9100 was used in Immunofluorescence in immunohistochemistry on frozen tissues to study the molecular and histological expression profiles of cation channels involved in electrical signal transmission from apical to basolateral membrane domains in taste bud cells.
Thu Mar 12 00:00:00 EDT 2009
Tight junctions in Hailey-Hailey and Darier's diseases.
Dermatology reports
Raiko L,Leinonen P,Hägg PM,Peltonen J,Oikarinen A,Peltonen S
33-9100 was used in immunohistochemistry (frozen) to study the expression and dynamics of the tight junction proteins during the disruption of desmosomes in Hailey-Hailey disease and Darier's disease lesions.
Mon Nov 16 00:00:00 EST 2009
Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis.
Nature cell biology
Konno D,Shioi G,Shitamukai A,Mori A,Kiyonari H,Miyata T,Matsuzaki F
33-9100 was used in immunohistochemistry - frozen section to assess if spindle orientation control maintains neuroepithelial cell populations and affects cell proliferation or differentiation
Tue Jan 01 00:00:00 EST 2008
Generation of a functional, differentiated porcine urothelial tissue in vitro.
European urology
Turner AM,Subramaniam R,Thomas DF,Southgate J
33-9100 was used in immunohistochemistry to discuss differentiation of the urothelium
Mon Dec 01 00:00:00 EST 2008
Fatty acid synthase is up-regulated during hepatitis C virus infection and regulates hepatitis C virus entry and production.
Hepatology (Baltimore, Md.)
Yang W,Hood BL,Chadwick SL,Liu S,Watkins SC,Luo G,Conrads TP,Wang T
33-9100 was used in immunocytochemistry to investigate the function of fatty acid synthase in cells infected with hepatitis C virus
Sat Nov 01 00:00:00 EDT 2008
Connexin45-containing neuronal gap junctions in rodent retina also contain connexin36 in both apposing hemiplaques, forming bihomotypic gap junctions, with scaffolding contributed by zonula occludens-1.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Li X,Kamasawa N,Ciolofan C,Olson CO,Lu S,Davidson KG,Yasumura T,Shigemoto R,Rash JE,Nagy JI
33-9100 was used in Immunocytochemistry to demonstrate that in Cx45-expressing neurons of IPL, Cx45 is almost always accompanied by Cx36, forming bihomotypic gap junctions.
Wed Sep 24 00:00:00 EDT 2008
N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility.
Journal of molecular and cellular cardiology
Li J,Levin MD,Xiong Y,Petrenko N,Patel VV,Radice GL
33-9100 was used in immunocytochemistry to explore the relationship between N-cadherin and connexin43 in the heart
Sat Mar 01 00:00:00 EST 2008
Occludin oligomeric assembly at tight junctions of the blood-brain barrier is disrupted by peripheral inflammatory hyperalgesia.
Journal of neurochemistry
McCaffrey G,Seelbach MJ,Staatz WD,Nametz N,Quigley C,Campos CR,Brooks TA,Davis TP
33-9100 was used in immunohistochemistry and western blot to test the effect of lambda-carrageenan-induced peripheral inflammatory pain on occludin.
Mon Sep 01 00:00:00 EDT 2008
aPKC enables development of zonula adherens by antagonizing centripetal contraction of the circumferential actomyosin cables.
Journal of cell science
Kishikawa M,Suzuki A,Ohno S
33-9100 was used in immunocytochemistry to investigate the role of aPKC kinase activity on actomyosin contraction
Fri Aug 01 00:00:00 EDT 2008
Early events in HIV transmission through a human reconstructed vaginal mucosa.
AIDS (London, England)
Bouschbacher M,Bomsel M,Verronèse E,Gofflo S,Ganor Y,Dezutter-Dambuyant C,Valladeau J
33-9100 was used in immunohistochemistry - paraffin section to study translocation of HIV across the vaginal pluristratified epithelium
Fri Jul 11 00:00:00 EDT 2008
Interleukin 1 alpha (IL1A) is a novel regulator of the blood-testis barrier in the rat.
Biology of reproduction
Sarkar O,Mathur PP,Cheng CY,Mruk DD
33-9100 was used in Western Blotting to study the role of interleukin 1 alpha in the regulation of the blood-testis barrier in rats.
Sat Mar 01 00:00:00 EST 2008
Phosphorylation of claudin-4 is required for tight junction formation in a human keratinocyte cell line.
Experimental cell research
Aono S,Hirai Y
33-9100 was used in immunocytochemistry and western blot to suggest that aPKC regulates tight junction formation through the phosphorylation of claudin-4
Sat Nov 01 00:00:00 EDT 2008
Expression and localisation of apical junctional complex proteins in lens epithelial cells.
Experimental eye research
Sugiyama Y,Prescott AR,Tholozan FM,Ohno S,Quinlan RA
33-9100 was used in immunohistochemistry and western blot to determine the composition of the apical junctional complex present in lens epithelial cells
Tue Jul 01 00:00:00 EDT 2008
Localization of semaphorin 3A in the rat cornea.
Experimental eye research
Morishige N,Ko JA,Liu Y,Chikama T,Nishida T
33-9100 was used in immunohistochemistry to study the localization of Sema3A in the cornea
Tue Apr 01 00:00:00 EDT 2008
Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation.
Neuroscience
Roberts LM,Black DS,Raman C,Woodford K,Zhou M,Haggerty JE,Yan AT,Cwirla SE,Grindstaff KK
33-9100 was used in immunohistochemistry to study the luminal/abluminal localization of a number of blood-brain barrier transporters expressed by endothelial cells
Wed Aug 13 00:00:00 EDT 2008
Expression of Claudin-1, Claudin-3 and Claudin-5 in human blood-brain barrier mimicking cell line ECV304 is inducible by glioma-conditioned media.
Neuroscience letters
Neuhaus W,Wirth M,Plattner VE,Germann B,Gabor F,Noe CR
33-9100 was used in immunocytochemistry to study tight junction proteins in ECV304 cells
Wed Dec 03 00:00:00 EST 2008
Effects of multipurpose solutions on corneal epithelial tight junctions.
Eye & contact lens
Imayasu M,Shiraishi A,Ohashi Y,Shimada S,Cavanagh HD
33-9100 was used in immunocytochemistry to compare the effects of four commercially available multipurpose solutions on the structure and barrier function of corneal epithelial tight junctions
Tue Jan 01 00:00:00 EST 2008
Differential requirement for beta-catenin in epithelial and fiber cells during lens development.
Developmental biology
Cain S,Martinez G,Kokkinos MI,Turner K,Richardson RJ,Abud HE,Huelsken J,Robinson ML,de Iongh RU
33-9100 was used in immunohistochemistry - paraffin section to determine the effect of beta-catenin loss during lens development
Mon Sep 15 00:00:00 EDT 2008
Protein components of the blood-brain barrier (BBB) in the mediobasal hypothalamus.
Journal of chemical neuroanatomy
Norsted E,Gömüç B,Meister B
33-9100 was used in immunohistochemistry - frozen section to characterize the blood brain barrier in the median eminence-arcuate nucleus complex
Wed Oct 01 00:00:00 EDT 2008
Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos.
Mechanisms of development
Nishioka N,Yamamoto S,Kiyonari H,Sato H,Sawada A,Ota M,Nakao K,Sasaki H
33-9100 was used in immunohistochemistry to report that Tead4 is required for trophectoderm development
Tue Apr 08 00:00:00 EDT 2008
Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions.
Genome biology
Birnie R,Bryce SD,Roome C,Dussupt V,Droop A,Lang SH,Berry PA,Hyde CF,Lewis JL,Stower MJ,Maitland NJ,Collins AT
33-9100 was used in flow cytometry to describe a cancer stem cell gene-expression signature
Mon Jul 21 00:00:00 EDT 2008
Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression.
Molecular membrane biology
Paschoud S,Citi S
33-9100 was used in immunocytochemistry and western blot to study the effects of cingulin overexpression
Tue Jan 01 00:00:00 EST 2008
C-terminal truncation of connexin43 changes number, size, and localization of cardiac gap junction plaques.
Circulation research
Maass K,Shibayama J,Chase SE,Willecke K,Delmar M
33-9100 was used in Immunoprecipitation to conclude that the carboxyl-terminal domain of Cx43 (Cx43CT) is involved in regulating the localization, number and size of Cx43 plaques in vivo.
Fri Dec 07 00:00:00 EST 2007
C-terminal truncation of connexin43 changes number, size, and localization of cardiac gap junction plaques.
Circulation research
Maass K,Shibayama J,Chase SE,Willecke K,Delmar M
33-9100 was used in Immunoprecipitation to conclude that the carboxyl-terminal domain of Cx43 (Cx43CT) is involved in regulating the localization, number and size of Cx43 plaques in vivo.
Fri Dec 07 00:00:00 EST 2007
Novel fibroblastic onion bulbs in a demyelinating avian peripheral neuropathy produced by riboflavin deficiency.
Acta neuropathologica
Cai Z,Blumbergs PC,Finnie JW,Manavis J,Thompson PD
33-9100 was used in immunohistochemistry - paraffin section to study the fibroblastic onion bulb-like structures in peripheral nerves of chickens
Wed Aug 01 00:00:00 EDT 2007
Basal cells of the human adult airway surface epithelium retain transit-amplifying cell properties.
Stem cells (Dayton, Ohio)
Hajj R,Baranek T,Le Naour R,Lesimple P,Puchelle E,Coraux C
33-9100 was used in immunohistochemistry to evaluate the capacity of human adult basal cells to restore a well-differentiated and functional airway epithelium
Mon Jan 01 00:00:00 EST 2007
Tmod3 regulates polarized epithelial cell morphology.
Journal of cell science
Weber KL,Fischer RS,Fowler VM
33-9100 was used in immunocytochemistry to analyze regulation of polarized epithelial cell morphology by Tmod3
Mon Oct 15 00:00:00 EDT 2007
Expression of JAM-A in the human corneal endothelium and retinal pigment epithelium: localization and evidence for role in barrier function.
Investigative ophthalmology & visual science
Mandell KJ,Berglin L,Severson EA,Edelhauser HF,Parkos CA
33-9100 was used in immunocytochemistry to quantify junctional adhesion molecule-A expression in human corneal endothelium and retinal pigment epithelium and examine the impact of a junctional adhesion molecule-A function-blocking antibody on the permeab
Sat Sep 01 00:00:00 EDT 2007
Interleukin-13 interferes with CFTR and AQP5 expression and localization during human airway epithelial cell differentiation.
Experimental cell research
Skowron-zwarg M,Boland S,Caruso N,Coraux C,Marano F,Tournier F
33-9100 was used in immunocytochemistry to investigate the role of the interleukin-13 in human airway epithelial cell differentiation
Sun Jul 15 00:00:00 EDT 2007
Evidence for HSP-mediated cytoskeletal stabilization in mesothelial cells during acute experimental peritoneal dialysis.
American journal of physiology. Renal physiology
Endemann M,Bergmeister H,Bidmon B,Boehm M,Csaicsich D,Malaga-Dieguez L,Arbeiter K,Regele H,Herkner K,Aufricht C
33-9100 was used in immunocytochemistry and western blot to explore the role of heat shock proteins in cytoskeletal stabilization of mesothelial cells in experimental peritoneal dialysis
Mon Jan 01 00:00:00 EST 2007
Spatial relationships of connexin36, connexin57 and zonula occludens-1 in the outer plexiform layer of mouse retina.
Neuroscience
Ciolofan C,Lynn BD,Wellershaus K,Willecke K,Nagy JI
33-9100 was used in immunohistochemistry to investigate connexin57 expression in the mouse retina
Fri Aug 24 00:00:00 EDT 2007
Serosal mesothelium retains vasculogenic potential.
Developmental dynamics : an official publication of the American Association of Anatomists
Kawaguchi M,Bader DM,Wilm B
33-9100 was used in immunocytochemistry to develop an in vitro system to analyze the differentiative potential of mesothelia
Thu Nov 01 00:00:00 EDT 2007
Immunolocalization of tight junction proteins in blood vessels in human germinal matrix and cortex.
Histochemistry and cell biology
Anstrom JA,Thore CR,Moody DM,Brown WR
33-9100 was used in immunohistochemistry to test if the expression of tight junction proteins increases in vessels of germinal matrix and cortex with gestational age
Thu Feb 01 00:00:00 EST 2007
Rab4A GTPase catenin interactions are involved in cell junction dynamics in the testis.
Journal of andrology
Mruk DD,Lau AS,Sarkar O,Xia W
33-9100 was used in Western Blotting to suggest that Rab4A participates in adherens junction dynamics in the testis.
Thu Dec 27 00:00:00 EST 2007
PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains.
Development (Cambridge, England)
Hirose T,Karasawa M,Sugitani Y,Fujisawa M,Akimoto K,Ohno S,Noda T
33-9100 was used in immunohistochemistry - frozen section to report that disruption of the mouse Par3 gene results in midgestational embryonic lethality with defective epicardial development
Sat Apr 01 00:00:00 EST 2006
Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.
Development (Cambridge, England)
Imai F,Hirai S,Akimoto K,Koyama H,Miyata T,Ogawa M,Noguchi S,Sasaoka T,Noda T,Ohno S
33-9100 was used in immunohistochemistry - paraffin section to examine the role of atypical protein kinase C lambda in mouse neocortical neurogenesis
Mon May 01 00:00:00 EDT 2006
Adjudin-mediated junction restructuring in the seminiferous epithelium leads to displacement of soluble guanylate cyclase from adherens junctions.
Journal of cellular physiology
Sarkar O,Xia W,Mruk DD
33-9100 was used in immunoprecipitation and western blot to determine the role of soluble guanylate cyclase in junction restructuring of the seminiferous epithelium of rat testis
Sat Jul 01 00:00:00 EDT 2006
Antibody blockade of junctional adhesion molecule-A in rabbit corneal endothelial tight junctions produces corneal swelling.
Investigative ophthalmology & visual science
Mandell KJ,Holley GP,Parkos CA,Edelhauser HF
33-9100 was used in western blot to determine JAM-A expression and function in the corneal endothelium
Thu Jun 01 00:00:00 EDT 2006
Tumor necrosis factor {alpha} reversibly disrupts the blood-testis barrier and impairs Sertoli-germ cell adhesion in the seminiferous epithelium of adult rat testes.
The Journal of endocrinology
Li MW,Xia W,Mruk DD,Wang CQ,Yan HH,Siu MK,Lui WY,Lee WM,Cheng CY
33-9100 was used in Immunocytochemistry-immunoflourescence to illustrate that the blood-testis barrier is likely utilizing a novel mechanism where TNFalpha production facilitates germ cell migration during spermatogenesis.
Tue Aug 01 00:00:00 EDT 2006
Tight junction proteins and perineurial cells in neurofibromas.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Pummi KP,Aho HJ,Laato MK,Peltonen JT,Peltonen SA
33-9100 was used in immunohistochemistry - frozen section to determine the distribution and role of perineurial cells in neurofibromas
Sun Jan 01 00:00:00 EST 2006
Altered expression of junctional adhesion molecule 4 in injured podocytes.
American journal of physiology. Renal physiology
Harita Y,Miyauchi N,Karasawa T,Suzuki K,Han GD,Koike H,Igarashi T,Shimizu F,Kawachi H
Wed Feb 01 00:00:00 EST 2006
A dileucine motif targets MCAM-l cell adhesion molecule to the basolateral membrane in MDCK cells.
FEBS letters
Guezguez B,Vigneron P,Alais S,Jaffredo T,Gavard J,Mège RM,Dunon D
33-9100 was used in immunocytochemistry to analyze a target of MCAM-I cell adhesion molecule to the basolateral membrane in MDCK cells by a dileucine motif
Mon Jun 26 00:00:00 EDT 2006
Laminin alpha 3 forms a complex with beta3 and gamma3 chains that serves as the ligand for alpha 6beta1-integrin at the apical ectoplasmic specialization in adult rat testes.
The Journal of biological chemistry
Yan HHN,Cheng CY
33-9100 was used in Immunohistochemistry-immunofluorescence to characterise the laminin chains expressed in cells of the seminiferous epithelium in the rat testes.
Fri Jun 23 00:00:00 EDT 2006
Down-regulation of CD9 in human ovarian carcinoma cell might contribute to peritoneal dissemination: morphologic alteration and reduced expression of beta1 integrin subsets.
Cancer research
Furuya M,Kato H,Nishimura N,Ishiwata I,Ikeda H,Ito R,Yoshiki T,Ishikura H
Fri Apr 01 00:00:00 EST 2005
Membrane-type 1 matrix metalloproteinase expression is regulated by zonula occludens-1 in human breast cancer cells.
Cancer research
Polette M,Gilles C,Nawrocki-Raby B,Lohi J,Hunziker W,Foidart JM,Birembaut P
Thu Sep 01 00:00:00 EDT 2005
Membrane-type 1 matrix metalloproteinase expression is regulated by zonula occludens-1 in human breast cancer cells.
Cancer research
Polette M,Gilles C,Nawrocki-Raby B,Lohi J,Hunziker W,Foidart JM,Birembaut P
Thu Sep 01 00:00:00 EDT 2005
Albumin endocytosis in proximal tubule cells is modulated by angiotensin II through an AT2 receptor-mediated protein kinase B activation.
Proceedings of the National Academy of Sciences of the United States of America
Caruso-Neves C,Kwon SH,Guggino WB
Tue Nov 29 00:00:00 EST 2005
Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells.
Laboratory investigation; a journal of technical methods and pathology
Prasad S,Mingrino R,Kaukinen K,Hayes KL,Powell RM,MacDonald TT,Collins JE
Thu Sep 01 00:00:00 EDT 2005
Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations.
American journal of physiology. Heart and circulatory physiology
Brooks TA,Hawkins BT,Huber JD,Egleton RD,Davis TP
Mon Aug 01 00:00:00 EDT 2005
Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations.
American journal of physiology. Heart and circulatory physiology
Brooks TA,Hawkins BT,Huber JD,Egleton RD,Davis TP
Mon Aug 01 00:00:00 EDT 2005
Blood-testis barrier dynamics are regulated by {alpha}2-macroglobulin via the c-Jun N-terminal protein kinase pathway.
Endocrinology
Wong CH,Mruk DD,Siu MK,Cheng CY
33-9100 was used in Immunohistochemistry-immunofluorescence to elucidate the regulation of blood-testis barrier dynamics by alpha(2)-macroglobulin.
Fri Apr 01 00:00:00 EST 2005
sPAR-3, a splicing variant of PAR-3, shows cellular localization and an expression pattern different from that of PAR-3 during enterocyte polarization.
American journal of physiology. Gastrointestinal and liver physiology
Yoshii T,Mizuno K,Hirose T,Nakajima A,Sekihara H,Ohno S
Tue Mar 01 00:00:00 EST 2005
sPAR-3, a splicing variant of PAR-3, shows cellular localization and an expression pattern different from that of PAR-3 during enterocyte polarization.
American journal of physiology. Gastrointestinal and liver physiology
Yoshii T,Mizuno K,Hirose T,Nakajima A,Sekihara H,Ohno S
Tue Mar 01 00:00:00 EST 2005
Expression of zonula occludens-1 (ZO-1) and the transcription factor ZO-1-associated nucleic acid-binding protein (ZONAB)-MsY3 in glial cells and colocalization at oligodendrocyte and astrocyte gap junctions in mouse brain.
The European journal of neuroscience
Penes MC,Li X,Nagy JI
Fri Jul 01 00:00:00 EDT 2005
Functional organization of the bovine rumen epithelium.
American journal of physiology. Regulatory, integrative and comparative physiology
Graham C,Simmons NL
Sat Jan 01 00:00:00 EST 2005
Functional organization of the bovine rumen epithelium.
American journal of physiology. Regulatory, integrative and comparative physiology
Graham C,Simmons NL
Sat Jan 01 00:00:00 EST 2005
Vezatin, a protein associated to adherens junctions, is required for mouse blastocyst morphogenesis.
Developmental biology
Hyenne V,Louvet-Vallée S,El-Amraoui A,Petit C,Maro B,Simmler MC
33-9100 was used in immunocytochemistry to study the requirement for mouse blastocyst morphogenesis by a protein associated to adherens junctions called vezatin
Tue Nov 01 00:00:00 EST 2005
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells.
The Journal of biological chemistry
Wei CJ,Francis R,Xu X,Lo CW
Fri May 20 00:00:00 EDT 2005
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells.
The Journal of biological chemistry
Wei CJ,Francis R,Xu X,Lo CW
Fri May 20 00:00:00 EDT 2005
Localization of PDZ domain containing proteins Discs Large-1 and Scribble in the mouse eye.
Molecular vision
Nguyen MM,Rivera C,Griep AE
33-9100 was used in immunohistochemistry - paraffin section to determine the distribution of Dlg-1 and Scrib in various structures of the mouse eye
Wed Dec 28 00:00:00 EST 2005
The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.
The Journal of biological chemistry
Lopez C,Métral S,Eladari D,Drevensek S,Gane P,Chambrey R,Bennett V,Cartron JP,Le Van Kim C,Colin Y
Fri Mar 04 00:00:00 EST 2005
Extracellular signal-regulated kinases 1/2 control claudin-2 expression in Madin-Darby canine kidney strain I and II cells.
The Journal of biological chemistry
Lipschutz JH,Li S,Arisco A,Balkovetz DF
Fri Feb 04 00:00:00 EST 2005
Extracellular signal-regulated kinases 1/2 control claudin-2 expression in Madin-Darby canine kidney strain I and II cells.
The Journal of biological chemistry
Lipschutz JH,Li S,Arisco A,Balkovetz DF
Fri Feb 04 00:00:00 EST 2005
The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation.
Nature
Parker LH,Schmidt M,Jin SW,Gray AM,Beis D,Pham T,Frantz G,Palmieri S,Hillan K,Stainier DY,De Sauvage FJ,Ye W
Thu Apr 15 00:00:00 EDT 2004
The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation.
Nature
Parker LH,Schmidt M,Jin SW,Gray AM,Beis D,Pham T,Frantz G,Palmieri S,Hillan K,Stainier DY,De Sauvage FJ,Ye W
Thu Apr 15 00:00:00 EDT 2004
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis.
Nature
Koga T,Inui M,Inoue K,Kim S,Suematsu A,Kobayashi E,Iwata T,Ohnishi H,Matozaki T,Kodama T,Taniguchi T,Takayanagi H,Takai T
33-9100 was used in Immunofluorescence in immunohistochemistry on frozen tissues to clarify how RANKL activates the calcium signals that lead to induction of nuclear factor of activated T cells c1, a key transcription factor for osteoclastogenesis.
Thu Apr 15 00:00:00 EDT 2004
Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization.
The EMBO journal
Moeller MJ,Soofi A,Braun GS,Li X,Watzl C,Kriz W,Holzman LB
33-9100 was used in immunocytochemistry to study cell polarization and actin dynamics by protocadherin FAT1 binding Ena/VASP proteins
Fri Oct 01 00:00:00 EDT 2004
Abnormal expression of molecular markers for bladder impermeability and differentiation in the urothelium of patients with interstitial cystitis.
The Journal of urology
Slobodov G,Feloney M,Gran C,Kyker KD,Hurst RE,Culkin DJ
33-9100 was used in immunohistochemistry to study E-cadherin, ZO-1, uroplakin, and chondroitin sulfate in interstitial cystitis samples
Thu Apr 01 00:00:00 EST 2004
Estrogen abrogates transcervical tight junctional resistance by acceleration of occludin modulation.
The Journal of clinical endocrinology and metabolism
Zeng R,Li X,Gorodeski GI
33-9100 was used in immunocytochemistry to investigate the effects of estrogen on transcervical tight-junctional resistance
Fri Oct 01 00:00:00 EDT 2004
An in vitro model based on cell monolayers grown on the underside of large- pore filters in bicameral chambers for studying thyrocyte-lymphocyte interactions.
American journal of physiology. Cell physiology
Estienne V,Brisbarre N,Blanchin S,Durand-Gorde JM,Carayon P,Ruf J
Wed Dec 01 00:00:00 EST 2004
Trafficking of cholera toxin-ganglioside GM1 complex into Golgi and induction of toxicity depend on actin cytoskeleton.
American journal of physiology. Cell physiology
Badizadegan K,Wheeler HE,Fujinaga Y,Lencer WI
Mon Nov 01 00:00:00 EST 2004
Ochratoxin A increases permeability through tight junctions by removal of specific claudin isoforms.
American journal of physiology. Cell physiology
McLaughlin J,Padfield PJ,Burt JP,O'Neill CA
Mon Nov 01 00:00:00 EST 2004
Ochratoxin A increases permeability through tight junctions by removal of specific claudin isoforms.
American journal of physiology. Cell physiology
McLaughlin J,Padfield PJ,Burt JP,O'Neill CA
Mon Nov 01 00:00:00 EST 2004
Regulation of blood-testis barrier dynamics: an in vivo study.
Journal of cell science
Wong CH,Mruk DD,Lui WY,Cheng CY
33-9100 was used in Immunofluorescence to investigate the regulation of tight junction dynamics in the testis when adult rats are treated with cadmium chloride.
Sun Feb 15 00:00:00 EST 2004
Bves is expressed in the epithelial components of the retina, lens, and cornea.
Investigative ophthalmology & visual science
Ripley AN,Chang MS,Bader DM
33-9100 was used in Immunohistochemistry-immunofluorescence to demonstrate the expression pattern and subcellular localisation of Bves/Pop1a protein.
Sun Aug 01 00:00:00 EDT 2004
Tight junction proteins ZO-1, occludin, and claudins in developing and adult human perineurium.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Pummi KP,Heape AM,Grénman RA,Peltonen JT,Peltonen SA
33-9100 was used in immunohistochemistry to report the expression of tight junction proteins in the perineurium of adult human peripheral nerve
Sun Aug 01 00:00:00 EDT 2004
Expression of claudin-7 and -8 along the mouse nephron.
American journal of physiology. Renal physiology
Li WY,Huey CL,Yu AS
Tue Jun 01 00:00:00 EDT 2004
Neuronal connexin36 association with zonula occludens-1 protein (ZO-1) in mouse brain and interaction with the first PDZ domain of ZO-1.
The European journal of neuroscience
Li X,Olson C,Lu S,Kamasawa N,Yasumura T,Rash JE,Nagy JI
Thu Apr 01 00:00:00 EST 2004
Expression of a novel secretory form (Crb1s) of mouse Crumbs homologue Crb1 in skin development.
Biochemical and biophysical research communications
Watanabe T,Miyatani S,Katoh I,Kobayashi S,Ikawa Y
33-9100 was used in immunocytochemistry to study the expression and localization of Crb1s
Fri Jan 09 00:00:00 EST 2004
Association of connexin36 with zonula occludens-1 in HeLa cells, betaTC-3 cells, pancreas, and adrenal gland.
Histochemistry and cell biology
Li X,Olson C,Lu S,Nagy JI
33-9100 was used in immunocytochemistry, immunohistochemistry - frozen section, and immunoprecipitation to assess the association of connexin36 with ZO-1 in various cultured cells and tissues
Mon Nov 01 00:00:00 EST 2004
The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction.
The Journal of biological chemistry
Coyne CB,Voelker T,Pichla SL,Bergelson JM
Fri Nov 12 00:00:00 EST 2004
The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction.
The Journal of biological chemistry
Coyne CB,Voelker T,Pichla SL,Bergelson JM
Fri Nov 12 00:00:00 EST 2004
The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction.
The Journal of biological chemistry
Coyne CB,Voelker T,Pichla SL,Bergelson JM
Fri Nov 12 00:00:00 EST 2004
The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction.
The Journal of biological chemistry
Coyne CB,Voelker T,Pichla SL,Bergelson JM
Fri Nov 12 00:00:00 EST 2004
The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction.
The Journal of biological chemistry
Coyne CB,Voelker T,Pichla SL,Bergelson JM
Fri Nov 12 00:00:00 EST 2004
The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction.
The Journal of biological chemistry
Coyne CB,Voelker T,Pichla SL,Bergelson JM
Fri Nov 12 00:00:00 EST 2004
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.
Cancer cell
Lu Z,Ghosh S,Wang Z,Hunter T
Mon Dec 01 00:00:00 EST 2003
Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.
Cancer research
Anders M,Christian C,McMahon M,McCormick F,Korn WM
Thu May 01 00:00:00 EDT 2003
Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.
Cancer research
Anders M,Christian C,McMahon M,McCormick F,Korn WM
Thu May 01 00:00:00 EDT 2003
Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.
Cancer research
Anders M,Christian C,McMahon M,McCormick F,Korn WM
Thu May 01 00:00:00 EDT 2003
Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.
Cancer research
Anders M,Christian C,McMahon M,McCormick F,Korn WM
Thu May 01 00:00:00 EDT 2003
Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.
Cancer research
Anders M,Christian C,McMahon M,McCormick F,Korn WM
Thu May 01 00:00:00 EDT 2003
Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.
Cancer research
Anders M,Christian C,McMahon M,McCormick F,Korn WM
Thu May 01 00:00:00 EDT 2003
Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.
Cancer research
Anders M,Christian C,McMahon M,McCormick F,Korn WM
Thu May 01 00:00:00 EDT 2003
Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.
Cancer research
Anders M,Christian C,McMahon M,McCormick F,Korn WM
Thu May 01 00:00:00 EDT 2003
Immunohistological distribution of the tight junction components ZO-1 and occludin in regenerating human epidermis.
The British journal of dermatology
Malminen M,Koivukangas V,Peltonen J,Karvonen SL,Oikarinen A,Peltonen S
33-9100 was used in immunohistochemistry to discuss methods to study tight junctions.
Fri Aug 01 00:00:00 EDT 2003
Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast.
Oncogene
Kominsky SL,Argani P,Korz D,Evron E,Raman V,Garrett E,Rein A,Sauter G,Kallioniemi OP,Sukumar S
Thu Apr 03 00:00:00 EST 2003
Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast.
Oncogene
Kominsky SL,Argani P,Korz D,Evron E,Raman V,Garrett E,Rein A,Sauter G,Kallioniemi OP,Sukumar S
Thu Apr 03 00:00:00 EST 2003
Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture.
American journal of physiology. Cell physiology
Colegio OR,Van Itallie C,Rahner C,Anderson JM
Sun Jun 01 00:00:00 EDT 2003
Effects of hypoxia-reoxygenation on rat blood-brain barrier permeability and tight junctional protein expression.
American journal of physiology. Heart and circulatory physiology
Witt KA,Mark KS,Hom S,Davis TP
Mon Dec 01 00:00:00 EST 2003
Rab8B GTPase and junction dynamics in the testis.
Endocrinology
Lau AS,Mruk DD
33-9100 was used in western blot to elucidate the role of Rab8B in germ cell movement.
Tue Apr 01 00:00:00 EST 2003
Isolation and characterization of human esophageal microvascular endothelial cells: mechanisms of inflammatory activation.
American journal of physiology. Gastrointestinal and liver physiology
Rafiee P,Ogawa H,Heidemann J,Li MS,Aslam M,Lamirand TH,Fisher PJ,Graewin SJ,Dwinell MB,Johnson CP,Shaker R,Binion DG
Mon Dec 01 00:00:00 EST 2003
Claudin-8 expression in Madin-Darby canine kidney cells augments the paracellular barrier to cation permeation.
The Journal of biological chemistry
Yu AS,Enck AH,Lencer WI,Schneeberger EE
Fri May 09 00:00:00 EDT 2003
Claudin-8 expression in Madin-Darby canine kidney cells augments the paracellular barrier to cation permeation.
The Journal of biological chemistry
Yu AS,Enck AH,Lencer WI,Schneeberger EE
Fri May 09 00:00:00 EDT 2003
CLIC4 is enriched at cell-cell junctions and colocalizes with AKAP350 at the centrosome and midbody of cultured mammalian cells.
Cell motility and the cytoskeleton
Berryman MA,Goldenring JR
33-9100 was used in immunocytochemistry to investigate the localization and function of CLIC4
Sat Nov 01 00:00:00 EST 2003
Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells.
Developmental dynamics : an official publication of the American Association of Anatomists
Manabe N,Hirai S,Imai F,Nakanishi H,Takai Y,Ohno S
33-9100 was used in immunohistochemistry (paraffin) to determine the localization of atypical PKC isotype-specific interacting protein (ASIP) in embryonic neural tissues.
Sun Sep 01 00:00:00 EDT 2002
JEAP, a novel component of tight junctions in exocrine cells.
The Journal of biological chemistry
Nishimura M,Kakizaki M,Ono Y,Morimoto K,Takeuchi M,Inoue Y,Imai T,Takai Y
Fri Feb 15 00:00:00 EST 2002
Casein kinase 1 regulates connexin-43 gap junction assembly.
The Journal of biological chemistry
Cooper CD,Lampe PD
33-9100 was used in Western Blot to examine the role of casein kinase 1 in connexin-43 gap junction assembly.
Fri Nov 22 00:00:00 EST 2002
Casein kinase 1 regulates connexin-43 gap junction assembly.
The Journal of biological chemistry
Cooper CD,Lampe PD
33-9100 was used in Western Blot to examine the role of casein kinase 1 in connexin-43 gap junction assembly.
Fri Nov 22 00:00:00 EST 2002
The carboxyl terminus of zona occludens-3 binds and recruits a mammalian homologue of discs lost to tight junctions.
The Journal of biological chemistry
Roh MH,Liu CJ,Laurinec S,Margolis B
Fri Jul 26 00:00:00 EDT 2002
Applications of epithelial cell culture in studies of drug transport.
Methods in molecular biology (Clifton, N.J.)
Tavelin S,Gråsjö J,Taipalensuu J,Ocklind G,Artursson P
33-9100 was used in immunocytochemistry to review applications of epithelial cell culture in studies of drug transport
Tue Nov 12 00:00:00 EST 2002
Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability.
The Journal of clinical investigation
Van Itallie C,Rahner C,Anderson JM
Tue May 01 00:00:00 EDT 2001
Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability.
The Journal of clinical investigation
Van Itallie C,Rahner C,Anderson JM
Tue May 01 00:00:00 EDT 2001
Epidermal tight junctions: ZO-1 and occludin are expressed in mature, developing, and affected skin and in vitro differentiating keratinocytes.
The Journal of investigative dermatology
Pummi K,Malminen M,Aho H,Karvonen SL,Peltonen J,Peltonen S
33-9100 was used in immunohistochemistry - paraffin section and western blot to test if tight junction antigens are present in adult and developing human epidermis.
Thu Nov 01 00:00:00 EST 2001
